
Zulfy-O Plus Tablet
Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 21 Sep 2025 | 05:37 PM (IST)
Zulfy-O Plus Tablet is a combination medicine that is used to treat diarrhea and dysentery. It prevents the growth of microorganisms to treat bacterial infections. It also promotes the growth of good bacteria in the gut for proper digestion.
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General Information
The content is shown in English



Product introduction
Zulfy-O Plus Tablet is a prescription medicine that is to be taken as per the prescription or as suggested by the doctor. It should be taken with food, but it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The treatment must be completed even if you feel better.
Zulfy-O Plus Tablet may lead to some side effects such as nausea, headaches, dryness of mouth, etc. To overcome any such side effects, it is advised to eat a healthy balanced diet and drink plenty of fluid. Maintaining good oral hygiene can prevent or manage the dryness of the mouth. If any of the side effects get aggravated, contact your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must consult your doctor immediately.
Before taking this medicine, you should tell your doctor if you have any problems with your liver or kidneys. Also, tell your doctor if you are on any medication for any health condition. Pregnant or breastfeeding women should also consult with the doctors before taking it. Avoid drinking alcohol as it can cause excessive dizziness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. If you are a known allergic to the medicine, you must refrain from using this medicine and consult your doctor. It is advised to take proper rest during the course of treatment for the medicine to work effectively.
Zulfy-O Plus Tablet may lead to some side effects such as nausea, headaches, dryness of mouth, etc. To overcome any such side effects, it is advised to eat a healthy balanced diet and drink plenty of fluid. Maintaining good oral hygiene can prevent or manage the dryness of the mouth. If any of the side effects get aggravated, contact your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must consult your doctor immediately.
Before taking this medicine, you should tell your doctor if you have any problems with your liver or kidneys. Also, tell your doctor if you are on any medication for any health condition. Pregnant or breastfeeding women should also consult with the doctors before taking it. Avoid drinking alcohol as it can cause excessive dizziness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. If you are a known allergic to the medicine, you must refrain from using this medicine and consult your doctor. It is advised to take proper rest during the course of treatment for the medicine to work effectively.
Uses of Zulfy-O Plus Tablet
Benefits of Zulfy-O Plus Tablet
Treatment of Diarrhea
Diarrhea is a condition in which you frequently pass loose, watery stools. Zulfy-O Plus Tablet helps treat diarrhea by killing the bacteria causing infections as well as prevents them from multiplying. Zulfy-O Plus Tablet makes the stool less watery as well as reduces the frequency of loose motions. This helps you to stay well and do your daily activities without any problem. Zulfy-O Plus Tablet also restores the level of good bacteria in your stomach and thus prevents stomach upset due to the antibiotics. Since diarrhea causes loss of fluid from the body, drink plenty of fluids to make sure you stay hydrated.
Diarrhea is a condition in which you frequently pass loose, watery stools. Zulfy-O Plus Tablet helps treat diarrhea by killing the bacteria causing infections as well as prevents them from multiplying. Zulfy-O Plus Tablet makes the stool less watery as well as reduces the frequency of loose motions. This helps you to stay well and do your daily activities without any problem. Zulfy-O Plus Tablet also restores the level of good bacteria in your stomach and thus prevents stomach upset due to the antibiotics. Since diarrhea causes loss of fluid from the body, drink plenty of fluids to make sure you stay hydrated.
Treatment of Dysentery
Dysentery is a bacterial or parasitic infection in which you pass loose and watery stools with blood and mucus. You may have severe stomach cramps, nausea, and vomiting. Zulfy-O Plus Tablet works by stopping the growth of bacteria and parasites causing infection. It relieves these symptoms and also helps you to stay well by preventing them from coming back. In order to prevent the spread of infection, it is advisable to always wash your hands after using the toilet.
Dysentery is a bacterial or parasitic infection in which you pass loose and watery stools with blood and mucus. You may have severe stomach cramps, nausea, and vomiting. Zulfy-O Plus Tablet works by stopping the growth of bacteria and parasites causing infection. It relieves these symptoms and also helps you to stay well by preventing them from coming back. In order to prevent the spread of infection, it is advisable to always wash your hands after using the toilet.
Side effects of Zulfy-O Plus Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zulfy-O Plus
- Nausea
- Vomiting
- Stomach pain
- Loss of appetite
- Headache
- Dizziness
How to use Zulfy-O Plus Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zulfy-O Plus Tablet is to be taken with food.
How Zulfy-O Plus Tablet works
Zulfy-O Plus Tablet is a combination of three medicines: Ornidazole, Ofloxacin, and Lactobacillus.
Quick tips
- This combination medicine helps treat diarrhea and dysentery.
- Diarrhea can cause dehydration. Drink plenty of fluids to help rehydrate you. Consult your doctor if your diarrhea lasts for more than 48 hours.
- Do not use Zulfy-O Plus Tablet if you have blood in your stool or if you are severely constipated.
- It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
- Avoid consuming alcohol when taking this medicine as it may irritate your stomach and also cause excessive drowsiness.
- Notify your doctor if you feel pain in your tendons, numbness or tingling sensations.
- Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Zulfy-O Plus Tablet.

Pregnancy
CONSULT YOUR DOCTOR
Zulfy-O Plus Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Zulfy-O Plus Tablet during breastfeeding is not available. Please consult your doctor.

Driving
UNSAFE
Zulfy-O Plus Tablet may cause side effects which could affect your ability to drive.

Kidney
SAFE IF PRESCRIBED
Zulfy-O Plus Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Zulfy-O Plus Tablet may not be needed in these patients. Please consult your doctor.

Liver
CAUTION
Zulfy-O Plus Tablet should be used with caution in patients with liver disease. Dose adjustment of Zulfy-O Plus Tablet may be needed. Please consult your doctor.
Frequently asked questions
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.
No, do not stop taking Zulfy-O Plus Tablet and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.
Take Zulfy-O Plus Tablet as soon as you remember it. However, do not take it if it's almost time for your next dose. Also, do not take an extra dose to make up for your missed dose.
Fact Box
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Zodak Healthcare
Address: SCO-96, Basement, Sector-5, Panchkula (Haryana) India
Address: SCO-96, Basement, Sector-5, Panchkula (Haryana) India
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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