Xolimus 10 Tablet is used for the prevention of organ rejection in transplant patients. It regulates the body’s immune response, so the body can accept the new organ. It is also used in combination with other medicines to treat cancers of breast, pancreas, lungs, and kidney.
Xolimus 10 Tablet must be taken in a dose and duration as per the prescription. It can be taken with or without food but make sure to take it at about the same time every day. An overdose of this medicine may have serious side effects on the body.
The common side effects of this medicine include infection, fever, cough, fatigue, diarrhea, and upper respiratory infection. If any of the side effects persist or bother you, consult the doctor immediately. Inform the doctor immediately if you experience any allergic reactions (rash, shortness of breath, coughing, swelling, etc.). Always seek medical advice if you have increased thirst or increased frequency of urination, suffer from shortness of breath, cough or fever, or need to receive any vaccination after taking this medication.
Before taking this medicine, it is important to consult your doctor if you have any ongoing medication for any underlying disease. Pregnant and breastfeeding women must inform the doctor prior to the initiation of this treatment. During the treatment, your doctor may advise you for some laboratory tests to know the effects of the medicine in the body. It may affect male or female fertility, so consult the doctor if you are planning to have a child.
In Prevention of organ rejection in transplant patients
Xolimus 10 Tablet is used with other medications to prevent organ transplant rejection. Rejection usually happens due to attack by the immune system of the person receiving the transplanted organ on the transplant itself, in people who are receiving any organ transplants, like kidney, liver, heart etc. This medicine reduces the activity of a person's own immune system and prevents any such rejection.
Side effects of Xolimus Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Xolimus
Infection
Fever
Cough
Fatigue
Diarrhea
Upper respiratory tract infection
How to use Xolimus Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xolimus 10 Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Xolimus Tablet works
Xolimus 10 Tablet suppresses the activity of body's immune system and prevents rejection of the transplanted organ.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Xolimus 10 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Xolimus 10 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Xolimus 10 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Xolimus 10 Tablet may cause side effects which could affect your ability to drive. As fatigue is a common side effect with Xolimus 10 Tablet and this may affect your ability to drive
Kidney
SAFE IF PRESCRIBED
Xolimus 10 Tablet is safe to use in patients with kidney disease. No dose adjustment of Xolimus 10 Tablet is recommended.
Liver
CAUTION
Xolimus 10 Tablet should be used with caution in patients with liver disease. Dose adjustment of Xolimus 10 Tablet may be needed. Please consult your doctor. Use of Xolimus 10 Tablet is not recommended in patients with severe liver disease.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Xolimus 10 Tablet is given for the treatment of certain cancers and to prevent organ transplant rejection.
Xolimus 10 Tablet may affect male or female fertility; consult your doctor if you are planning to have a child.
Inform your doctor straight away if you think you are getting a sore throat or if you have a high temperature. This is because Xolimus 10 Tablet increases your risk of getting an infection.
While you are taking Xolimus 10 Tablet do not take any vaccinations without talking to your doctor first.
If you are having an operation or dental treatment, always tell the person carrying out the treatment that you are taking Xolimus 10 Tablet.
Do not drink grapefruit juice while you are taking this medicine. This is because a chemical in grapefruit juice can interfere with the action of Xolimus 10 Tablet.
Fact Box
Chemical Class
Macrolide Lactams
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Patient concerns
Difficulty in excretory, and rejection of stool.
Dr. Aanchal Maheshwari
Ayurveda
take triphala churan 1 spoon at night wioth abhyarishtam 20 ml mixed with water
Dear respected sir/madam, my uncle is suffering from alcoholic liver cirrhosis and ascites due to prolonng drinking. Water is accumulated around the belly. Less ddesire to eat anything. Doctor is saying for liver transplant. Could please suggest the best treatment available in allopathy to treat this problem. Thank you very very much.
Wash acne-prone areas only twice a day. Washing removes excess oil and dead skin cells. But too much washing can irritate the skin. Wash affected areas with a gentle cleanser and use oil-free, water-based skin care products. Use non- oily makeup. Choose oil-free cosmetics that won't clog pores. Remove makeup before going to bed. Going to sleep with cosmetics on your skin can clog your pores. Avoid touching or picking at the problem areas. Doing so can trigger more acne. Always use a clean towel or cloth to wipe your face. Always keep your hands clean and wash them regularly so that you may not touch your skin with dirty hands.
If eye ratina is fully damaged then eye can be transplant
Dr. Vishal Maniar
Ophthalmology
Complete eye transplant yet not done not possible yet Only corneal transplant can be doneIf retina is fully damaged corneal transplant is not advisable as the visual prognosis is guarded
Q. Is any monitoring required while taking Xolimus 10 Tablet?
Regular monitoring is required while you are on Xolimus 10 Tablet. The doctor will advise blood tests to see the counts of red blood cells, white blood cells, and platelets since the counts may decrease during treatment with Xolimus 10 Tablet. Also, blood tests will be required to check your kidney function, liver function, blood glucose levels, and cholesterol levels.
Q. What should I avoid while taking Xolimus 10 Tablet?
You should avoid grapefruit or grapefruit juice while taking Xolimus 10 Tablet. This is because taking them together may increase the levels of Xolimus 10 Tablet in your blood to harmful levels. Avoid the use of live vaccinations and any possible contact with individuals who have received live vaccinations.
Q. What is the most important information I need to know about Xolimus 10 Tablet?
Xolimus 10 Tablet can cause serious side effects which include severe allergic reactions, angioedema, and kidney failure which can be severe and can lead to death. It is possible that you may develop an infection or problems related to lung such as breathing problems.
Q. Is Xolimus 10 Tablet a chemotherapy?
Xolimus 10 Tablet is an anticancer medicine. It belongs to kinase inhibitor class of medicines. It works by reducing the blood supply to the tumor, which slows down the growth and spread of cancer cells.
Q. How is Xolimus 10 Tablet administered?
Usually, Xolimus 10 Tablet is taken once or twice daily. The medicine should always either be taken with food or always be taken without food. Xolimus 10 Tablet should be swallowed whole with water and should not be crushed or chewed.
Q. How long can you take Xolimus 10 Tablet?
There is no definite duration of treatment with Xolimus 10 Tablet. Xolimus 10 Tablet is continued till clinical benefit is seen or unacceptable toxicity or side effects occur.
Q. How will I know that Xolimus 10 Tablet is shrinking my brain tumor?
The effect of Xolimus 10 Tablet in shrinking the size of tumor can only be checked by getting regular brain scans. It should be done as advised by your doctor and your treatment plan.
Q. Is Xolimus 10 Tablet cytotoxic?
Yes, Xolimus 10 Tablet is cytotoxic against human cancer cells of breast, stomach, prostate, and kidneys (renal cell carcinoma).
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References
Krensky AM, Bennett WM, Vincenti F. Immunosuppressants, Tolerogens, and Immunostimulants. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1013.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 526.
Everolimus. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2009 [revised Apr. 2018]. [Accessed 06 Apr. 2019] (online) Available from:
Everolimus. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2011 [revised 12 Jul 2018]. [Accessed 22 Jan. 2019] (online) Available from:
CiplaMed. Tacrolimus [Prescribing Information]. [Last Updated: 17 May 2021]. [Accessed 20 Feb. 2024] (online) Available from:
Everolimus [Prescribing Information]. Berkeley Heights: Hikma Pharmaceuticals USA Inc.; 2023. [Accessed 20 Feb. 2024] (online) Available from:
Marketer details
Name: Cadila Pharmaceuticals Ltd
Address: Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, INDIA.
Country of origin: India Expires on or after: December, 2024
A licensed vendor partner from your nearest location will deliver Xolimus 10 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID:[email protected] Phone Number: 0124-4166666 Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India