Cadila Pharmaceuticals Ltd

Composition for Zypara 750mg Tablet

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Primarily used for

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Medicine Overview of Zypara Tablet


Uses of Zypara Tablet

ZYPARA 750 MG TABLET is used in the treatment of tuberculosis.

Side effects of Zypara Tablet


Jaundice, Hepatitis (viral infection of liver), Increased liver enzymes, Joint pain.


How to use Zypara Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. ZYPARA 750 MG TABLET is to be taken with food.

How Zypara Tablet works

ZYPARA 750 MG TABLET is an antibiotic. It works by slowing the growth of bacteria that causes tuberculosis.

In Depth Information on Zypara Tablet

Expert advice for Zypara Tablet

  • Avoid alcoholic beverages while taking this drug.
  • Do not have any immunizations/vaccinations while using this medication without the consent of your doctor.
  • Contact your doctor immediately if you experience symptoms such as persistent nausea,  vomiting, feeling of discomfort (malaise) or jaundice (abnormal liver function causing yellowing of skin and eyes) while taking pyrazinamide. It indicates that you are developing liver disease.
  • Constant monitoring of liver function (especially levels of enzymes aspartate transferase [AST] and alanine transferase [ALT]) and blood uric acid levels is advised while on treatment with pyrazinamide.
  • Do consult your doctor before taking pyrazinamide if you are pregnant or planning to become pregnant.
  • Do not use pyrazinamide, if you are breast-feeding.
  • Do not stop taking pyrazinamide without consulting your doctor.
  • If you forget to take a dose of pyrazinamide, take it as soon as you remember. Do not double the dose to make up for the missed dose.
  • Do consult your doctor if you are taking oral contraceptive medications (hormonal birth control pills) for birth control. Your doctor may ask you to use other means of birth control (eg. condom, diaphragm with spermicide) to prevent pregnancy while taking pyrazinamide.
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Zypara Tablet related warnings
Special precautions for Zypara Tablet
Interaction with alcohol is unknown. Please consult your doctor.
ZYPARA 750 MG TABLET may be unsafe to use during pregnancy.

Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
ZYPARA 750 MG TABLET is probably safe to use during lactatio
n. Limited human data suggests that the drug does not represent a significant risk to the baby.
It is not known whether ZYPARA 750 MG TABLET alters the abil
ity to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
ZYPARA 750 MG TABLET should be used with caution in patients with severe kidney disease. Dose adjustment of ZYPARA 750 MG TABLET may be needed. Please consult your doctor.

Kidney function tests are advised before you start taking this medicine.
ZYPARA 750 MG TABLET should be used with caution in patients with liver disease. Dose adjustment of ZYPARA 750 MG TABLET may be needed. Please consult your doctor.

Regular monitoring of liver function tests is advised before and after the start of the treatment.
Severely interacts with other drugs like
Louric 100mg Tablet, Piloric 300mg Tablet, Zylotis 100mg Tablet, Axanthine 300mg Tablet

Missed Dosageuses

If you miss a dose of Pyrazinamide, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Patient Concerns

Frequently asked questions about Zypara Tablet

Frequently asked questions about Pyrazinamide

Zypara is an antibiotic. It is used in combination with other antibiotics in the treatment of tuberculosis
Zypara is both a bacteriostatic and a bactericidal antibiotic. It stops the growth of bacteria (bacteriostatic) in certain cases and kills (bactericidal) the tuberculosis causing bacteria in other cases
Zypara kills or stops growth of bacteria that causes tuberculosis (Mycobacterium tuberculosis). The exact mechanism of action for Zypara is not known
Following oral intake of Zypara, it gets converted in the body to pyrazinoic acid (active chemical form of Zypara). Pyrazinoic acid blocks the excretion of urates (salt form of uric acid) by the kidneys. This causes an increase in blood levels of uric acid (hyperuricemia). Excess uric acid accumulation between joints causes pain, swelling, redness and stiffness in joints (gout).

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Top Physicians
Dr. Pooja Khosla
MBBS, MD, Fellowship
Dr. Sunil Sekhri
MBBS, Fellowship
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