Usroliv 300mg Tablet is used to dissolve certain gallstones and prevent them from forming. It is also used to treat a type of liver disease called primary biliary cirrhosis. It helps break down the cholesterol that has converted into stones in your gallbladder thereby dissolving the stones.

Usroliv 300mg Tablet should be swallowed whole after a meal and with a glass of milk or water. The dose will depend on what you are being treated for and your body weight. Take it regularly to get maximum benefit and keep taking it for as long as prescribed (several months or longer). Keep taking it even if your symptoms disappear.

This medicine's most common side effects are abdominal pain, diarrhea, hair loss, itching, nausea, and rash. Not everyone gets these side effects. If you are worried about them, or they do not go away, let your doctor know.

Before taking this medicine, you should tell your doctor if you have an inflammation of the gallbladder or bile ducts, you get frequent cramp-like pain in your upper abdomen, you have been coughing up blood or you have gained weight rapidly. Using this medicine can reduce or increase the effect of some other medicines so tell your doctor all other medicines you are taking. Women should discontinue hormonal birth control pills as they can increase the production of gallstones. During the treatment, you may need ultrasound scans, or frequent blood tests to check your liver function.

Uses of Usroliv Tablet

Treatment of Primary biliary cirrhosis
Treatment of Gallbladder stones

Benefits of Usroliv Tablet

In Treatment of Primary biliary cirrhosis

Primary biliary cholangitis is a type of liver disease that gradually gets worse over time. It does not always have symptoms but, over time, it can lead to liver failure. Usroliv 300mg Tablet is used to treat this condition and may be used by itself or with other medicines. It can help prevent or delay liver damage in most people, especially if you start taking it in the early stages. Once you start this treatment, you will likely be taking it for the rest of your life. To make the medicine more effective and for general health benefits, you can help yourself by stopping smoking, keeping a healthy weight, and not drinking too much alcohol.

In Treatment of Gallbladder stones

Usroliv 300mg Tablet is a medicine that helps decreases the amount of cholesterol produced by your liver. It helps to break down cholesterol that has formed into “stones” in the gallbladder. It may take several months to completely dissolve the stone, so you need to take the medicine regularly and as long as the doctor has prescribed it for it to be effective. There might be other medicines and certain lifestyle changes that can reduce your cholesterol level and make gallstones less likely, consult with your doctor.

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Side effects of Usroliv Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Usroliv

Abdominal pain
Diarrhea
Hair loss
Itching
Nausea
Rash

How to use Usroliv Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Usroliv 300mg Tablet is to be taken with food.

How Usroliv Tablet works

Usroliv 300mg Tablet is a hepatoprotective medication. It works by reducing the amount of cholesterol in the blood and helps dissolve gallbladder stones that are composed mainly of cholesterol. It also improves liver enzymes, protects liver cells from injury caused due to toxic bile acids, and improves liver function.

Safety advice

Alcohol

UNSAFE

Usroliv 300mg Tablet may cause excessive drowsiness with alcohol.

Pregnancy

SAFE IF PRESCRIBED

Usroliv 300mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

SAFE IF PRESCRIBED

Usroliv 300mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

SAFE

Usroliv 300mg Tablet does not usually affect your ability to drive.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Usroliv 300mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Usroliv 300mg Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Usroliv Tablet?

If you miss a dose of Usroliv 300mg Tablet, skip it and continue with your normal schedule. Do not double the dose.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Usroliv 300mg Tablet

₹31.0/Tablet

Ursolid 300mg Tablet

Leeford Healthcare Ltd

₹25.9/tablet

16% cheaper

Livetone UD 300mg Tablet

Cipla Ltd

₹25.7/tablet

17% cheaper

Ursobiac Tablet

Mylan Pharmaceuticals Pvt Ltd - A Viatris Company

₹29/tablet

6% cheaper

Ursocol 300 Tablet

Sun Pharmaceutical Industries Ltd

₹41.47/tablet

34% costlier

Udimit 300 Tablet

Vintek Pharmaceuticals

₹38.8/tablet

25% costlier

View all substitutes

Quick tips

Usroliv 300mg Tablet should be taken after a meal with a glass of milk or water.
Eat a healthy diet, exercise regularly, and avoid alcohol intake.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools.
Your doctor may monitor your liver function and bilirubin levels every month for the next 3 months after the start of therapy, and every 6 months thereafter.
Do not stop taking the medication without talking to your doctor.

Fact Box

Chemical Class

Bile Acids and Salts

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Hepatoprotectives

Interaction with drugs

Taking Usroliv with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Bezafibrate (Oral Route) Moderate

Bezafibrate may reduce the efficacy of Ursodeoxycholic Acid. Do not consume Ursodeoxycholic Acid with Bezafibrate. If concurrent use is essential, your doctor may monitor the effe... More

Cholestyramine (Oral Route) Moderate

Cholestyramine may reduce blood levels of Ursodeoxycholic Acid. Ensure a gap of at least 2 hours between taking Ursodeoxycholic Acid and Cholestyramine. Your doctor may monitor th... More

Colesevelam (Oral Route) Moderate

Colesevelam may reduce blood levels of Ursodeoxycholic Acid. Ensure a gap of at least 4 hours between taking Ursodeoxycholic Acid and Colesevelam. Your doctor may monitor your tre... More

Conjugated Estrogens (Oral Route) Moderate

Concurrent use may promote gallstone formation. Careful consideration is advised when taking Ursodeoxycholic Acid with Conjugated Estrogens. Your doctor may monitor your treatment... More

Allylestrenol (Oral Route) Moderate

Concurrent use may promote gallstone formation. Careful consideration is advised when taking Ursodeoxycholic Acid with Allylestrenol. Your doctor may monitor your treatment and ad... More

View all drug interactions

Patient concerns

Sir ! For gallbladder stones medicine pl!

Dr. Deepak Kumar Soni

Ayurveda

https://goo.gl/forms/TPKaRvl1NqrBq4Zj2

Suffering from chronic liver parenchymal disease since last three months is it curable and what food habit will follow?

Dr. Sfurti Mann

Internal Medicine

Liver cirrhosis can not be cured. Cause of liver cirrhosis needs to be worked up as well as upper GI endoscopy to look for varies. Avoid alcohol & pain killers .

FAQs

When should I take Usroliv 300mg Tablet?

The suitable timing of taking this medicine might differ depending upon your condition. Your doctor might instruct you to take 2 to 3 doses per day and suggest to take the last dose at bedtime. Usroliv 300mg Tablet should be taken with water milk and can be taken with food or after food. When prescribed for dissolving gallstones, it is usually suggested to be taken once daily at night. Ideally, it should be taken at a gap of 6 hours, for example at 8 am, 2 pm and 8 pm.

Is Usroliv 300mg Tablet safe?

Usroliv 300mg Tablet is usually considered to be a safe and effective medicine. However, this medicine may have some common side effects, such as diarrhea. If diarrhea occurs, your doctor may reduce the dose and if it persists, your treatment may be discontinued. Additionally, using this medicine as a long-term therapy may also affect your liver enzyme levels. To keep a check on this, your doctor will keep monitoring your liver enzyme levels regularly. Despite these minor side effects, this medicine is supposed to be a good alternative to surgery in some patients with gallstones.

How does Usroliv 300mg Tablet help the liver?

Usroliv 300mg Tablet acts on the liver and gets concentrated in the bile secreted from the liver. This, as a result, suppresses the synthesis and secretion of cholesterol by the liver, thereby decreasing the cholesterol levels in bile. This medicine also acts by stopping the intestines from absorbing the bile salts and cholesterol. So, the reduced cholesterol saturation in the bile from the liver leads to the gradual dissolving of cholesterol from gallstones, leading to a decrease in size and their eventual dissolution. It also reduces elevated liver enzyme levels by increasing the bile flow through the liver, hence protecting the liver cells.

Does Usroliv 300mg Tablet cause weight gain?

Yes, there is a chance of weight gain with Usroliv 300mg Tablet, but it is not common. The use of Usroliv 300mg Tablet can cause weight gain when prescribed in patients with liver disease associated with chronic stasis of bile in small bile ducts of the liver. In such condition, bile cannot flow from the liver to the small intestine. Again, the chance of weight gain varies from person to person depending upon the disease, so consult your doctor if you experience weight gain.

What should I avoid while taking Usroliv 300mg Tablet?

While taking Usroliv 300mg Tablet, avoid taking an antacid preparation without consulting your doctor, as they decrease the effectiveness of Usroliv 300mg Tablet. You should also avoid medicines like cholestyramine or colestipol as they affect the effectiveness of Usroliv 300mg Tablet. So, ask your doctor about the time gap that should be maintained between Usroliv 300mg Tablet and these medicines. Also, avoid taking oral contraceptives, estrogenic hormones and blood cholesterol-lowering agents such as clofibrate as they may increase the chances of developing gallstones and act opposite to the Usroliv 300mg Tablet.

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Related lab tests

Liver Function Test

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Ursodiol. Birmingham, Alabama: Axcan Pharma US, Inc.; 1997 [revised Nov. 2009]. [Accessed 25 Jan. 2019] (online) Available from:
Ursodiol. Bridgewater, New Jersey: Aptalis Pharma US, Inc.; 1997 [revised Jun. 2013]. [Accessed 28 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Ursodiol. [Updated 2020 Jan 20]. [Accessed 20 Feb. 2020] (online) Available from:
Ursodeoxycholic [Package Insert]. Mumbai, India: Alkem Laboratories Ltd.; 2016. [Accessed 07 Aug. 2023]. (online) Available from:
The Lancet. Gastroenterology and Hepatology. [Accessed 07 Aug. 2023]. (online) Available from:

Marketer details

Name: Dr Kumars Pharmaceuticals

Address: SCF 421, Ist Floor, Motor Market, Manimajra Chandigarh-160047,India

Country of origin: India

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