Zapiz 0.25 Tablet

Prescription Required
SALT COMPOSITION
Storage
Store below 30°C
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Product introduction

Zapiz 0.25 Tablet is a prescription medicine used to treat epilepsy (seizures) and anxiety disorder. It helps to decrease the abnormal and excessive activity of the nerve cells and calms the brain.

Zapiz 0.25 Tablet may be taken with or without food. However, take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor as it has a high potential of habit-forming. If you have missed a dose, take it as soon as you remember it and finish the full course of treatment even if you feel better. You should not stop this medicine suddenly without talking to your doctor as it may increase the seizure frequency and can cause nausea, anxiety, flu-like symptoms, and muscle pain.

Some common side effects of this medicine include fatigue, depression and impaired coordination. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to inform your doctor if you develop any unusual changes in mood or depression as this medicine may cause suicidal thoughts.

Benefits of Zapiz Tablet

In Treatment of Anxiety disorder

Zapiz 0.25 Tablet stops your brain from releasing the chemicals that make you feel anxious so it can reduce the symptoms of excessive anxiety and worry. It can also reduce feelings of restlessness, tiredness, difficulty concentrating, feeling irritable and sleep problems that often come with Anxiety Disorder. It will therefore help you go about your daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping suddenly can cause serious problems.

In Treatment of Epilepsy/Seizures

Zapiz 0.25 Tablet slows down electrical signals in the brain which cause seizures (fits). It can also help reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. The medicine can allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). It can take a few weeks for this medicine to work (because the dose has to be increased slowly) and during this time you may still have seizures. Do not stop using this medicine even if you feel well, until your doctor advises you to. Missing doses may trigger a seizure.

Side effects of Zapiz Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zapiz

  • Depression
  • Dizziness
  • Drowsiness
  • Fatigue
  • Impaired coordination
  • Memory impairment

How to use Zapiz Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zapiz 0.25 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Zapiz Tablet works

Zapiz 0.25 Tablet is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Zapiz 0.25 Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Zapiz 0.25 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Zapiz 0.25 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Zapiz 0.25 Tablet may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Zapiz 0.25 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Zapiz 0.25 Tablet may be needed. Please consult your doctor.
Use of Zapiz 0.25 Tablet can cause excessive sleepiness in patients with end stage kidney disease.
Liver
CAUTION
Zapiz 0.25 Tablet should be used with caution in patients with liver disease. Dose adjustment of Zapiz 0.25 Tablet may be needed. Please consult your doctor.

What if you forget to take Zapiz Tablet?

If you miss a dose of Zapiz 0.25 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Avoid consuming alcohol as it may increase dizziness and drowsiness.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Inform your doctor if you experience worsen anxiety, depression angry, or violent behavior and mania while taking this medicine.
  • Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.

Fact Box

Chemical Class
Benzodiazepines Derivative
Habit Forming
Yes
Therapeutic Class
NEURO CNS
Action Class
Benzodiazepines

Interaction with drugs

Taking Zapiz with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Abamune, A-Bec
Serious
Brand(s): Adesera, Adheb, Adfovir
Serious
Brand(s): Stozen, Sulpigold, Amisulide
Serious
Brand(s): Triptam
Serious

Patient concerns

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Suffering from anxiety disorder with mild depressi Medicines are : zosert 50 - 1.5 tab per day, zapiz : 0.5 a day. Have to take BP meds and for dyslipidemia. How to get rid of from zapiz because there is a dependence on that ? Prescribe please.
Dr. Jyoti Kapoor Madan
Psychiatry
Reduce zapiz by 0.25 mg for a few weeks and then further by half. If you feel anxious, sertraline dose may need to be adjusted.
using zapiz for last 2 year but now sleeping is very less
Dr. Jyoti Kapoor Madan
Psychiatry
Sleep problems are often caused by underlying physical and/ or psychological cause. This requires examination of the patient so that proper treatment can be initiated. Often stress/ anxiety/ depression or mood disorder needs to be dealt with and sleeping pills are not adequate treatment. Please go through the link below - http://drjyotikapoor.com/2015/01/26/sleep-disorders/
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User feedback


FAQs

Q. Is Zapiz 0.25 Tablet a sleeping pill?

Zapiz 0.25 Tablet belongs to a class of medicines called benzodiazepines and is used to treat anxiety, stop seizures (fits) or relax tense muscles. This can also help relieve difficulty sleeping (insomnia), and is usually prescribed for a short period of time, if used to treat sleeping problems. You should take it in the dose and duration advised by the doctor.

Q. Does Zapiz 0.25 Tablet cause sleepiness? If yes, then should I stop driving while taking Zapiz 0.25 Tablet?

Yes, Zapiz 0.25 Tablet causes drowsiness very commonly. It also causes forgetfulness and affects muscular function which may adversely affect your ability to drive. Sometimes, drowsiness persists even on the following day. So, in case Zapiz 0.25 Tablet makes you sleepy and affects your alertness, you should avoid driving.

Q. For how long should I take Zapiz 0.25 Tablet?

The duration of treatment with Zapiz 0.25 Tablet is mainly as short as possible. Your doctor will evaluate you after 4 weeks of treatment in order to assess the need for continuation of treatment, especially if you do not have any symptoms. Before taking you off this medicine, your doctor may gradually decrease your dose to prevent any withdrawal side effects. Follow your doctor’s instructions carefully to get the most benefit.

Q. Is it safe to take Zapiz 0.25 Tablet and alcohol together?

No, it is not at all recommended to take alcohol with Zapiz 0.25 Tablet since it can cause breathing problems, sleepiness and heart problems. Taking Zapiz 0.25 Tablet with alcohol may make you sleepy and your breathing may become so shallow that you may not wake up. This may even lead to death.

Q. Is Zapiz 0.25 Tablet addictive?

People taking Zapiz 0.25 Tablet in high doses or for a long term may become addicted to it. Also, people with a history of alcoholism and drug abuse are more likely to become addicted to Zapiz 0.25 Tablet. Therefore, Zapiz 0.25 Tablet should be taken for the shortest possible time and in the lowest effective dose.

Q. Can I stop taking Zapiz 0.25 Tablet if I start feeling better?

No, do not stop taking Zapiz 0.25 Tablet suddenly as you may experience withdrawal effects like depression, nervousness, difficulty in sleeping, irritability, sweating, upset stomach or diarrhea. Stopping it suddenly may even bring back the symptoms and make them harder to treat. You may also experience mood changes, anxiety, restlessness and changes in sleep patterns. These effects may occur even after taking low doses for a short period of time.

Q. Are there any foods we need to avoid while taking Zapiz 0.25 Tablet?

Yes, you should avoid taking foods containing caffeine such as tea, coffee, chocolates etc., while taking Zapiz 0.25 Tablet. This is because caffeine stimulates your brain and Zapiz 0.25 Tablet calms the brain. So, taking too much caffeine can affect the calming ability of this medicine and worsen your condition. Also, you should avoid taking alcohol while on treatment with Zapiz 0.25 Tablet. Alcohol can cause excessive sleepiness and make you more drowsy and inattentive. Talk to your doctor if you have any other doubts regarding your diet while taking Zapiz 0.25 Tablet.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Stahl SM, editor. Clonazepam. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 137-41.
  2. McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 598-99.
  3. Porters RJ, Meldrum BS. Antiseizure Drugs. Sedative-Hypnotic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 415.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 301-303.
  5. Clonazepam. Roche; [revised Apr. 2009]. [Accessed 22 Mar. 2019] (online) Available from:External Link
  6. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Clonazepam. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:External Link
  7. Clonazepam. Boucherville, Québec: Sandoz Canada Inc.; 2018. [Accessed 22 Mar. 2019] (online) Available from:External Link
  8. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Country of origin: India

NOT FOR SALE
We do not facilitate sale of this product at present

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