Ziglim Plus 2 Tablet SR is a combination medicine that helps control blood sugar levels. This medicine is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. It helps in proper utilisation of insulin, thereby lowering the blood sugar levels.

Ziglim Plus 2 Tablet SR should be taken in the dose and duration as advised by your doctor. It must be taken with food to avoid stomach upset. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. Overdose may lead to low blood sugar (hypoglycemia).

Some people may develop hypoglycemia (low blood sugar level) when this medicine is taken along with other antidiabetic medicines, alcohol or upon skipping a meal. Monitor your blood sugar levels regularly while taking it. Other common side effects of this medicine include nausea, taste changes, diarrhea, stomach pain, headache, edema (swelling), blurred vision, bone fracture, and respiratory tract infection.

Before taking this medicine, inform your doctor if you have any kidney, liver or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects.

Uses of Ziglim Plus Tablet SR

Treatment of Type 2 diabetes mellitus

Benefits of Ziglim Plus Tablet SR

In Treatment of Type 2 diabetes mellitus

Ziglim Plus 2 Tablet SR is a medicine that helps to control high blood glucose (sugar) levels. It helps get rid of extra glucose from your body through urine. It also improves the body’s response to the hormone insulin, which is responsible for regulating blood glucose (sugar) levels in our body. The insulin helps to lower your blood glucose levels and prevents them from rising after taking meals. You should keep taking it for as long as it is prescribed.
Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Side effects of Ziglim Plus Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ziglim Plus

Hypoglycemia (low blood glucose level)
Dizziness
Headache
Nausea
Vomiting
Diarrhea
Flatulence
Bronchitis (inflammation of the airways)
Anemia (low number of red blood cells)
Edema (swelling)

How to use Ziglim Plus Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ziglim Plus 2 Tablet SR is to be taken with food.

How Ziglim Plus Tablet SR works

Ziglim Plus 2 Tablet SR is a combination of three antidiabetic medicines: Glimepiride, Metformin and Pioglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Pioglitazone is a thiazolidinedione which further increases insulin sensitivity.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Ziglim Plus 2 Tablet SR.

Pregnancy

CONSULT YOUR DOCTOR

Ziglim Plus 2 Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Ziglim Plus 2 Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

CAUTION

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

Kidney

CAUTION

Ziglim Plus 2 Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Ziglim Plus 2 Tablet SR may be needed. Please consult your doctor.
Use of Ziglim Plus 2 Tablet SR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.

Liver

CAUTION

Ziglim Plus 2 Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Ziglim Plus 2 Tablet SR may be needed. Please consult your doctor.
Use of Ziglim Plus 2 Tablet SR is not recommended in patients with severe liver disease.

What if you forget to take Ziglim Plus Tablet SR?

If you miss a dose of Ziglim Plus 2 Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Ziglim Plus 2 Tablet SR

₹7.7/Tablet SR

Pioplus 2 Tablet SR

Systopic Laboratories Pvt Ltd

₹6.1/tablet sr

21% cheaper

Triglynase 2 Tablet SR

USV Ltd

₹7.85/tablet sr

2% costlier

Trigli 2 Tablet SR

Ordain Health Care Global Pvt Ltd

₹11.01/tablet sr

43% costlier

Triglimiprex 2 Tablet SR

Aristo Pharmaceuticals Pvt Ltd

₹12.5/tablet sr

62% costlier

Triopil 2 Tablet SR

Aristo Pharmaceuticals Pvt Ltd

₹12.5/tablet sr

62% costlier

View all substitutes

Quick tips

Take it with food to lower your chance of having an upset stomach.
It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Fact Box

Habit Forming

Therapeutic Class

ANTI DIABETIC

Patient concerns

I use ziglim plus 2. 2 tablets a day for last 4 years.It appears that the medicine not working Suggest alternate medicine.Blood test recent reading 140 fasting.257 pp.

Dr. Sanjay Bhatt

Physician

Need to increase some dose of medicine you are taking. Also take more Precautions to your diet. So discuss with your doctor

Diabetes mellitus type 2 ,thirst

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

User feedback

Patients taking Ziglim Plus 2 Tablet SR

Once A Day

100%

What are you using Ziglim Plus Tablet SR for?

Type 2 diabet*

100%

*Type 2 diabetes mellitus

How much was the improvement?

Average

40%

Poor

33%

Excellent

27%

What were the side-effects while using Ziglim Plus 2 Tablet SR?

No Side Effec*

50%

Taste change

25%

Hypoglycemia *

25%

*No Side Effect, Hypoglycemia (low blood glucose level)

How do you take Ziglim Plus Tablet SR?

Empty stomach

50%

With or witho*

25%

With food

25%

*With or without food

Please rate Ziglim Plus 2 Tablet SR on price

Average

42%

Expensive

33%

Not Expensive

25%

FAQs

Q. Can I drink alcohol while taking Ziglim Plus 2 Tablet SR?

No, it is not safe to drink alcohol while using Ziglim Plus 2 Tablet SR. Drinking alcohol may lower your blood sugar levels (hypoglycemia). Also, it can increase the chances of lactic acidosis.

Q. What should I inform the doctor before taking Ziglim Plus 2 Tablet SR?

Before taking Ziglim Plus 2 Tablet SR inform your doctor if you have congestive heart failure, kidney problems, liver problems, swelling of the back of the eye. Inform the doctor if you are pregnant, breastfeeding or a premenopausal woman. Let the doctor know if you are taking any prescription and non-prescription medicines, vitamins, and herbal supplements.

Q. Can the use of Ziglim Plus 2 Tablet SR lead to Vitamin B12 deficiency?

Yes, the use of Ziglim Plus 2 Tablet SR can cause vitamin B12 deficiency as it contains metformin in it. On long-term use, it interferes with absorption of vitamin B12 in the stomach.

Q. Can the use of Ziglim Plus 2 Tablet SR cause hypoglycemia?

Yes, the use of Ziglim Plus 2 Tablet SR can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your meal, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always carry some sugary item like a candy or chocolate with you.

Q. What are the instructions for the storage and disposal of Ziglim Plus 2 Tablet SR?

Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

Top Diabetologists

4.9 ★

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Dr. Yuvraj Arora Monga

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Glimepiride. North Harrow, Middlesex: Accord Healthcare Limited; 2008 [revised 24 Jul. 2014]. [Accessed 08 Apr. 2019] (online) Available from:
Metformin hydrochloride oral solution. Gloversville, New York: Ranbaxy Pharmaceuticals Inc.; 2003. [Accessed 08 Apr. 2019] (online) Available from:
Pioglitazone hydrochloride. Wooburn Green, High Wycombe: Takeda UK Ltd.; 2000 [revised 13 Sep. 2018]. [Accessed 08 Apr. 2019] (online) Available from:
Metformin Hydrochloride SR, Pioglitazone Hydrochloride and Glimepiride Tablets [Prescribing Information]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd.; 2016. [Accessed 27 Oct. 2021] (online) Available from:
American Diabetes Association. 14. Management of Diabetes in Pregnancy: Standards of Medical Care in Diabetes-2021. Diabetes Care. 2021;44(Suppl 1): S200-S210. [Accessed 20 Sept. 2021] (online) Available from:

Manufacturer/Marketer address

FDC LIMITED, B-8, MIDC Area, Waluj - 431 136, Dist. Aurangabad, Maharashtra

Country of origin: India
Expires on or after: June, 2023

A licensed vendor partner from your nearest location will deliver Ziglim Plus 2 Tablet SR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.