Ursocad Plus Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 07 Apr 2026 | 11:10 AM (IST)

Ursocad Plus Tablet is used to treat cholesterol gallstones, primary biliary cirrhosis, primary sclerosing cholangitis, and liver disease associated with cystic fibrosis. It works by improving bile flow and breaking down excess cholesterol in bile, helping dissolve gallstones and protect the liver from damage.

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Ursodeoxycholic Acid (NA)

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General Information

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Store below 30°C

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Product introduction

Take Ursocad Plus Tablet after a meal and with a glass of milk or water. The dose will depend on what you are being treated for and your health condition. Take it regularly to get maximum benefit, and keep taking it for as long as prescribed (several months or longer). Keep taking it even if your symptoms disappear.

The most common side effects of Ursocad Plus Tablet are abdominal pain, diarrhea, hair loss, itching, nausea, and rash. Not everyone gets these side effects. If you are worried about them or they do not go away, let your doctor know. They may be able to suggest ways to manage them or prescribe an alternative medicine.

Before taking this medicine, tell your doctor if you have gallbladder or bile duct inflammation, frequent cramp-like pain in your upper abdomen, blood in your cough, or rapid weight gain. Using this medicine can increase or decrease the effects of other medicines, so tell your doctor about all the other medicines you are taking. Pregnant and breastfeeding women should consult their doctor before using this medicine to make sure it is safe for them.

Uses of Ursocad Tablet

Treatment of Gallbladder stones
Treatment of Primary biliary cirrhosis

Benefits of Ursocad Tablet

Treatment of Gallbladder stones
Ursocad Plus Tablet is a medicine that helps decreases the amount of cholesterol produced by your liver. It helps to break down cholesterol that has formed into “stones” in the gallbladder. It may take several months to completely dissolve the stone, so you need to take the medicine regularly and as long as the doctor has prescribed it for it to be effective. There might be other medicines and certain lifestyle changes that can reduce your cholesterol level and make gallstones less likely, consult with your doctor.

Treatment of Primary biliary cirrhosis
Primary biliary cirrhosis is a condition where bile ducts in the liver are damaged, leading to bile buildup. Ursocad Plus Tablet helps improve bile flow and reduce liver inflammation. This slows disease progression and relieves symptoms such as fatigue and itching. Take it regularly to support long-term liver function.

Side effects of Ursocad Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ursocad

Abdominal pain
Diarrhea
Nausea
Rash
Hair loss
Cough
Sinus inflammation
Upper respiratory tract infection
Urinary tract infection
Allergy
Chest pain
Dyspepsia
Abdominal discomfort
Headache
Itching
Back pain
Fatigue
Flatulence
Vomiting
Joint pain
Joint inflammation
Muscle pain
Insomnia (difficulty in sleeping)
Bronchitis (inflammation of the airways)

How to use Ursocad Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ursocad Plus Tablet should be taken with or after food.

How Ursocad Tablet works

Ursocad Plus Tablet is a hepatoprotective medication. It works by reducing the amount of cholesterol in the blood and helps dissolve gallbladder stones that are composed mainly of cholesterol. It also improves liver enzymes, protects liver cells from injury caused due to toxic bile acids, and improves liver function.

All substitutes for Ursocad Plus Tablet

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HEPAkind Tablet

by Mankind Pharma Ltd

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Quick tips

Take Ursocad Plus Tablet after a meal with a glass of milk or water to help improve its absorption and reduce stomach upset.
Take Ursocad Plus Tablet regularly at the same time each day, as it works gradually and may take time to show beneficial results.
Follow a healthy diet and exercise regularly, and avoid alcohol while taking Ursocad Plus Tablet.
Avoid heavy or oily meals, as high-fat foods may worsen gallbladder or liver-related symptoms.
Diarrhea may occur as a side effect. Drink plenty of fluids, including oral rehydration solution (ORS), and inform your doctor if it persists or if you notice blood in your stools.
Your doctor may monitor liver function tests and bilirubin levels regularly, especially during the first few months of the treatment.
Seek medical advice promptly if you develop worsening jaundice, severe itching, dark urine, pale stools, persistent abdominal pain, or fever.
Do not stop taking Ursocad Plus Tablet without consulting your doctor, as liver conditions often require monitored and continuous therapy.
Inform your doctor about all other medicines, herbal products, or supplements you are taking to avoid potential interactions.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Ursocad Plus Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Ursocad Plus Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Ursocad Plus Tablet during breastfeeding is not available. Please consult your doctor.

Driving

SAFE

Ursocad Plus Tablet does not usually affect your ability to drive.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Ursocad Plus Tablet in patients with kidney disease. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Ursocad Plus Tablet is safe to use in patients with liver disease. No dose adjustment is recommended.

Interaction with drugs

Taking Ursocad with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Magaldrate (Oral Route)

Ensure a gap of at least 2 hours between taking Ursodeoxycholic Acid and Magaldrate.

Moderate

Allylestrenol (Oral Route)

Careful consideration is advised when taking Ursodeoxycholic Acid with Allylestrenol. Your doctor may monitor your treatment and adjust the doses as per the observations.

Moderate

Bezafibrate (Oral Route)

Do not consume Ursodeoxycholic Acid with Bezafibrate. If concurrent use is essential, your doctor may monitor the effects of Ursodeoxycholic Acid along with your overall treatment and adjust the doses as per the observations. Bezafibrate may reduce the efficacy of Ursodeoxycholic Acid.

Moderate

Cholestyramine (Oral Route)

Ensure a gap of at least 2 hours between taking Ursodeoxycholic Acid and Cholestyramine. Your doctor may monitor the effects of Ursodeoxycholic Acid. Cholestyramine may reduce blood levels of Ursodeoxycholic Acid.

Moderate

Colesevelam (Oral Route)

Ensure a gap of at least 4 hours between taking Ursodeoxycholic Acid and Colesevelam. Your doctor may monitor your treatment and adjust the doses as per the observations. Colesevelam may reduce blood levels of Ursodeoxycholic Acid.

Frequently asked questions

How should Ursocad Plus Tablet be taken to ensure maximum absorption?

Ursocad Plus Tablet should usually be taken with food or milk to help your body absorb it better and to reduce the chance of stomach upset. Taking it at the same time every day helps maintain a steady level of the medicine in your body. If you consume antacids that contain aluminum, they may interfere with how well Ursocad Plus Tablet is absorbed. Taking it with a moderately high-fat meal (e.g., meals containing milk, curd, nuts, or oils) may further help in the absorption of ursodeoxycholic acid by promoting bile secretion.

What are the side effects of Ursocad Plus Tablet?

Ursocad Plus Tablet is generally well tolerated. Common side effects include diarrhea (most frequent), nausea, and abdominal discomfort. These are usually mild and temporary. Rarely, it may alter liver enzyme levels, especially with long-term use, so your doctor may recommend periodic monitoring.

What is Ursocad Plus Tablet and what is it used for?

Ursocad Plus Tablet contains ursodeoxycholic acid and is mainly used to dissolve certain cholesterol gallstones and to treat liver diseases such as primary biliary cholangitis. It works by lowering cholesterol levels in bile, improving bile flow, and protecting liver cells from damage. This can help reduce elevated liver enzyme levels and support overall liver function. It should only be used after proper evaluation and diagnosis by your doctor.

Does Ursocad Plus Tablet cause weight gain?

Although uncommon, Ursocad Plus Tablet may lead to weight gain, which has been reported in some patients with specific liver conditions, where bile flow was reduced. The likelihood varies depending on the underlying diseases and individual response. If you notice unexpected weight gain while taking Ursocad Plus Tablet, please consult your doctor.

What should be avoided while taking Ursocad Plus Tablet?

While taking Ursocad Plus Tablet, avoid certain medications, such as antacids, cholestyramine, and colestipol, as they may reduce its effectiveness. Hormonal medications that contain estrogen and drugs such as clofibrate may increase the risk of gallstones and interfere with the treatment. Alcohol should be limited or avoided because it can strain the liver and reduce the protective effects of Ursocad Plus Tablet. Always inform your doctor about all medications, supplements, and your lifestyle habits.

Can the body become resistant to Ursocad Plus Tablet?

The body typically does not develop resistance to Ursocad Plus Tablet, unlike with antibiotics. However, if gallstones become hardened with calcium and do not dissolve with Ursocad Plus Tablet, or if bile flow does not improve and liver enzyme levels remain elevated, it may indicate progression of the underlying condition.

Are there specific food interactions with Ursocad Plus Tablet?

There are no strict food restrictions while taking Ursocad Plus Tablet, but it is best to avoid very greasy or spicy foods, as they can trigger gallbladder discomfort and worsen symptoms. A balanced, high-fiber diet may support digestion and overall treatment effectiveness. Always follow any specific dietary recommendations your doctor provides.

How does Ursocad Plus Tablet dissolve gallstones?

Ursocad Plus Tablet works by altering bile composition in the gallbladder, creating conditions that allow cholesterol gallstones to slowly dissolve back into liquid bile. This process is gradual and only works for stones primarily made of cholesterol. The gallbladder must still be functioning properly for treatment to be effective. Your doctor may recommend periodic ultrasounds to monitor the treatment progress.

How long can I safely take Ursocad Plus Tablet?

The duration of treatment with Ursocad Plus Tablet depends on your medical condition and response to therapy. For fatty liver disease, it may be prescribed for a few months, while chronic conditions such as primary biliary cholangitis may require long-term use. When taken under medical supervision, Ursocad Plus Tablet is generally safe for extended treatment. Regular blood tests and imaging studies may be needed to monitor your liver function and ensure ongoing safety and effectiveness.

Can Ursocad Plus Tablet affect your skin or hydration?

In rare cases, Ursocad Plus Tablet may cause dry skin or a mild rash. Staying well hydrated supports overall health and liver function. Drinking adequate fluids and using a gentle moisturizer may help if mild dryness occurs. If you experience a severe skin reaction, stop taking Ursocad Plus Tablet and contact your doctor immediately.

What warning signs should you watch out for?

You should seek immediate medical attention if you develop severe right-sided abdominal pain, intense yellowing of the skin or eyes (jaundice), or severe and persistent diarrhea. These symptoms may indicate a blocked bile duct or a rare, serious reaction. Any unusual or worsening symptoms should be reported to your doctor promptly.

Fact Box

Chemical Class

Dihydroxy bile acid derivative

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Hepatoprotective Agents

Related lab tests

Liver Function Test

References

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cadila Pharmaceuticals Ltd
Address: Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, INDIA.

Vendor Details

Country of origin: India

Lab tests offered by us

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Ursocad Plus Tablet

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General Information

Contains

Salt Synonyms

Marketer

Storage

Product introduction

Uses of Ursocad Tablet

Benefits of Ursocad Tablet

Side effects of Ursocad Tablet

How to use Ursocad Tablet

How Ursocad Tablet works

All substitutes for Ursocad Plus Tablet

HEPAkind Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Magaldrate (Oral Route)

Allylestrenol (Oral Route)

Bezafibrate (Oral Route)

Cholestyramine (Oral Route)

Colesevelam (Oral Route)

Frequently asked questions

How should Ursocad Plus Tablet be taken to ensure maximum absorption?

What are the side effects of Ursocad Plus Tablet?

What is Ursocad Plus Tablet and what is it used for?

Does Ursocad Plus Tablet cause weight gain?

What should be avoided while taking Ursocad Plus Tablet?

Can the body become resistant to Ursocad Plus Tablet?

Are there specific food interactions with Ursocad Plus Tablet?

How does Ursocad Plus Tablet dissolve gallstones?

How long can I safely take Ursocad Plus Tablet?

Can Ursocad Plus Tablet affect your skin or hydration?

What warning signs should you watch out for?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Liver Function Test

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests