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Valsazem 40 Tablet

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 19 Jan 2026 | 02:24 PM (IST)
Valsazem 40 Tablet is used to treat high blood pressure and heart failure. Lowering blood pressure helps to prevent future heart attacks and stroke. This medicine is also effective in preserving kidney function in patients with diabetes.
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General Information

The content is shown in English
Valsazem 40 Tablet image
Valsazem 40 Tablet image
Valsazem 40 Tablet image

Product introduction

Valsazem 40 Tablet can be prescribed either alone or in combination with other medicines. It may be taken with or without food during the day or at night. However, try to take it at the same time each day to get the most benefit. It is important to continue taking it regularly even if you feel well or if your blood pressure is controlled. Most people with high blood pressure do not feel ill, but if you stop taking this medicine, your condition could get worse. This is a widely used medicine and is considered safe for long-term use.

Making some changes in your lifestyle will also help lower your blood pressure. These may include regular exercise, losing weight, smoking cessation, reducing alcohol intake, and reducing the amount of salt in your diet as advised by your doctor. This medicine is tolerated well by most patients and has few side effects. Dizziness, particularly after the first dose, is known to occur in some people. This may be associated with low blood pressure, orthostatic hypotension, and rash. Let your doctor know if these side effects bother you or do not go away. No weight gain has been seen with the regular use of this medicine.

Before taking this medicine, let your doctor know if you have any kidney or liver problems. Pregnant or breastfeeding mothers should also consult their doctor before taking it. Your doctor may check your kidney function, blood pressure and potassium levels in your blood at regular intervals while you are taking this medicine.

Uses of Valsazem Tablet

Benefits of Valsazem Tablet

Hypertension (high blood pressure)
Hypertension (high blood pressure) is a condition where the force of the blood against artery walls is consistently too high, increasing the risk of heart disease, stroke, and kidney problems. Valsazem 40 Tablet helps manage blood pressure, reducing the strain on the heart and arteries. This lowers the chances of complications and supports long-term cardiovascular health.
Heart Failure
Heart failure occurs when the heart cannot pump blood efficiently, leading to fatigue, shortness of breath, and fluid buildup. Valsazem 40 Tablet helps improve heart function in such cases by easing the workload on the heart, improving circulation, and enhancing the overall quality of life for patients.
Prevention of heart attack and stroke
Preventing heart attack and stroke is crucial for those at high cardiovascular risk. Valsazem 40 Tablet plays a preventive role by keeping blood pressure under control and protecting blood vessels, which significantly reduces the likelihood of major cardiovascular events like heart attacks and strokes.

Side effects of Valsazem Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Valsazem
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Dizziness
  • Decreased blood pressure
  • Rash
  • Increased creatinine level in blood

How to use Valsazem Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Valsazem 40 Tablet may be taken with or without food.

How Valsazem Tablet works

Valsazem 40 Tablet is an angiotensin receptor blocker (ARB). It relaxes the blood vessel by blocking the action of a chemical that usually makes blood vessels tighter. This lowers the blood pressure, allowing the blood to flow more smoothly to different organs and the heart to pump more efficiently.

Quick tips

  • It can make you feel dizzy for the first few days. Rise slowly if you have been sitting or lying down for a long time.
  • Your doctor may get regular tests done to monitor the level of urea, creatinine, and potassium in your blood.
  • Avoid taking anti-inflammatory medicines such as ibuprofen along with this medicine without consulting your doctor.
  • Do not take Valsazem 40 Tablet if you are pregnant or breastfeeding.
  • Do not stop taking it suddenly without talking to your doctor.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Valsazem 40 Tablet. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Valsazem 40 Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

UNSAFE
Valsazem 40 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

CAUTION
Valsazem 40 Tablet may cause dizziness or weakness due to changes in blood pressure. Do not drive if these symptoms occur.
Kidney

Kidney

SAFE IF PRESCRIBED
Valsazem 40 Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.
Liver

Liver

SAFE IF PRESCRIBED
Valsazem 40 Tablet is safe to use in patients with liver disease. No dose adjustment is recommended.

Interaction with drugs

Taking Valsazem with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Tacrolimus (Oral Route)

If concurrent use is essential, your doctor may monitor your kidney function and potassium levels closely.
Severe

Amiloride (Oral Route)

Do not consume Valsartan with Amiloride if you have kidney disorders. If concurrent use is essential, your doctor may monitor your potassium levels closely. and adjust the dose of Amiloride as per the observations.
Severe

Co-trimoxazole (Oral Route)

Do not consume Valsartan with Co-trimoxazole. If concurrent use is essential, please consult your doctor. They may monitor your potassium levels closely.
Severe

Eplerenone (Oral Route)

If concurrent use is essential, watch out for symptoms such as muscle weakness, fatigue, cramps, nausea, vomiting, tingling, numbness or irregular heartbeat and consult your doctor if you experience them. They may also monitor your potassium levels closely.
Severe

Spironolactone (Oral Route)

If concurrent use is essential, watch out for symptoms such as dizziness, fatigue, confusion, weight loss, tingling in hands and feet, nausea, diarrhea, loss of appetite, difficulty concentrating, or taste changes, and consult your doctor if you experience them. They may adjust the doses as per the observations.

Frequently asked questions

A substantial decrease in blood pressure can be experienced within 2 weeks of starting Valsazem 40 Tablet. The medicine may take up to 4 weeks to show its complete effects.
There are many blood pressure-lowering medicines which can be considered safe. Use of these medicines varies from person to person and can be based on various factors such as age, gender, other co-existing diseases, etc. For instance, a person below 55 years of age having no other coexisting disease may be prescribed angiotensin II receptor antagonists (ARAs) (e.g., Valsazem 40 Tablet, losartan, olmesartan) or Angiotensin Converting Enzyme (ACE) Inhibitors (e.g., ramipril, captopril, or enalapril) by the doctor.
Valsazem 40 Tablet does not generally affect the working of a proper functioning kidney. However, it should be cautiously used in patients who have existing severe kidney impairment (creatinine clearance <10 ml/min) and are on dialysis as there is limited data to support the safety of these patients.
Valsazem 40 Tablet belongs to a group of medicines called angiotensin II receptor antagonists (ARAs). Angiotensin II is a substance in the body that causes vessels to tighten which leads to increase in blood pressure. Valsazem 40 Tablet works by blocking the effect of angiotensin II. As a result, blood vessels relax and blood pressure is lowered.
No, Valsazem 40 Tablet does not cause weight gain as a side effect. However, if your kidney function deteriorates, then your body may swell due to accumulation of water (fluid retention) because of which you may gain weight. Inform your doctor if you experience any unexplained weight gain or swelling in your feet, ankles, or hands.
Continue taking Valsazem 40 Tablet as long as your doctor has prescribed. Do not stop taking it even if you start feeling better. You may even have to take it life long, since Valsazem 40 Tablet does not cure high blood pressure or heart failure but controls them.
Taking Valsazem 40 Tablet during the last months of pregnancy can cause serious harm or even death of the unborn baby. Inform your doctor if you are pregnant or plan to become pregnant. Do not take Valsazem 40 Tablet if you are pregnant. If you become pregnant while taking Valsazem 40 Tablet, stop taking Valsazem 40 Tablet and call your doctor immediately.
No, do not switch to a different Valsazem 40 Tablet product unless your doctor says that you should. Since you have to take it daily, keep a stock of it. Each Valsazem 40 Tablet product releases the medication differently in your body and cannot be used interchangeably.

Fact Box

Chemical Class

Valine derivative

Habit Forming

No

Therapeutic Class

CARDIAC

Action Class

Angiotensin Receptor Blockers (ARBs)

Related lab tests

References

  1. Hilal-Dandan R. Renin and Angiotensin. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 736-39
  2. Pfeffer MA, Opie LH. Inhibitors of the Renin-Angiotensin-Aldosterone System. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 157-58.
  3. Benowitz NL. Antihypertensive Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 183.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1457-58.
  5. Valsartan. East Hanover, New Jersey: Novartis Pharmaceuticals Corp.; 1996 [revised Feb. 2011]. [Accessed 20 Mar. 2019] (online) Available from:
  6. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Valsartan. [Updated 2020 Jan 20]. [Accessed 19 Feb. 2020] (online) Available from:
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
  8. Valsartan [Product Information Sheet]. East Hanover, NJ: Novartis Pharmaceuticals Corporation. 2025. [Accessed 19 Jan. 2026] (online). Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zeelab Pharmacy Pvt Ltd
Address: 913, D-104, Pitampura, Delhi-110034

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Country of origin: India
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