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Ertapenem

INFORMATION

Uses

Ertapenem is used in serious bacterial infections and prevention of infection after surgery of the colon or rectum.

How it works

Ertapenem is an antibiotic. It kills the bacteria by attacking their cell wall. Specifically, it prevents the synthesis of a substance in the cell wall called peptidoglycan, which provides the cell wall with the strength required for survival of bacteria in human body.

Common side effects

Vomiting, Nausea, Application site burning, Application site redness of skin, Application site irritation, Confusion, Cough, Dizziness, Vagina dryness, Headache, Insomnia, Stomach pain, Irritation in urethra, Vaginal burning sensation, Vaginal itching, Irritation in vagina, Pain in vagina, Pain in urethra, Burning sensation in urethra, Constipation, Diarrhoea, Chills, Fever

AVAILABLE MEDICINE

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Expert advice

  • Do not start ertapenem, if you are allergic to ertapenem, or to any of the other ingredients in ertapenem tablets, or other antibiotics such as penicillins, cephalosporins or carbapenems.
  • Do not take ertapenem, if you have developed diarrhea just before or after taking ertapenem.
  • Doctor’s advice should be considered in case of patients with following history of disease conditions: kidney disease (especially if you are receiving dialysis treatments), localized tremors, or fits; high blood pressure or other diseases.
  • Avoid using ertapenem, if you are pregnant, planning to become pregnant, or breast-feeding.

Frequently asked questions

Ertapenem

Q.Is ertapenem and penicillin or a sulfa drug or a beta lactam or does ertapenem contain penicillin?
Ertapenem is an antibiotic of the beta-lactam group, similar in structure to penicillins. However, they are used for the treatment of different infections. Ertapenem is not a sulfa drug

Q.what is ertapenem used for?
Ertapenem is used to treat infections in various parts of the body caused by bacteria that are susceptible it. These include gynecologic and abdominal infections, pneumonia, skin and underlying tissue infections due to diabetes (e.g. diabetic foot). It is also used to prevent infection after certain types of surgeries

Q.What is ertapenem sodium?
Ertapenem sodium is sodium salt of the ertapenem antibiotic

Q.Is ertapenem nephrotoxic?
Yes. It increases serum creatinine and serum urea

Q.What is ertapenem IV?
Ertapenem IV is intravenous preparation of ertapenem i.e. solution of ertapenem that is used for direct injection into a blood vessel (vein) over few minutes or hours

Q.Does ertapenem cover enterococcus or enterococcus faecalis or pseudomonas?
No, ertapenem is not effective against enterococcus or enterococcus faecalis and pseudomonas at all

Q.Does ertapenem cover VRE or ESBL or MSSA?
Ertapenem covers ESBL (extended spectrum beta lactamase) producing bacteria as well as MSSA (methicillin sensitive staphylococcus aureus). It does not cover and is ineffective to treat VRE (vancomycin resistant enterococci)

Q.Is ertapenem compatible with d5w?
Ertapenem is not compatible with dextrose 5% injection solution

Q.Is ertapenem a vesicant?
Ertapenem is not a vesicant. However, leakage of the ertapenem solution during injection can cause pain and swelling of the surrounding skin and underlying tissue, as well as skin ulceration.


Content on this page was last updated on 24 November, 2016, by Dr. Varun Gupta (MD Pharmacology)