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Everolimus

Written By Dr. Anuj SainiReviewed By Dr. Rajeev Sharma
Last updated 25 Nov 2025 | 09:34 AM (UTC)

Everolimus Uses

How Everolimus works

Everolimus suppresses the activity of body's immune system and prevents rejection of the transplanted organ.

Common side effects of Everolimus

Decreased appetite, Increased glucose level in blood, Pneumonitis, Hypercholesterolemia (high cholesterol), Increased aspartate aminotransferase, Decreased white blood cell count (lymphocytes), Lymphopenia, Increased alanine aminotransferase, Increased triglyceride level in blood, Joint pain, Pleural effusion, Pulmonary edema, Rash, Diarrhea, Infection, Breathlessness, Stomatitis (Inflammation of the mouth), Fatigue, Anemia (low number of red blood cells), Low blood platelets, Decreased potassium level in blood, Weight loss, Taste change
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Medicine brands for Everolimus

Evermil
Glenmark Pharmaceuticals Ltd
â‚ą6187 to â‚ą7450
2 variant(s)
Evermil
Rolimus
Cipla Ltd
â‚ą8070 to â‚ą11434
2 variant(s)
Rolimus
RAPact
Natco Pharma Ltd
â‚ą15000 to â‚ą25000
2 variant(s)
RAPact
Volantis
Dr Reddy's Laboratories Ltd
â‚ą6438 to â‚ą9837
2 variant(s)
Volantis
everTOR
Biocon
â‚ą9644 to â‚ą14690
2 variant(s)
everTOR
Everotas
Intas Pharmaceuticals Ltd
â‚ą430 to â‚ą30000
4 variant(s)
Everotas
Advacan
Eris Lifesciences Ltd
â‚ą642 to â‚ą1204
2 variant(s)
Advacan
Evergraf
Panacea Biotec Pharma Ltd
â‚ą700 to â‚ą1570
2 variant(s)
Evergraf
Afinitor
Novartis India Ltd
â‚ą19882 to â‚ą60146
2 variant(s)
Afinitor
Boletraaz
Alkem Laboratories Ltd
â‚ą19800 to â‚ą29700
2 variant(s)
Boletraaz

Expert advice for Everolimus

  • Do not start everolimus and consult your doctor if you have liver problems, diabetes, high blood cholesterol, had a recent surgery or have unhealed wound after surgery, have infection, previously had hepatitis, are pregnant or breast-feeding or have intolerance to some sugars.
  • Seek medical advice if you have increased thirst or increased frequency of urination, if you get any infection, suffer from shortness of breath, cough or fever, need to receive any vaccination after taking everolimus.
  • Everolimus may affect male or female fertility; consult your doctor if you are planning to have a child.
  • Do not drive or operate machinery while taking everolimus as it may cause fatigue.

Frequently asked questions for Everolimus

Everolimus is an anticancer medicine. It belongs to kinase inhibitor class of medicines. It works by reducing the blood supply to the tumor, which slows down the growth and spread of cancer cells.
Usually, Everolimus is taken once or twice daily. The medicine should always either be taken with food or always be taken without food. Everolimus should be swallowed whole with water and should not be crushed or chewed.
There is no definite duration of treatment with Everolimus. Everolimus is continued till clinical benefit is seen or unacceptable toxicity or side effects occur.
Regular monitoring is required while you are on Everolimus. The doctor will advise blood tests to see the counts of red blood cells, white blood cells, and platelets since the counts may decrease during treatment with Everolimus. Also, blood tests will be required to check your kidney function, liver function, blood glucose levels, and cholesterol levels.
The effect of Everolimus in shrinking the size of tumor can only be checked by getting regular brain scans. It should be done as advised by your doctor and your treatment plan.
You should avoid grapefruit or grapefruit juice while taking Everolimus. This is because taking them together may increase the levels of Everolimus in your blood to harmful levels. Avoid the use of live vaccinations and any possible contact with individuals who have received live vaccinations.
Everolimus can cause serious side effects which include severe allergic reactions, angioedema, and kidney failure which can be severe and can lead to death. It is possible that you may develop an infection or problems related to lung such as breathing problems.
Yes, Everolimus is cytotoxic against human cancer cells of breast, stomach, prostate, and kidneys (renal cell carcinoma).