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Zafimove 50mg Tablet

Safinamide (50mg)
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Zafimove 50mg Tablet is a medicine used to treat Parkinson's disease. It helps to provide better control of body movements and prevents excessive shaking and stiffness. It increases the concentration of a chemical in the brain called dopamine that plays a major role in movement control.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 28 Aug 2026 | 01:04 AM (IST)
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Free Return

within 7 days

Expiry after

Jul, 2027

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General Information

The content is shown in English
Zafimove 50mg Tablet image
Zafimove 50mg Tablet image
Zafimove 50mg Tablet image
Zafimove 50mg Tablet image
Zafimove 50mg Tablet image
Zafimove 50mg Tablet image

Product introduction

Zafimove 50mg Tablet can be taken alone or in combination with other medicines. It may be taken with or without food, but preferably take it in the morning. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor.

If you have missed a dose, take it as soon as you remember it. You should never skip any doses and try to finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it can result in confusion, stiff muscles and a high fever.

Some common side effects of this medicine include involuntary muscle movement, fall, nausea, and insomnia (difficulty sleeping). It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is suggested to reduce/avoid a high-protein diet (eg.meat, poultry, and dairy products) while taking Zafimove 50mg Tablet as it can cause unsafe high blood pressure.

You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by, this medicine. Pregnant and breastfeeding mothers should consult their doctor before using it.

Uses of Zafimove Tablet

Benefits of Zafimove Tablet

Parkinson's disease
Parkinson's disease is a progressive brain disorder that affects movement, causing symptoms like tremors, stiffness, slowed movements, and balance problems. Zafimove 50mg Tablet helps improve movement control and reduces symptoms such as stiffness and slowness, making daily activities easier and improving overall quality of life for people living with the condition.

Side effects of Zafimove Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zafimove
  • Involuntary muscle movement
  • Fall
  • Nausea
  • Insomnia (difficulty in sleeping)

How to use Zafimove Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zafimove 50mg Tablet may be taken with or without food.

How Zafimove Tablet works

Zafimove 50mg Tablet works by increasing the amount of dopamine, a chemical messenger that is needed to control movement in the brain.

All substitutes for Zafimove 50mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Zafimove 50mg Tablet can be taken with or without food or as directed by your doctor.
  • Reduce/avoid a high-protein diet (eg.meat, poultry, and dairy products) while you are taking the medicine as it may cause an unsafe rise in your blood pressure.
  • Use caution while driving or doing anything that requires concentration as Zafimove 50mg Tablet can make you very sleepy.
  • Talk to your doctor in case you develop hallucinations or other changes in your behavior.
  • Do not stop taking Zafimove 50mg Tablet without first talking to your doctor. Sudden stopping may cause confusion, stiff muscles and a high fever.
  • Zafimove 50mg Tablet can be taken with or without food or as directed by your doctor.
  • Reduce/avoid a high-protein diet (eg.meat, poultry, and dairy products) while you are taking the medicine as it may cause an unsafe rise in your blood pressure.
  • Use caution while driving or doing anything that requires concentration as Zafimove 50mg Tablet can make you very sleepy.
  • Talk to your doctor in case you develop hallucinations or other changes in your behavior.
  • Do not stop taking Zafimove 50mg Tablet without first talking to your doctor. Sudden stopping may cause confusion, stiff muscles and a high fever.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Zafimove 50mg Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Zafimove 50mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CAUTION
Zafimove 50mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

UNSAFE
Zafimove 50mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Zafimove 50mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Zafimove 50mg Tablet in patients with liver disease.
Zafimove 50mg Tablet should not be used in severe liver impairment.

Interaction with drugs

Taking Zafimove with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Bupropion (Oral Route)

Do not consume Safinamide with Bupropion. If Safinamide is essential, ensure a gap of at least 24 hours after discontinuing Bupropion. Please consult your doctor.
Life-threatening

Linezolid (Oral Route)

Do not consume Safinamide with Linezolid. If Safinamide is essential, ensure a gap of At least 2 weeks between taking Safinamide and Linezolid. Please consult your doctor.
Life-threatening

Linezolid (Injection Route)

Do not consume Safinamide with Linezolid. If Safinamide is essential, ensure a gap of At least 2 weeks between taking Safinamide and Linezolid. Please consult your doctor.
Life-threatening

Linezolid (Oral Route)

Do not consume Safinamide with Linezolid. If Safinamide is essential, ensure a gap of At least 2 weeks between taking Safinamide and Linezolid. Please consult your doctor.
Life-threatening

Linezolid (Oral Route)

Do not consume Safinamide with Linezolid. If Safinamide is essential, ensure a gap of At least 2 weeks between taking Safinamide and Linezolid. Please consult your doctor.

Frequently asked questions

Zafimove 50mg Tablet is used to treat Parkinson's disease. Your doctor can usually prescribe Zafimove 50mg Tablet with levodopa/carbidopa to provide better control of body movements and prevent excessive shaking and stiffness, helping smooth out motor symptoms when levodopa wears off between doses.
During Zafimove 50mg Tablet treatment, it is advised to avoid foods extremely high in tyramine (for example, very aged cheeses or heavily fermented/cured items) because they can trigger dangerous blood pressure spikes; never exceed the recommended dose.
Yes, Zafimove 50mg Tablet can cause new or worsening high blood pressure. Blood pressure should be checked regularly, and extra caution is needed if using decongestants or cold remedies that also raise blood pressure.
Get help right away for symptoms of serious side effects of Zafimove 50mg Tablet such as serotonin syndrome (confusion, agitation, fever, stiff or twitching muscles, fast heartbeat, high/low blood pressure), severe hypertension (sudden, severe headache, chest pain), severe allergic reactions (swelling of tongue/mouth, trouble breathing), sudden sleep episodes, or new/worsening hallucinations.
Yes, dyskinesia can start or get worse during Zafimove 50mg Tablet treatment. Your doctor may lower the levodopa dose or adjust other Parkinson’s medicines, which may be needed if movements become troublesome.
People taking Zafimove 50mg Tablet can suddenly fall asleep during normal activities, sometimes without warning. If daytime sleepiness or sudden sleep occurs, stop risky activities and contact the doctor promptly.
Yes, hallucinations or psychotic‑like symptoms can occur during Zafimove 50mg Tablet treatment. Also, some people develop strong, unusual urges (gambling, spending, sexual urges, binge eating). Report these behaviors so the dose or therapy can be adjusted by your doctor.

Fact Box

Chemical Class

Alpha amino acid amides

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Monoamine Oxidase-B (MAO-B) Inhibitors
Related ayurvedic ingredients
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Torrent Pharmaceuticals Ltd
Address: Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Zafimove 50mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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