Zoftafic 1gm Injection

Reviewed By Dr. Mekhala Chandra, MD, MBBS

Last updated on 15 Apr 2026 | 05:17 PM (IST)

Zoftafic 1gm Injection is an antibiotic belonging to the carbapenem group that fights bacteria. It is used to treat severe infections of the skin, lungs, stomach, urinary tract, blood and brain (eg. meningitis). It works by killing the bacteria that cause these problems.

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Stored between 2-8°C

₹290 MRP ₹328.1312% off

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General Information

Contains

Ertapenem (1000mg)

Marketer

Pacific Meditech Pvt Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Zoftafic 1gm Injection is commonly used to treat seriously ill patients admitted to the hospital. This medicine is given by drip or by direct injection into a vein, under the supervision of a doctor or a nurse. The dose will depend on what type of infection you have, where it is in the body, and how serious it is. You should keep on taking the injection for as long as you have been prescribed, even if your symptoms quickly improve. If you stop taking it too early the infection may return or worsen.

Some people may develop side effects like diarrhea, nausea, headache, infused vein complication. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or will not go away.

Before starting treatment with this medicine, you should tell your doctor if you have epilepsy, liver, or kidney problems or if you are allergic to any antibiotic. While using it, you may be advised blood tests to monitor your blood cell counts and kidney function. This medicine is generally regarded as safe to use in pregnancy and breastfeeding if prescribed by your doctor.

Uses of Zoftafic Injection

Severe bacterial infections

Benefits of Zoftafic Injection

Severe bacterial infections
Zoftafic 1gm Injection works by killing bacteria which can cause serious infections. It is a versatile medicine used to treat many different types of bacterial infections such as infections of the brain (meningitis), lungs (pneumonia), abdomen, urinary tract, skin, blood, and heart. This medicine is usually given as an injection by a doctor or nurse.

Zoftafic 1gm Injection usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Zoftafic Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zoftafic

Insomnia (difficulty in sleeping)
Infusion site reaction
Edema (swelling)
Abdominal pain
Disorientation (alteration of mental status)
Vaginal inflammation
Arrhythmia (irregular heartbeats)
Infusion site inflammation
Headache
Vomiting
Diarrhea
Rash
Dizziness
Breathlessness
Nausea

How to use Zoftafic Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Zoftafic Injection works

Zoftafic 1gm Injection is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.

All substitutes for Zoftafic 1gm Injection

For information purposes only. Consult a doctor before taking any medicine.

Cedapenem 1000mg Injection

by Samarth Life Sciences Pvt Ltd

₹4026.56/injection

1127% costlier

Quick tips

Zoftafic 1gm Injection is an antibiotic that's usually only given in the hospital for serious infections.
It is given by a drip into a vein (intravenous infusion) over 20 to 60 minutes.
Inform your doctor if you are allergic to penicillin or if you are taking any seizure medication before starting treatment with this medication.
Diarrhea may occur as a side effect. Inform your doctor if you develop severe stomach pain or if you find blood in your stools.
Your doctor may monitor your liver and kidney function while you are having treatment with this medication.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Zoftafic 1gm Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Zoftafic 1gm Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

SAFE IF PRESCRIBED

Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.

Driving

UNSAFE

Zoftafic 1gm Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Certain side effects, such as dizziness and sleepiness, have been reported with Zoftafic 1gm Injection, which may affect some patients’ ability to drive or operate machinery

Kidney

CAUTION

Zoftafic 1gm Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

SAFE IF PRESCRIBED

Zoftafic 1gm Injection is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Zoftafic with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not consume Cholera Vaccine (Inactivated) two weeks before and at least 10 days after consuming Ertapenem. Please consult your doctor. Ertapenem may reduce the efficacy of Cholera Vaccine (Inactivated).

Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Ertapenem may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine. Ertapenem may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine.

Moderate

Phenindione (Oral Route)

Your doctor may monitor your blood coagulation status and adjust the dose of Phenindione accordingly.

Moderate

Warfarin (Oral Route)

Your doctor may monitor your blood coagulation status and adjust the dose of Warfarin accordingly.

Mild

Acenocoumarol (Oral Route)

Your doctor may monitor your blood coagulation status and adjust the dose of Acenocoumarol accordingly.

Frequently asked questions

What if I cannot tolerate Zoftafic 1gm Injection?

It is common to have minor side effects such as nausea, vomiting, diarrhea and headache but generally these settle down. If these symptoms trouble you, contact your doctor. Your doctor may prescribe an alternative medicine to help you get rid of these symptoms. Serious side effects occur in very rare cases. But, if you experience any serious complication, seek immediate medical advice.

What is drug resistance? Is it possible to develop resistance to Zoftafic 1gm Injection?

Drug resistance is a condition in which the bacteria gets modified in your body and stops reacting to the medicine. Because of this, the medicine stops working. Resistance to Zoftafic 1gm Injection is not very common at least for the bacteria against which it works.

Does Zoftafic 1gm Injection have any effect on blood sugar levels if taken to treat infections of diabetic foot?

Rare reports suggest that Zoftafic 1gm Injection may decrease the blood sugar levels, but this medicine does not affect the blood sugar levels in everyone. However, it is important to keep monitoring your blood sugar levels regularly. Consult your doctor if you experience any sudden dip in blood sugar levels.

Is Zoftafic 1gm Injection safe to be used in children?

Safety of Zoftafic 1gm Injection in children less than 3 months of age has not yet been assessed. However, the side effects and effectivity of Zoftafic 1gm Injection in children beyond the age of 3 months is almost similar when compared with adults.

I feel better now. Can I stop taking Zoftafic 1gm Injection?

No. Make sure to receive all doses your doctor has prescribed, even if you feel better. This is because your symptoms may have improved but chances are that the infection is still present in your body. Skipping doses can increase the risk of developing an infection that is resistant to medication. So, continue taking Zoftafic 1gm Injection as prescribed. After you have finished all the doses, your doctor may advise you on some tests to make sure your infection has completely cleared up.

Fact Box

Chemical Class

Thienamycins

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Carbapenems

Related lab tests

Complete Blood Count

References

Petri WA Jr. Penicillins, Cephalosporins, and Other β -Lactam Antibiotics. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1500.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 490-91.
Ertapenem. Whitehouse Station, New Jersey: Merck and Co., Inc.; 2001 [revised Feb. 2012]. [Accessed 01 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
Ertapenem sodium. Schaumburg, IL: SAGENT Pharmaceuticals; 2026. [Accessed 15 Apr. 2026] (online). Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Pacific Meditech Pvt Ltd
Address: Office No - 3, Plot No B-64, Kh No - 371, Bawana Road Shahbad Daulatpur North West DL 110042 INDIA

Vendor Details

Country of origin: India

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