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ZosTER Cream

Acyclovir (5% w/w)

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ZosTER Cream is an antiviral medicine used for the treatment of herpes labialis (cold sores) and genital herpes infections caused by the herpes simplex virus. It helps reduce the growth and spread of the virus and helps in clearing the skin infection.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 07 Jan 2026 | 03:32 PM (IST)

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General Information

Contains

Acyclovir (5% w/w)

Marketer

Leeford Healthcare Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Use ZosTER Cream in the dose and duration as advised by your doctor. Clean and dry the affected area before applying the medicine. Wash your hands thoroughly before and after applying this medicine. Avoid touching or scratching the affected area, and keep the area clean and dry.

ZosTER Cream may cause mild burning, irritation, itching, and redness at the application site. These are usually temporary and resolve on their own. Consult your doctor if these side effects persist or worsen. Avoid applying other medicine on the treated area unless advised by your doctor.

ZosTER Cream is for external use only. Do not apply it to the eyes, inside the mouth, or on mucous membranes. Avoid sexual contact while sores are present to prevent transmission of the virus. Use with caution if you have a weakened immune system or kidney problems, and inform your doctor about all other medications you are using. Pregnant or breastfeeding women should consult their doctor before using this medicine.

Uses of ZosTER Cream

Benefits of ZosTER Cream

Treatment of Herpes labialis
ZosTER Cream helps heal cold sores (herpes labialis) faster and reduces pain, itching, and burning. It stops the virus from multiplying and shortens the outbreak, preventing it from worsening. This helps you feel more comfortable and improve your overall quality of life.

Treatment of Genital herpes infection
ZosTER Cream helps relieve pain, burning, and itching caused by genital herpes by preventing the virus from multiplying. It promotes faster healing of sores and helps reduce the risk of spreading the infection. Regular use as directed helps control flare-ups and provides relief from discomfort, allowing patients to manage the condition more effectively.

Side effects of ZosTER Cream

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of ZosTER

Application site reactions (burning, irritation, itching and redness)

How to use ZosTER Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

How ZosTER Cream works

ZosTER Cream is an antiviral medication which treats skin infections caused by Herpes simplex virus. It works by preventing the multiplication of virus in the skin cells. This stops the virus from producing new viruses and clears up your skin infection.

All substitutes for ZosTER Cream

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Treatment should be started as early as possible following onset of signs and symptoms.
Apply it thinly to affected area five times a day, or as suggested by your doctor.
Do not use it in the eyes, mouth, nose, or vagina as it may cause irritation. In case of accidental exposure, rinse immediately with plenty of water.
Do not touch the sores unnecessarily with your hands or towel, as that may spread the infection.
Inform your doctor if your symptoms have not improved after 10 days of treatment.

Safety advice

Alcohol

No interaction found/established

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of ZosTER Cream during pregnancy is not available. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

ZosTER Cream may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

Frequently asked questions

What is ZosTER Cream used for?

ZosTER Cream is used for treating herpes simplex infections of the skin and lips (cold sores, also called herpes labialis) and for initial genital herpes. It helps sores heal faster and reduces pain when used as directed.

When should I start applying medicine?

Start treatment as soon as you notice the first symptoms (tingling, itching, redness) or when a lesion appears. Early use gives the best chance of shortening the episode.

Will ZosTER Cream stop me from passing the virus to others?

ZosTER Cream can speed healing and reduce pain, but there are no data showing it helps prevent transmission. Avoid contact (kissing or sexual contact) while sores are present, and follow good hygiene to reduce spread.

Can I use ZosTER Cream on the genital area or inside the mouth?

No. The medicine is intended for use on the external lips and face for cold sores. Application to mucous membranes (inside the mouth, nose, eye, or genitals) is not recommended. Follow the product label or your doctor’s instructions.

Can I use it during pregnancy or while breastfeeding?

Topical use results in very low systemic exposure. Use during pregnancy or lactation should be considered only if the potential benefit justifies any possible risk. Discuss this with your doctor. If you have an active herpetic lesion on the breast, avoid nursing from the affected breast.

Fact Box

Chemical Class

Hypoxanthines

Habit Forming

Therapeutic Class

DERMA

Action Class

Antiviral Agents (Non-HIV)

Related lab tests

Herpes Simplex Virus 1 DNA PCR

Herpes Simplex Virus 1 IgG

Herpes Simplex Virus 2 DNA PCR

Herpes Simplex Virus 2 IgG

Herpes Simplex Virus 2 IgM

References

Acosta EP, Flexner C. Antiviral Agents (Nonretroviral). In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1594-1600.
Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 846-47.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 18-22.
Acyclovir [Prescribing Information]. Ontario, Canada: GlaxoSmithKline; 2014. [Accessed 09 Oct. 2025] (online) Available from:
Aciclovir [Summary of Product Characteristics]. Dublin 24, Ireland: Haleon Ireland Limited; 2025. [Accessed 09 Oct. 2025] (online) Available from:
Acyclovir [Prescribing Information]. Bedminster, NJ: Alembic Pharmaceuticals, Inc.; 2025.

User feedback

Patients taking ZosTER Cream

Once A Day

50%

Twice A Day

33%

Thrice A Day

17%

What are you using ZosTER Cream for?

Herpes labialis

44%

Genital herpes infection

22%

Shingles

11%

Others

11%

Herpes simplex virus infections

11%

How much was the improvement?

Poor

38%

Excellent

38%

Average

24%

What were the side-effects while using ZosTER Cream?

No Side Effect

75%

Dry skin

25%

How do you take ZosTER Cream?

With or without food

100%

Please rate ZosTER Cream on price

Expensive

53%

Average

33%

Not Expensive

13%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Leeford Healthcare Ltd
Address: 203, Mangalam, Kulupwadi, Borivali (E), Mumbai-400066

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver ZosTER Cream. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

ZosTER Cream

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of ZosTER Cream

Benefits of ZosTER Cream

Side effects of ZosTER Cream

How to use ZosTER Cream

How ZosTER Cream works

All substitutes for ZosTER Cream

Herpiford Cream

Herpex 5% Cream

Acivir Cream

Ocuvir Skin Cream

Primacort Plus Cream

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is ZosTER Cream used for?

When should I start applying medicine?

Will ZosTER Cream stop me from passing the virus to others?

Can I use ZosTER Cream on the genital area or inside the mouth?

Can I use it during pregnancy or while breastfeeding?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Herpes Simplex Virus 1 DNA PCR

Herpes Simplex Virus 1 IgG

Herpes Simplex Virus 2 DNA PCR

Herpes Simplex Virus 2 IgG

Herpes Simplex Virus 2 IgM

References

User feedback

Patients taking ZosTER Cream

What are you using ZosTER Cream for?

How much was the improvement?

What were the side-effects while using ZosTER Cream?

How do you take ZosTER Cream?

Please rate ZosTER Cream on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests