Endomysial Antibody, IgG

Endomysial Antibody, IgG test helps in the detection of IgG-endomysial antibodies for the diagnosis of dermatitis herpetiformis and celiac disease, and for monitoring adherence to a gluten-free diet. In celiac disease, the immune system mistakenly identifies gluten, a protein found in wheat, barley, and rye, as a foreign invader and produces IgG-EMA antibodies that attack the endomysium in the small intestine. This can lead to inflammation and damage to the intestinal lining, which can cause a range of symptoms including diarrhea, abdominal pain, skin rash, joint pain, and malabsorption of nutrients causing weight loss and fatigue. The detection of IgG-EMA in serum is commonly used as a diagnostic tool for celiac disease, In patients with low levels of IgA and children less than 3 years of age.