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Zithium 500 Tablet

Azithromycin (500mg)

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Zithium 500 Tablet is an antibiotic used to treat various types of bacterial infections of the respiratory tract, ear, nose, throat, lungs, skin, and eye in adults and children. It is also effective in typhoid fever and some sexually transmitted diseases like gonorrhea.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 06 May 2026 | 05:19 PM (IST)

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General Information

Contains

Azithromycin (500mg)

Marketer

Alkem Laboratories Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Zithium 500 Tablet can be taken with or without food. Take it regularly and at a fixed time. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the return or worsening of the infection.

Common side effects seen with Zithium 500 Tablet include diarrhea, vomiting, nausea, and stomach pain. These are usually temporary and subside with the completion of treatment. Consult your doctor if you find these side effects worry you or persist for a longer duration.

Do not use Zithium 500 Tablet if you have a history of cholestatic jaundice or hepatic dysfunction that can be worsened with the use of Zithium 500 Tablet. Inform your doctor if you have any previous history of allergies or heart problems before taking this medicine. Pregnant or breastfeeding women should consult their doctor before using this medicine.

Uses of Zithium Tablet

Treatment of Bacterial infections : Zithium 500 Tablet is used to treat a wide range of bacterial infections, including infections of the respiratory tract (such as pneumonia and bronchitis), sinus (sinusitis), ear (otitis media), skin and soft tissues, and certain sexually transmitted infections.

Benefits of Zithium Tablet

Treatment of Bacterial infections
Zithium 500 Tablet is an antibiotic used to treat bacterial infections in different parts of the body. It works by stopping the growth of bacteria, helping the body clear the infection effectively. This helps reduce symptoms such as fever, pain, swelling, or difficulty breathing, depending on the site of infection. Complete the full course as prescribed to help prevent the infection from returning and to reduce the risk of antibiotic resistance.

Side effects of Zithium Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zithium

Diarrhea
Nausea
Abdominal pain

How to use Zithium Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zithium 500 Tablet may be taken with or without food.

How Zithium Tablet works

Zithium 500 Tablet is an antibiotic that works by inhibiting bacterial protein synthesis. It binds to the bacterial ribosome and prevents the production of essential proteins required for bacterial growth and survival, thereby stopping the infection from spreading.

All substitutes for Zithium 500 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Take Zithium 500 Tablet exactly as prescribed and complete the full course, even if you start feeling better.
Stopping Zithium 500 Tablet early may allow the infection to return and become harder to treat.
Take Zithium 500 Tablet at the same time each day to maintain consistent antibiotic levels in the body.
Avoid taking antacids within 2 hours before or after taking Zithium 500 Tablet, as they may affect absorption.
Take Zithium 500 Tablet with food, or it may cause stomach upset.
Diarrhea may occur while taking Zithium 500 Tablet; stay hydrated and contact your doctor if it becomes severe.
Stop taking Zithium 500 Tablet and seek immediate medical help if you develop rash, swelling of the face or throat, or difficulty breathing.
Inform your doctor if you have liver disease or a history of heart rhythm problems before taking Zithium 500 Tablet.
Report symptoms such as palpitations, fainting, or severe dizziness promptly to your doctor.
Consult your doctor if symptoms do not improve within a few days or if they worsen.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Zithium 500 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Zithium 500 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

SAFE IF PRESCRIBED

Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
There may be a possibility of diarrhea or rash in the baby.

Driving

SAFE

Zithium 500 Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Zithium 500 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Zithium 500 Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Zithium with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Domperidone (Oral Route)

Do not consume Domperidone with Azithromycin.

Severe

Amiodarone (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Severe

Amiodarone (Injection Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Severe

Artemether (Injection Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Severe

Artemether (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Frequently asked questions

Is Zithium 500 Tablet safe?

Zithium 500 Tablet is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

What if I don't get better?

You should inform your doctor if you do not notice any improvement in your symptoms after 3 days of taking Zithium 500 Tablet. Also, if your symptoms get worse, inform your doctor immediately.

Can the use of Zithium 500 Tablet cause diarrhea?

Yes, the use of Zithium 500 Tablet can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If you are experiencing severe diarrhea, talk to your doctor about it.

Can Zithium 500 Tablet be taken at night?

Zithium 500 Tablet is usually prescribed once daily. You can take it at any time of the day, but remember to take it at the same time each day. The medicine should be taken 1 hour before meals or 2 hours after eating food. You can take the tablet preparation with or without food. However, you must take Zithium 500 Tablet exactly as advised by your doctor and ask your doctor if you have any doubts.

How long does Zithium 500 Tablet takes to work?

Usually, Zithium 500 Tablet starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.

Why is Zithium 500 Tablet given for 3 days?

The duration of treatment depends on the type of infection being treated and the age of the patient. Zithium 500 Tablet is not necessarily given for 3 days. In most bacterial infections, a single dose of 500 mg is given for 3 days. Alternatively, it can be given as 500 mg once on day 1 and then 250 mg once from day 2 to day 5. In some cases of infection such as genital ulcer disease, it is given as a single 1 gram dose. Therefore, you must stick to the regimen advised by your doctor.

What should I avoid while taking Zithium 500 Tablet?

Generally, it is recommended that patients taking Zithium 500 Tablet should avoid taking any antacid with this medicine as this can affect the overall effectiveness of Zithium 500 Tablet. It is also recommended to avoid exposure to sunlight or tanning beds as Zithium 500 Tablet increases the risk of sunburn.

Is Zithium 500 Tablet a strong antibiotic?

Zithium 500 Tablet is an effective antibiotic that is used for the treatment of many bacterial infections. Compared to other antibiotics, Zithium 500 Tablet has a longer half-life which means that it stays in the body for a long time because of which it is given once a day and for a short span of time. Other antibiotics comparatively have a shorter half-life and are usually given twice, thrice, or four times a day.

Can you get a yeast infection from taking Zithium 500 Tablet?

Some people may get a fungal or yeast infection known as thrush after taking Zithium 500 Tablet. Antibiotics such as Zithium 500 Tablet can kill the normal or ‘good bacteria’ of your intestine responsible for preventing thrush. You should inform your doctor if you get a sore or vaginal itching or discharge. Also, inform your doctor if you get a white patch in the mouth or tongue after taking Zithium 500 Tablet or soon after stopping it.

Fact Box

Chemical Class

Macrolides

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Macrolides

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

Chambers HF, Deck DH. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidiones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 801.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 117-20.
Azithromycin [EMC Label]. Frimley, Camberley: Sandoz Ltd.; 2018. [Accessed 31 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 31 Mar. 2019] (online) Available from:
Azithromycin [Prescribing Information]. Panchmahal, Gujarat: Alembic Pharmaceuticals Limited; 2019. [Accessed 09 Jun, 2023] (online) Available from:

User feedback

Patients taking Zithium 500 Tablet

Once A Day

70%

Twice A Day

20%

Twice A Week

Thrice A week

What are you using Zithium Tablet for?

Bacterial infections

86%

Typhoid fever

14%

How much was the improvement?

Poor

40%

Average

33%

Excellent

27%

What were the side-effects while using Zithium 500 Tablet?

No Side Effect

80%

Abdominal pain

20%

How do you take Zithium Tablet?

With food

100%

Please rate Zithium 500 Tablet on price

Not Expensive

58%

Average

42%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Alkem Laboratories Ltd
Address: Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Zithium 500 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Zithium 500 Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Zithium Tablet

Benefits of Zithium Tablet

Side effects of Zithium Tablet

How to use Zithium Tablet

How Zithium Tablet works

All substitutes for Zithium 500 Tablet

Azimax 500 Tablet

Azikem 500mg Tablet

Azax 500 Tablet

Zithrolect 500 Tablet

Azicip 500 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Domperidone (Oral Route)

Amiodarone (Oral Route)

Amiodarone (Injection Route)

Artemether (Injection Route)

Artemether (Oral Route)

Frequently asked questions

Is Zithium 500 Tablet safe?

What if I don't get better?

Can the use of Zithium 500 Tablet cause diarrhea?

Can Zithium 500 Tablet be taken at night?

How long does Zithium 500 Tablet takes to work?

Why is Zithium 500 Tablet given for 3 days?

What should I avoid while taking Zithium 500 Tablet?

Is Zithium 500 Tablet a strong antibiotic?

Can you get a yeast infection from taking Zithium 500 Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

User feedback

Patients taking Zithium 500 Tablet

What are you using Zithium Tablet for?

How much was the improvement?

What were the side-effects while using Zithium 500 Tablet?

How do you take Zithium Tablet?

Please rate Zithium 500 Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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