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Triglynase 2 Tablet SR

Glimepiride (2mg)+ Metformin (500mg)+ Pioglitazone (15mg)

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Triglynase 2 Tablet SR is a medicine that helps control blood sugar levels. This medicine is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. It helps in the proper utilisation of insulin, thereby lowering the blood sugar levels.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 01 Apr 2026 | 02:33 PM (IST)

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10 tablet sr

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General Information

Contains

Glimepiride (2mg)+ Metformin (500mg)+ Pioglitazone (15mg)

Marketer

USV Private Limited

Storage

Store below 25°C

The content is shown in English

Product introduction

Triglynase 2 Tablet SR should be taken in the dose and duration as advised by your doctor. It must be taken with food to avoid stomach upset. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. Overdose may lead to low blood sugar (hypoglycemia).

Some people may develop hypoglycemia (low blood sugar level) when this medicine is taken along with other antidiabetic medicines, alcohol, or upon skipping a meal. Monitor your blood sugar levels regularly while taking it. Other common side effects of this medicine include back pain, chest pain, headache, and respiratory tract infections.

Before taking this medicine, inform your doctor if you have any kidney, liver or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects.

Uses of Triglynase Tablet SR

Treatment of Type 2 diabetes mellitus

Benefits of Triglynase Tablet SR

Treatment of Type 2 diabetes mellitus
Type 2 diabetes is a condition where the body either does not produce enough insulin or cannot use it properly, leading to high blood sugar levels. Triglynase 2 Tablet SR helps improve blood sugar control by supporting better use of insulin and reducing excess glucose levels in the body. It helps maintain more stable sugar levels throughout the day, lowers the risk of diabetes-related complications, and supports overall metabolic health when used along with a proper diet and lifestyle.

Side effects of Triglynase Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Triglynase

Cardiac disturbances
Pain in extremity
Back pain
Chest pain
Headache
Sinus inflammation
Muscle pain
Sore throat

How to use Triglynase Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Triglynase 2 Tablet SR should be taken with or after food.

How Triglynase Tablet SR works

Triglynase 2 Tablet SR is a combination of three antidiabetic medicines: Glimepiride, Metformin and Pioglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Pioglitazone is a thiazolidinedione which further increases insulin sensitivity.

All substitutes for Triglynase 2 Tablet SR

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Take it with food to lower your chance of having an upset stomach.
It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Triglynase 2 Tablet SR

Pregnancy

UNSAFE

Triglynase 2 Tablet SR is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Triglynase 2 Tablet SR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Triglynase 2 Tablet SR may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Triglynase 2 Tablet SR should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Triglynase 2 Tablet SR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.

Liver

UNSAFE

Triglynase 2 Tablet SR is unsafe to use in patients with liver disease and should be avoided.
Use of Triglynase 2 Tablet SR is not recommended in patients with severe liver disease.

Frequently asked questions

Can I drink alcohol while taking Triglynase 2 Tablet SR?

No, it is not safe to drink alcohol while using Triglynase 2 Tablet SR. Drinking alcohol may lower your blood sugar levels (hypoglycemia). Also, it can increase the chances of lactic acidosis.

What should I inform the doctor before taking Triglynase 2 Tablet SR?

Before taking Triglynase 2 Tablet SR inform your doctor if you have congestive heart failure, kidney problems, liver problems, swelling of the back of the eye. Inform the doctor if you are pregnant, breastfeeding or a premenopausal woman. Let the doctor know if you are taking any prescription and non-prescription medicines, vitamins, and herbal supplements.

Can the use of Triglynase 2 Tablet SR lead to Vitamin B12 deficiency?

Yes, the use of Triglynase 2 Tablet SR can cause vitamin B12 deficiency as it contains metformin in it. On long-term use, it interferes with absorption of vitamin B12 in the stomach.

Can the use of Triglynase 2 Tablet SR cause hypoglycemia?

Yes, the use of Triglynase 2 Tablet SR can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your meal, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always carry some sugary item like a candy or chocolate with you.

What are the instructions for the storage and disposal of Triglynase 2 Tablet SR?

Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

Therapeutic Class

ANTI DIABETIC

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

User feedback

Patients taking Triglynase 2 Tablet SR

Twice A Day

60%

Once A Day

40%

What are you using Triglynase Tablet SR for?

Type 2 diabetes mellitus

97%

Others

How much was the improvement?

Excellent

48%

Average

37%

Poor

15%

What were the side-effects while using Triglynase 2 Tablet SR?

No Side Effect

27%

Dizziness

20%

Hypoglycemia (low blood glucose level)

20%

Vomiting

Stomach pain

How do you take Triglynase Tablet SR?

With food

43%

Empty stomach

38%

With or without food

19%

Please rate Triglynase 2 Tablet SR on price

Average

45%

Expensive

36%

Not Expensive

18%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: USV Private Limited
Address: Arvind Vithal Gandhi Chowk, BSD Marg, Station Road, Govandi East, Mumbai - 400 088. , India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Triglynase 2 Tablet SR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

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Triglynase 2 Tablet SR

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Triglynase Tablet SR

Benefits of Triglynase Tablet SR

Side effects of Triglynase Tablet SR

How to use Triglynase Tablet SR

How Triglynase Tablet SR works

All substitutes for Triglynase 2 Tablet SR

TRIpride 2 Tablet SR

Triglimiprex 2 Tablet SR

Pioplus 2 Tablet SR

Geminor MP 2 Tablet SR

Triopil 2 Tablet SR

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Can I drink alcohol while taking Triglynase 2 Tablet SR?

What should I inform the doctor before taking Triglynase 2 Tablet SR?

Can the use of Triglynase 2 Tablet SR lead to Vitamin B12 deficiency?

Can the use of Triglynase 2 Tablet SR cause hypoglycemia?

What are the instructions for the storage and disposal of Triglynase 2 Tablet SR?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

User feedback

Patients taking Triglynase 2 Tablet SR

What are you using Triglynase Tablet SR for?

How much was the improvement?

What were the side-effects while using Triglynase 2 Tablet SR?

How do you take Triglynase Tablet SR?

Please rate Triglynase 2 Tablet SR on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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