ASCA - IgA antibody

Saccharomyces cerevisiae is a harmless yeast found in food, the body, and the environment. In certain individuals, the immune system reacts to this yeast and produces antibodies against it. These antibodies, called anti-Saccharomyces cerevisiae antibodies (ASCA), are commonly linked with Crohn’s disease. Specifically, the ASCA-IgA test looks for IgA antibodies, which are closely associated with mucosal immunity in the intestines.

Detecting ASCA-IgA helps doctors differentiate Crohn’s disease from ulcerative colitis, two major forms of IBD that affect different regions of the gastrointestinal tract and often need different treatment approaches. The test is recommended for patients with gastrointestinal symptoms such as long-standing diarrhea, abdominal pain, unexplained weight loss, or rectal bleeding, especially if the diagnosis is unclear.

No special preparation is needed for getting the ASCA - IgA antibody test done. However, be sure to inform the doctor about any medications or supplements being taken, as they may affect the test results. 

Lab test results may vary across different laboratories. Abnormal test results require expert interpretation. Therefore, never try to self-medicate based solely on these results. Always consult a doctor for a proper understanding of the test results.

Please note: This is an outsourced test. The sample for this test is collected by TATA 1MG and processed at a NABL accredited partnered lab.