Zuprinor 10 Transdermal Patch

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 28 Jan 2026 | 12:31 AM (IST)

Zuprinor 10 Transdermal Patch is used to treat moderate to severe pain and drug dependence/addiction to opioids. It helps prevent withdrawal symptoms that may be caused due to withdrawal of other opioids.

Genuine

Authenticity Assured

Prescription

required

₹1041 MRP ₹1153.1310% off

We do not facilitate sale of this product at present

Save more with additional offers

Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*

10% cashback up to 200 on Min Transaction of Rs.1000, for first time users of Airtel Payments Bank.

Get cashback up to ₹500

Get upto Rs.500 Cashback on minimum transaction of Rs.999/- with Mobikwik Wallet.

Save more with additional offers

Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*

10% cashback up to 200 on Min Transaction of Rs.1000, for first time users of Airtel Payments Bank.

Get cashback up to ₹500

Get upto Rs.500 Cashback on minimum transaction of Rs.999/- with Mobikwik Wallet.

Get upto Rs.150 Cashback

General Information

Contains

Buprenorphine (10mcg)

Marketer

Sun Pharmaceutical Industries Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Your doctor will explain how to use Zuprinor 10 Transdermal Patch. Follow the instructions carefully to get the most benefit. The dose and duration will depend on what you are using it for and how well it helps your symptoms. Use it regularly and do not discontinue using it until the doctor tells you it is alright to stop.

The most common side effects of this medicine include constipation, dizziness, drowsiness, headache, and nausea. You may have side effects more often when you start your treatment or when your dose is increased. Usually, the side effects will slowly go away as your body gets used to it. If they are severe or do not go away, you should remove your patch and contact your doctor.

Before using the medicine, you should tell your doctor if you have any other illnesses or disorders. It may also affect, or be affected by some other drugs you are using. Let your doctor know all the other medicines you are taking or using to make sure it is safe for you. Pregnant and breastfeeding women should consult their doctors first before using the medicine.

Uses of Zuprinor Transdermal Patch

Opioid (Morphine) dependence

Benefits of Zuprinor Transdermal Patch

Opioid (Morphine) dependence
Zuprinor 10 Transdermal Patch reduces cravings and withdrawal symptoms, making it easier for individuals to stop using opioids. As a partial opioid agonist, it helps stabilize brain function without producing the intense "high" associated with opioid misuse, which lowers the risk of relapse. Zuprinor 10 Transdermal Patch also supports long-term recovery by reducing the need for more harmful opioids and can be combined with counseling or behavioral therapies for a comprehensive approach to overcoming addiction.

Side effects of Zuprinor Transdermal Patch

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zuprinor

Headache
Drowsiness
Insomnia (difficulty in sleeping)
Dizziness
Vomiting
Weakness
Sweating
Nausea
Back pain
Abdominal pain
Constipation
Withdrawal syndrome
Infection
Vertigo
Inflammation of the nose
Chills
Flu-like symptoms

How to use Zuprinor Transdermal Patch

Use this medicine in dose and duration as advised by your doctor. Check the label before use. Make sure the skin is clean and dry. Remove the protective liner of the patch. Do not touch the sticky side. With sticky side down, place the patch evenly onto the skin.

How Zuprinor Transdermal Patch works

Zuprinor 10 Transdermal Patch is a opioid partial agonist. It prevents withdrawal symptoms in patients who stop taking opioid drugs by producing similar effects to these drugs. It also provides pain relief by acting on specific receptors in the brain that change how your body feels and responds to pain.

Quick tips

Zuprinor 10 Transdermal Patch should be used as advised by the doctor.
You should change the patch every 7 days and apply a new patch to a new site.
Do not expose the patches to a heat source.
Avoid drinking alcohol or taking other medicines that can cause drowsiness.
It has a high potential for abuse, misuse, or addiction even at normal doses.
Discontinue the medicine and inform your doctor if you experience difficulty breathing.
Do not stop taking Zuprinor 10 Transdermal Patch without talking to your doctor first as it may cause a worsening of symptoms.
Take it at the same time every day to help you remember to take it.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Use caution while driving or doing anything that requires concentration as Zuprinor 10 Transdermal Patch can cause dizziness and sleepiness.
Avoid drinking alcohol or taking other medicines that can cause drowsiness.
Discontinue the medicine and inform your doctor if you experience difficulty breathing.
Do not stop taking Zuprinor 10 Transdermal Patch without talking to your doctor first as it may cause a worsening of symptoms.
Your doctor may get regular blood tests to check for liver function while taking this medicine.

Safety advice

Alcohol

No interaction found/established

Pregnancy

CONSULT YOUR DOCTOR

Zuprinor 10 Transdermal Patch is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CAUTION

Zuprinor 10 Transdermal Patch should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

No interaction found/established

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Zuprinor 10 Transdermal Patch in patients with kidney disease. Please consult your doctor.

Liver

CAUTION

Zuprinor 10 Transdermal Patch should be used with caution in patients with liver disease. Dose adjustment may be needed.
Consider the use of an alternate analgesic that may permit more flexibility with the dosing in patients with severe hepatic impairment.

Interaction with drugs

Taking Zuprinor with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Naltrexone (Oral Route)

Do not consume Naltrexone with Buprenorphine; watch out for symptoms such as breathlessness, increased heart rate, or headache. Naltrexone may reduce efficacy of Buprenorphine.

Severe

Alprazolam (Oral Route)

If concurrent use is essential, watch out for symptoms of Alprazolam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Alprazolam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.

Severe

Alprazolam (Injection Route)

Severe

Chlordiazepoxide (Oral Route)

If concurrent use is essential, watch out for symptoms of Chlordiazepoxide side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Chlordiazepoxide as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.

Severe

Clobazam (Oral Route)

If concurrent use is essential, watch out for symptoms of Clobazam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Clobazam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.

Frequently asked questions

What is Zuprinor 10 Transdermal Patch used for?

Zuprinor 10 Transdermal Patch is used to relieve severe pain when other pain medicines did not work well enough or cannot be tolerated. This medicine is not used for minor pain or pain that only sometimes occurs. It should not be used to treat pain that you only have once in a while or "as needed". It is also used to treat opioid use disorder.

How to use Zuprinor 10 Transdermal Patch?

Zuprinor 10 Transdermal Patch should be applied to a clean, dry, rash-free, hairless, or nearly hairless area of skin on the upper chest, back, or arm, or side of the chest. Only use water to clean the area of skin prior to application because other substances (such as soaps, oils, or gels) may alter the absorption of the drug. Discard used patches carefully and out of reach of children or pets. Keep in mind that the skin is not the same everywhere on your body. Be sure to place the patch according to instructions from your doctor.

What precautions are to be taken while using Zuprinor 10 Transdermal Patch?

Do not use the skin patch if it has been cut or damaged. Never wear more than 1 patch at a time unless your doctor has told you to. Do not apply the patch to parts of the body that is irritated, broken, cut, or damaged. Do not wear the skin patch on a part of your body where your child could reach or remove the patch from your skin. Avoid allowing children to watch you put on a skin patch. Never tell a child that this skin patch is a "bandage."

What should I avoid while using Zuprinor 10 Transdermal Patch?

Avoid sources of heat while wearing the patch. Do not use a heating pad or electric blanket, tanning bed, or sauna. Avoid sunlight, hot bath water, and vigorous activity. Heat can increase the amount of the medicine you absorb through your skin and may cause an overdose or death.

Can I use one patch over another for better effect?

If you’re using more than one patch at a time, never place one patch on top of another. The entire sticky side needs to be in direct contact with your skin. It is advisable to always consult your doctor in case you have any doubts regarding the usage of this medicine.

I am not able to stick Zuprinor 10 Transdermal Patch onto my skin, can I use tape to stick?

If in case you are unable to stick the patch onto your skin do not use any dressing or tape. Talk to your doctor or pharmacist for advice.

Can I take bath or shower while using Zuprinor 10 Transdermal Patch?

Yes, you can have showers and even go swimming while using Zuprinor 10 Transdermal Patch but not for a long period of time. Check the patch is still on properly afterward and dry the area around the patch carefully. If your patch is missing, put another patch on a different part of your body and put the old patch back in the packet it came in. Use it as per your doctor's advice.

I feel dizzy when I get up from a sitting position or when I walk down the stairs. Is it due to Zuprinor 10 Transdermal Patch?

This medicine may cause a severe lowering of blood pressure, or a sudden drop in blood pressure when going from sitting to standing, especially if you are taking medications for high blood pressure. Talk to your doctor who might change your dosage.

When to consult the doctor?

Seek immediate medical help if you have shallow breathing, chest pain, fast heart rate, seizure, a light-headed feeling (like you might pass out), blisters, swelling, or severe irritation where the patch was worn, nausea, vomiting, loss of appetite or liver problems like upper stomach pain, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Can I use Zuprinor 10 Transdermal Patch during pregnancy?

If you use Zuprinor 10 Transdermal Patch while you are pregnant, your baby could become dependent on the medicine. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.

Can I use Zuprinor 10 Transdermal Patch while breastfeeding?

Zuprinor 10 Transdermal Patch can pass into breast milk and may cause breathing problems or at times or life-threatening problems in a breastfeeding baby. Ask your doctor in detail about all the risks.

How to safely store Zuprinor 10 Transdermal Patch?

As with most medications, Zuprinor 10 Transdermal Patch should be stored at room temperature. Store it in a secure location where it will not be exposed to excessive heat, moisture or direct sunlight. Keep it out of reach of children. Make sure that any leftover portion is disposed of safely.

Is Zuprinor 10 Transdermal Patch an opiate/ opiate blocker/ controlled substance/ pain killer/ addictive?

Zuprinor 10 Transdermal Patch belongs to a class of medications called opioid partial agonist-antagonists, which is used to relieve pain. It is a controlled substance and an addictive drug. Consult your doctor for alternate drug if you experience addiction

Does Zuprinor 10 Transdermal Patch block opiates?

Yes. Zuprinor 10 Transdermal Patch block opiates

Can Zuprinor 10 Transdermal Patch cause depression?

Zuprinor 10 Transdermal Patch is not known to cause depression. If you experience such side effects, please consult your doctor.

Fact Box

Chemical Class

Phenanthrene derivative

Habit Forming

Yes

Therapeutic Class

NEURO CNS

Action Class

Opioids- Partial agonist

Related lab tests

Opiates

References

Schumacher MA, Basbaum AI, Way WL. Opioids Analgesics & Antagonists. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 546-47.
Yaksh TL, WallaceIn MS. Opioids, Analgesia, and Pain Management. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 510.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 165-67.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:

Want to know more

We provide you with authentic, trustworthy and relevant information

Have issue with the content

Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135 || Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Zuprinor 10 Transdermal Patch

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Zuprinor Transdermal Patch

Benefits of Zuprinor Transdermal Patch

Side effects of Zuprinor Transdermal Patch

How to use Zuprinor Transdermal Patch

How Zuprinor Transdermal Patch works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Naltrexone (Oral Route)

Alprazolam (Oral Route)

Alprazolam (Injection Route)

Chlordiazepoxide (Oral Route)

Clobazam (Oral Route)

Frequently asked questions

What is Zuprinor 10 Transdermal Patch used for?

How to use Zuprinor 10 Transdermal Patch?

What precautions are to be taken while using Zuprinor 10 Transdermal Patch?

What should I avoid while using Zuprinor 10 Transdermal Patch?

Can I use one patch over another for better effect?

I am not able to stick Zuprinor 10 Transdermal Patch onto my skin, can I use tape to stick?

Can I take bath or shower while using Zuprinor 10 Transdermal Patch?

I feel dizzy when I get up from a sitting position or when I walk down the stairs. Is it due to Zuprinor 10 Transdermal Patch?

When to consult the doctor?

Can I use Zuprinor 10 Transdermal Patch during pregnancy?

Can I use Zuprinor 10 Transdermal Patch while breastfeeding?

How to safely store Zuprinor 10 Transdermal Patch?

Is Zuprinor 10 Transdermal Patch an opiate/ opiate blocker/ controlled substance/ pain killer/ addictive?

Does Zuprinor 10 Transdermal Patch block opiates?

Can Zuprinor 10 Transdermal Patch cause depression?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Opiates

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests