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Zithrozem 250 Tablet

Azithromycin (250mg)
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Zithrozem 250 Tablet is an antibiotic used to treat various types of bacterial infections of the respiratory tract, ear, nose, throat, lungs, skin, and eye in adults and children. It is also effective in typhoid fever and some sexually transmitted diseases like gonorrhea.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 22 May 2026 | 06:22 PM (IST)
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General Information

The content is shown in English
Zithrozem 250 Tablet image
Zithrozem 250 Tablet image

Product introduction

Zithrozem 250 Tablet can be taken with or without food. Take it regularly and at a fixed time. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the return or worsening of the infection.


Common side effects seen with Zithrozem 250 Tablet include diarrhea, vomiting, nausea, and stomach pain. These are usually temporary and subside with the completion of treatment. Consult your doctor if you find these side effects worry you or persist for a longer duration.


Do not use Zithrozem 250 Tablet if you have a history of cholestatic jaundice or hepatic dysfunction that can be worsened with the use of Zithrozem 250 Tablet. Inform your doctor if you have any previous history of allergies or heart problems before taking this medicine. Pregnant or breastfeeding women should consult their doctor before using this medicine.

Uses of Zithrozem Tablet

  • Treatment of Bacterial infections : Zithrozem 250 Tablet is used to treat a wide range of bacterial infections, including infections of the respiratory tract (such as pneumonia and bronchitis), sinus (sinusitis), ear (otitis media), skin and soft tissues, and certain sexually transmitted infections.

Benefits of Zithrozem Tablet

Treatment of Bacterial infections
Zithrozem 250 Tablet is an antibiotic used to treat bacterial infections in different parts of the body. It works by stopping the growth of bacteria, helping the body clear the infection effectively. This helps reduce symptoms such as fever, pain, swelling, or difficulty breathing, depending on the site of infection. Complete the full course as prescribed to help prevent the infection from returning and to reduce the risk of antibiotic resistance.

Side effects of Zithrozem Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zithrozem
  • Diarrhea
  • Nausea
  • Abdominal pain

How to use Zithrozem Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zithrozem 250 Tablet may be taken with or without food.

How Zithrozem Tablet works

Zithrozem 250 Tablet is an antibiotic that works by inhibiting bacterial protein synthesis. It binds to the bacterial ribosome and prevents the production of essential proteins required for bacterial growth and survival, thereby stopping the infection from spreading.

Quick tips

  • Take Zithrozem 250 Tablet exactly as prescribed and complete the full course, even if you start feeling better.
  • Stopping Zithrozem 250 Tablet early may allow the infection to return and become harder to treat.
  • Take Zithrozem 250 Tablet at the same time each day to maintain consistent antibiotic levels in the body.
  • Avoid taking antacids within 2 hours before or after taking Zithrozem 250 Tablet, as they may affect absorption.
  • Take Zithrozem 250 Tablet with food, or it may cause stomach upset.
  • Diarrhea may occur while taking Zithrozem 250 Tablet; stay hydrated and contact your doctor if it becomes severe.
  • Stop taking Zithrozem 250 Tablet and seek immediate medical help if you develop rash, swelling of the face or throat, or difficulty breathing.
  • Inform your doctor if you have liver disease or a history of heart rhythm problems before taking Zithrozem 250 Tablet.
  • Report symptoms such as palpitations, fainting, or severe dizziness promptly to your doctor.
  • Consult your doctor if symptoms do not improve within a few days or if they worsen.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Zithrozem 250 Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Zithrozem 250 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
There may be a possibility of diarrhea or rash in the baby.
Driving

Driving

SAFE
Zithrozem 250 Tablet does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Zithrozem 250 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Zithrozem 250 Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Zithrozem with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Domperidone (Oral Route)

Do not consume Domperidone with Azithromycin.
Severe

Amiodarone (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Amiodarone (Injection Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Artemether (Injection Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Artemether (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Frequently asked questions

Zithrozem 250 Tablet is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
You should inform your doctor if you do not notice any improvement in your symptoms after 3 days of taking Zithrozem 250 Tablet. Also, if your symptoms get worse, inform your doctor immediately.
Yes, the use of Zithrozem 250 Tablet can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If you are experiencing severe diarrhea, talk to your doctor about it.
Zithrozem 250 Tablet is usually prescribed once daily. You can take it at any time of the day, but remember to take it at the same time each day. The medicine should be taken 1 hour before meals or 2 hours after eating food. You can take the tablet preparation with or without food. However, you must take Zithrozem 250 Tablet exactly as advised by your doctor and ask your doctor if you have any doubts.
Usually, Zithrozem 250 Tablet starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.
The duration of treatment depends on the type of infection being treated and the age of the patient. Zithrozem 250 Tablet is not necessarily given for 3 days. In most bacterial infections, a single dose of 500 mg is given for 3 days. Alternatively, it can be given as 500 mg once on day 1 and then 250 mg once from day 2 to day 5. In some cases of infection such as genital ulcer disease, it is given as a single 1 gram dose. Therefore, you must stick to the regimen advised by your doctor.
Generally, it is recommended that patients taking Zithrozem 250 Tablet should avoid taking any antacid with this medicine as this can affect the overall effectiveness of Zithrozem 250 Tablet. It is also recommended to avoid exposure to sunlight or tanning beds as Zithrozem 250 Tablet increases the risk of sunburn.
Zithrozem 250 Tablet is an effective antibiotic that is used for the treatment of many bacterial infections. Compared to other antibiotics, Zithrozem 250 Tablet has a longer half-life which means that it stays in the body for a long time because of which it is given once a day and for a short span of time. Other antibiotics comparatively have a shorter half-life and are usually given twice, thrice, or four times a day.
Some people may get a fungal or yeast infection known as thrush after taking Zithrozem 250 Tablet. Antibiotics such as Zithrozem 250 Tablet can kill the normal or ‘good bacteria’ of your intestine responsible for preventing thrush. You should inform your doctor if you get a sore or vaginal itching or discharge. Also, inform your doctor if you get a white patch in the mouth or tongue after taking Zithrozem 250 Tablet or soon after stopping it.

Fact Box

Chemical Class

Macrolides

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Macrolides

References

  1. Chambers HF, Deck DH. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidiones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 801.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 117-20.
  3. Azithromycin [EMC Label]. Frimley, Camberley: Sandoz Ltd.; 2018. [Accessed 31 Mar. 2019] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 31 Mar. 2019] (online) Available from:
  5. Azithromycin [Prescribing Information]. Panchmahal, Gujarat: Alembic Pharmaceuticals Limited; 2019. [Accessed 09 Jun, 2023] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zeelab Pharmacy Pvt Ltd
Address: 913, D-104, Pitampura, Delhi-110034

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Zithrozem 250 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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