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Xyloris 0.05% Nasal Spray

Xylometazoline (0.05% w/v)

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Xyloris 0.05% Nasal Spray is a medicine that helps clear and soothes the blocked nose, thereby relieving nasal congestion due to common cold, hay fever, or other respiratory allergies in children.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 10 Oct 2026 | 01:01 AM (IST)

₹35.4 MRP ₹40.6413% off

(Inclusive of applicable taxes)

Gurgaon

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General Information

Contains

Xylometazoline (0.05% w/v)

Marketer

Eris Lifesciences Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Xyloris 0.05% Nasal Spray is meant to be used externally by nasal route only. Put it into each nostril strictly as prescribed by your child’s doctor. Try not to touch the tip of the medicine container while putting it in your child’s nose. If this happens, rinse the tip with hot water and dry with a clean tissue before recapping the medicine container. Close one nostril while applying the medicine into the other, and then ask your child to sniff hard to make sure it reaches deep into the nose. Once done, repeat for the other nostril.

Xyloris 0.05% Nasal Spray provides quick relief, approximately within 2 minutes that lasts for several hours (up to 10 hours). It is recommended to make the last application shortly before your child retires to bed. It renders only temporary relief, so do not use it more often or for longer than recommended. Using it for a longer duration may cause side effects. On the other hand, stopping the medicine abruptly can make the congestion come back with severity and can worsen your child’s condition.

This medicine may have some minor and temporary side effects such as irritation in the nose, nasal dryness, feeling sick (nausea), headache, or application site burning. These episodes should start receding after a few doses. However, if these side effects persist or become bothersome for your child, report to the doctor without any delay. Follow all the instructions as suggested by your child’s doctor and as mentioned over the medicine label.

Uses of Xyloris Nasal Spray

Nasal congestion (blocked nose)

Benefits of Xyloris Nasal Spray

Nasal congestion (blocked nose)
Nasal congestion occurs when the blood vessels in the nose swell and produce excess mucus, making it hard to breathe. Xyloris 0.05% Nasal Spray helps shrink the swollen blood vessels inside the nose, reducing blockage and clearing the nasal passages. This provides quick relief from a blocked or stuffy nose, making breathing easier and more comfortable.

Side effects of Xyloris Nasal Spray

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Xyloris

Nausea
Headache
Application site burning
Application site irritation

How to use Xyloris Nasal Spray

Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Insert the bottle tip into one nostril and close the other nostril. Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose. As you spray, breath gently and keep the head upright. Repeat the same process for the other nostrils.

How Xyloris Nasal Spray works

Xyloris 0.05% Nasal Spray is a nasal decongestant. It helps in opening up the nasal passages by reducing excessive nasal secretions and also reducing the swelling in the blood vessels in the inner surface of the nose. This provides temporary relief from congestion or stuffiness in the nose.

All substitutes for Xyloris 0.05% Nasal Spray

For information purposes only. Consult a doctor before taking any medicine.

Orinase Paediatric Nasal Spray

by Entod Pharmaceuticals Ltd

₹43.13/nasal spray

6% costlier

Quick tips

Do check the medicine’s ‘expiry’ date before using it.
Do not give more than the recommended dose as it can lead to side effects.
Do not use it more than 3 times a day.
Prolonged use and abrupt stoppage of Xyloris 0.05% Nasal Spray can lead to complications. Follow the doctor’s prescription carefully.
One container of Xyloris 0.05% Nasal Spray should only be used only by one person. This is to avoid spreading infection from one person to another. Do not share the same medicine with others.
Encourage your child to inhale the steam as it may help relieve symptoms.

Safety advice

Alcohol

No interaction found/established

Pregnancy

CONSULT YOUR DOCTOR

The safety of Xyloris 0.05% Nasal Spray during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Xyloris 0.05% Nasal Spray during breastfeeding is not available. Please consult your doctor.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

Interaction with drugs

Taking Xyloris with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Furazolidone (Oral Route)

Do not consume Furazolidone with Xylometazoline. If essential, consult your doctor.

Life-threatening

Sevoflurane (Oral Route)

Do not consume Sevoflurane with Xylometazoline.

Life-threatening

Sevoflurane (Inhalation Route)

Do not consume Sevoflurane with Xylometazoline.

Life-threatening

Tranylcypromine (Oral Route)

Do not consume Tranylcypromine with Xylometazoline. If Tranylcypromine is essential, ensure a gap of At least 2 weeks after discontinuing Xylometazoline. Please consult your doctor.

Moderate

Selegiline (Oral Route)

Do not consume Selegiline with Xylometazoline. If concurrent use is essential, your doctor may monitor your blood pressure frequently.

Frequently asked questions

Can I give Xyloris 0.05% Nasal Spray to my child continuously for more than 2 weeks if he has on and off nasal congestion?

Do not give Xyloris 0.05% Nasal Spray to your child for more than 10 consecutive days as it may lead to complications such as "atrophic rhinitis". Also, make sure not to stop the medicine suddenly as doing so can cause ‘‘rebound congestion'’ in your child. Therefore, it is advised to follow the prescribed dosing schedule.

What if I give too much of Xyloris 0.05% Nasal Spray to my child by mistake?

An overdose of Xyloris 0.05% Nasal Spray can cause severe dizziness, perspiration, severely lowered body temperature, headache, bradycardia (low heart rate), hypertension, respiratory depression, coma, and convulsions. It may even cause high blood pressure followed by a fall in blood pressure. Moreover, children are more sensitive to toxicity than adults, so it is advised that you reach out to your child’s doctor immediately if this happens.

How to use Xyloris 0.05% Nasal Spray in my child?

Before using Xyloris 0.05% Nasal Spray, ask your child to clear the nose by blowing gently. Ask your child to lay down and lookup. Tilt your child’s head back as far as comfortable, or if lying on a bed, keep the head over the side. Open the cap of the medicine container and without touching the nozzle to the nose, apply the medicine into each nostril. Ask your child to keep the head tilted back for a short time as that will allow the drops to spread throughout the nose. Replace the cap right after use. If the drop completely misses the nose, administer the drop again. If any part of the drop gets into the nose, do not administer the drop again. Repeat for the other nostril. Clean and dry the nozzle before replacing the cap right after use. To avoid the possible spread of infection, the bottle should only be used by one person.

When should I call my child’s doctor right away?

Call your child’s doctor if your child is bothered by signs such as insomnia, dizziness, tremor, irregular heartbeat, or elevated blood pressure after the use of Xyloris 0.05% Nasal Spray.

Can other medicines be given at the same time as Xyloris 0.05% Nasal Spray?

Xyloris 0.05% Nasal Spray can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Xyloris 0.05% Nasal Spray. Also, check with your child’s doctor before giving any medicine to your child.

In what position should I make my child sleep when he is having a stuffy nose?

To sleep with a stuffy nose, make your child lie on his back with a pillow to help the mucus drain out. Abstain your child from sleeping on the side position since it may increase the congestion in one or both nostrils.

Fact Box

Chemical Class

Phenylpropanes

Habit Forming

Therapeutic Class

RESPIRATORY

Action Class

Sympathomimetics- Alpha-1 (Nasal)

References

Biaggioni I, Robertson D. Adrenoreceptor Agonists & Sympathomimetic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 140.
Xylometazoline hydrochloride [EMC SmPC]. Brentford, UK: GlaxoSmithKline Consumer Healthcare; 2020. [Accessed 17 May 2021] (online) Available from:
Pediatric Oncall: Child Health Center. Xylometazoline. [Accessed 17 May 2021] (online) Available from:
Otrivin [Product Information]. [Accessed 17 May 2021] (online) Available from:
Otrivin Paediatric. Nabha, Punjab: GlaxoSmithKline Consumer Private Limited; 2017. [Accessed 17 May 2021] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Eris Lifesciences Ltd
Address: 8th Floor, Commerce House IV, Prahladnagar, Ahmedabad – 380015 Gujarat, India \ 7th Floor, Commerce House-4, Prahlad Nagar, Ahmedabad, Gujarat - 380015

Vendor Details

Country of origin: India

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Respiratory

Topical Nasal Preparations Non Steroidal

Xyloris 0.05% Nasal Spray

Xyloris 0.05% Nasal Spray

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Xyloris Nasal Spray

Benefits of Xyloris Nasal Spray

Side effects of Xyloris Nasal Spray

How to use Xyloris Nasal Spray

How Xyloris Nasal Spray works

All substitutes for Xyloris 0.05% Nasal Spray

Orinase Paediatric Nasal Spray

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Furazolidone (Oral Route)

Sevoflurane (Oral Route)

Sevoflurane (Inhalation Route)

Tranylcypromine (Oral Route)

Selegiline (Oral Route)

Frequently asked questions

Can I give Xyloris 0.05% Nasal Spray to my child continuously for more than 2 weeks if he has on and off nasal congestion?

What if I give too much of Xyloris 0.05% Nasal Spray to my child by mistake?

How to use Xyloris 0.05% Nasal Spray in my child?

When should I call my child’s doctor right away?

Can other medicines be given at the same time as Xyloris 0.05% Nasal Spray?

In what position should I make my child sleep when he is having a stuffy nose?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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