


Zerogen 0.075mg Tablet
Product Summary :
Zerogen 0.075mg Tablet contains desogestrel, a progestogen-only contraceptive used to prevent pregnancy. It works mainly by preventing ovulation and thickening cervical mucus, reducing the chances of fertilization. It is usually taken at approximately the same time. Common side effects include headache, nausea, breast tenderness, and mood changes. It does not protect against sexually transmitted infections.Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 02 Nov 2026 | 01:02 AM (IST)
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General Information



Product introduction
Zerogen 0.075mg Tablet can be taken with or without food, but take it at the same time to get the most benefit. It should be taken as your doctor's advice. The doctor should guide the dose and how often you take it. Swallow the tablet whole with a glass of water. You should take this medicine for as long as it is prescribed for you. If you missed your dose and you are late by 12 hours in taking the missed dose, in that case, you must use a condom during intercourse for a period of 7 days.
The most common side effects of this medicine include headache, nausea, vomiting, weight gain, and acne. If these side effects persist or worsen, consult your doctor. They may suggest ways to minimize or prevent them.
Zerogen 0.075mg Tablet can often disrupt your menstrual cycle, so consult your doctor if this happens regularly. Before using this medication, inform your doctor if you have a history of diabetes, unexplained vaginal bleeding, or high blood pressure. Your doctor should also know about all other medicines you are taking, as many of these may make this medicine less effective or change the way it works. Generally, if you experience vomiting within 2 hours of dose intake, take another dose as soon as you feel better.
Uses of Zerogen Tablet
- Contraception : Used to prevent unwanted pregnancy in women of reproductive age. It works by preventing ovulation and thickening cervical mucus, making it difficult for sperm to reach and fertilise an egg.
Benefits of Zerogen Tablet
Zerogen 0.075mg Tablet is a progestin-only contraceptive that helps prevent pregnancy by thickening cervical mucus to block sperm and inhibiting ovulation in most cycles. It is suitable for women who cannot take estrogen-based contraceptives and is safe for use during breastfeeding. Additionally, it may help reduce menstrual pain and make periods lighter or stop altogether in some users.
Side effects of Zerogen Tablet
- Breast pain
- Weight gain
- Headache
- Nausea
- Mood changes
- Decreased libido
- Migraine
- Vomiting
- Abdominal pain
- Rash
- Red spots or bumps
How to use Zerogen Tablet
How Zerogen Tablet works
Dosage
Zerogen 0.075mg Tablet is usually taken at the same time each day, with or without food. Your doctor will advise when to start treatment and whether additional contraception is needed initially. Follow the prescribed schedule consistently, as missed or delayed tablets may reduce contraceptive protection.
All substitutes for Zerogen 0.075mg Tablet
Quick tips
- Take Zerogen 0.075mg Tablet at the same time every day without skipping any days, even between packs.
- If you are more than 12 hours late in taking a Zerogen 0.075mg Tablet, you will not be protected against pregnancy. Use other contraceptive methods, such as condoms, for the next two days.
- If you vomit within 2 hours of taking Zerogen 0.075mg Tablet, take another dose as soon as you feel well.
- It may stop your periods or make them lighter, irregular, or more frequent. Inform your doctor if this bothers you.
- Stop taking this medicine and inform your doctor immediately if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, severe headache, or vision changes. These could be the symptoms of a blood clot in a vein.
Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver
Use of Zerogen 0.075mg Tablet is not recommended in patients with severe liver disease and active liver disease.
Interaction with drugs
Letrozole (Oral Route)
Pomalidomide (Oral Route)
Tamoxifen (Oral Route)
Anastrozole (Oral Route)
Raloxifene (Oral Route)
Frequently asked questions
Fact Box
Chemical Class
Habit Forming
Therapeutic Class
Action Class
References
- Desogestrel/ethinyl estradiol [Prescribing Information]. Oss, The Netherlands: N.V. Organon; 2003. [Accessed 12 Feb. 2019] (online) Available from:
- Medecines Sans Frontiers: Medical Guidelines: Desogestrel. [Accessed 25 Jul. 2024] (online) Available from:
- Desogestrel [Package leaflet: Information for the User]. León, Spain: Laboratorios León Farma, S.A; 2015. [Accessed 03 Feb. 2025] (online) Available from:




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