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Adefovir is used for treating symptoms of chronic inflammation of the liver (hepatitis) caused by hepatitis B virus (chronic hepatitis B).

How it works

Adefovir is a nucleotide analogue. It works by slowing the growth of the hepatitis B virus.

Common side effects

Cough, Diarrhoea, Flatulence, Headache, Indigestion, Rash, Itching, Running nose, Sore throat, Vomiting, Weakness, Fatigue


Expert advice

  • Adefovir does not prevent the spread of hepatitis B virus to others. Take the required precautions to prevent transmission.
  • Do not stop taking adefovir, unless advised, as doing so may worsen your condition.
  • Adefovir may cause kidney damage. Tell your doctor if you have or had kidney disease, high blood pressure, or diabetes.
  • If you have untreated HIV/AIDS, taking adefovir can cause HIV infection to become resistant to the standard HIV/AIDS medications.
  • You may need to undergo blood tests every three months to ensure that adefovir is keeping your chronic hepatitis B infection under control.
  • You may need to monitor your liver function for several months after you stop using adefovir.
  • Adefovir can cause serious or life-threatening damage to the liver and a condition called lactic acidosis (a build-up of acid in the blood causing muscle pain or weakness, trouble breathing, stomach pain, nausea with vomiting, fast or irregular heartbeats, dizziness or tiredness). Stop taking this medicine immediately if you experience any such reaction.
  • Women should use an effective method of contraception to avoid becoming pregnant while on adefovir therapy.

Frequently asked questions


Q. What is adefovir dipovoxil?
Adefovir dipovoxil is one of the salt form of adefovir, and is used for the treatment of chronic hepatitis B.
Q. How does adefovir work?
Adefovir works by slowing the growth of the hepatitis B virus.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)