Zynesp 40 Injection is used in the treatment of anemia that may have occurred due to chronic kidney disease or chemotherapy. It works by stimulating the bone marrow to produce more red blood cells.

Zynesp 40 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects. It is important that you seek treatment from a doctor who is experienced in providing this medical therapy. You should follow all the directions of the doctor strictly. It is given under the supervision of a healthcare professional.

It may cause side effects like high blood pressure and hypersensitivity. Inform your doctor if there are symptoms of very high blood pressure such as severe headache, problems with your eyesight, nausea, vomiting, or fits (seizures).

Your doctor may get your blood tests done regularly to monitor the levels of salts (electrolytes such as potassium), hemoglobin, and blood cells in your blood. You should stop taking it and consult with a doctor if you develop shortness of breath or skin rash.

Uses of Zynesp Injection

Benefits of Zynesp Injection

In Treatment of Anemia due to chronic kidney disease

Anemia is a condition where your body does not have enough red blood cells to carry oxygen around your body. Chronic kidney disease (CKD) refers to the loss of normal kidney function over a long span of time. CKD progresses gradually over a few years but may become permanent if left untreated. CKD can lead to anemia. Zynesp 40 Injection can boost your levels of red blood cells and reduce the symptoms of anemia such as tiredness and weakness. Taking this injection improves the quality of life.

In Treatment of Anemia due to cancer chemotherapy

Low red blood cell count is termed as anemia. Cancer treatment with chemotherapy often causes many side effects, one of the major ones being anemia. Zynesp 40 Injection stimulates the production of red blood cells in bone marrow and regulates the haemoglobin in the blood. This treats anemia in cancer patients receiving chemotherapy.

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Side effects of Zynesp Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zynesp

High blood pressure
Rash
Injection site pain
Breathlessness
Cough
Peripheral edema
Procedural hypotension (low blood pressure)
Convulsion
Thromboembolism

How to use Zynesp Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Zynesp Injection works

Zynesp 40 Injection is an erythropoiesis-stimulating agent (ESA). It works by stimulating the bone marrow (soft tissue inside the bones which produces red blood cells) to produce more red blood cells.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Zynesp 40 Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Zynesp 40 Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Zynesp 40 Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

SAFE

Zynesp 40 Injection does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Zynesp 40 Injection is safe to use in patients with kidney disease. No dose adjustment of Zynesp 40 Injection is recommended.

Liver

CAUTION

Zynesp 40 Injection should be used with caution in patients with liver disease. Dose adjustment of Zynesp 40 Injection may be needed. Please consult your doctor.

What if you forget to take Zynesp Injection?

If you miss a dose of Zynesp 40 Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

No substitutes found for this medicine

Quick tips

Zynesp 40 Injection helps in the treatment of anemia that may have occurred due to chronic kidney disease or cancer chemotherapy.
It is given as a single injection under your skin.
Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells and electrolytes such as potassium in your blood.
Stop taking Zynesp 40 Injection and inform your doctor if you develop shortness of breath or skin rash.

Fact Box

Chemical Class

Amino Acids, Peptides Analogues

Habit Forming

Therapeutic Class

BLOOD RELATED

Action Class

Erythropoiesis-stimulating agent (ESA)

Patient concerns

Blood Hb is found 5.9 so wat is it

Dr. Ila Jain Khandelwal

Pathology

Dear PATIENT from 1mg. The hemoglobin is very low, which can be due to anemia. I suggest you should consult a Hematologist /Physician for this.

how to resolve the problem of anemia?

Dr. Rekha Pohani

Dietetics/Nutrition

Intake of dates and jaggery will help

Weight loss is a challenge despite active lifestyle. Water retention. One kidney not functional. Anemia, hb 9.2.

Shikha Mishra

Dietetics/Nutrition

eat 6-7 meals per day, which consist fruits, nuts, buttermilk,sprouts,idly,curd eggs,sprouts homecooked food. Drink 3-4 litters of water limit your sugar consumption to 2 spoon per day. Be active whole day for personalized diet chart write to me on [email protected] do minimum 45 min exercise everyday like yoga, cardioare u taking treatment for kidney, if yes then consult dietician where u are going for treatment because it should be planned under doctor's guidance

User feedback

Patients taking Zynesp 40 Injection

Once A Week

57%

Twice A Month

22%

Once A Month

16%

Once A Day

Twice A Week

What are you using Zynesp Injection for?

Anemia due to*

100%

*Anemia due to chronic kidney disease

How much was the improvement?

Excellent

67%

Average

33%

What were the side-effects while using Zynesp 40 Injection?

Hypersensitiv*

50%

High blood pr*

50%

*Hypersensitivity, High blood pressure

How do you take Zynesp Injection?

With or witho*

100%

*With or without food

Please rate Zynesp 40 Injection on price

Not Expensive

100%

FAQs

Q. How long does it take for Zynesp 40 Injection to start working?

You will be able to notice an increase in the count of red blood cells (hemoglobin levels) in 2-6 weeks of starting Zynesp 40 Injection. If you have any other concerns, consult your doctor.

Q. Is Zynesp 40 Injection safe to use?

Zynesp 40 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects and even death of the patient. It is important that you seek treatment from a doctor who is experienced in providing Zynesp 40 Injection therapy. Follow all the directions strictly.

Q. Other than PRCA, can there be other reasons for not responding to Zynesp 40 Injection?

You may not respond to Zynesp 40 Injection if you have deficiencies of iron, folic acid or vitamin B12. It is important that you take measures to correct these deficiencies. Other reasons behind not responding to the treatment could be bleeding, infections, inflammation and bone marrow fibrosis. Therefore, consult our doctor regarding the same.

Q. Can Zynesp 40 Injection be used in children?

Yes, Zynesp 40 Injection is used to treat anemia due to chronic kidney disease in children who are above 1 year of age. The effectiveness of Zynesp 40 Injection and side effects seen in children are similar to adults. However, consult your doctor if you are not sure.

Q. Can Zynesp 40 Injection affect blood pressure?

Yes, Zynesp 40 Injection can affect blood pressure. During initial therapy with Zynesp 40 Injection, blood pressure should be monitored and those who have high blood pressure should take appropriate measures to control blood pressure. Your doctor may stop Zynesp 40 Injection if the blood pressure remains uncontrolled.

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Complete Blood Count

Peripheral Smear Examination

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Kaushansky K, Kipps TJ. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1071-72.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 358-59.
ScienceDirect. Darbepoetin alfa. [Accessed 07 Apr. 2019] (online) Available from:
Darbepoetin alfa. Milton Road, Cambridge: Amgen Ltd.; 2001 [revised Sep. 2017]. [Accessed 23 Jan. 2019] (online) Available from:
Darbepoetin alfa. Thousand Oaks, CA: Amgen Inc.; 2001. [Accessed 07 Apr. 2019] (online) Available from:

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.

Country of origin: India
Expires on or after: March, 2025

A licensed vendor partner from your nearest location will deliver Zynesp 40 Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India