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Urdowell 300 Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 25 Nov 2025 | 03:05 PM (IST)
Urdowell 300 Tablet is a medicine used to dissolve certain gallstones and prevent them from forming. It helps break down the cholesterol that has converted into stones in your gallbladder, thereby dissolving the stones. It is also used to treat a type of liver disease called primary biliary cirrhosis.
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Urdowell 300 Tablet is currently sold out
Same composition alternative:
Livetone UD 300mg Tablet
₹330₹387.2
Available alternative from Cipla
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Urdowell 300 Tablet
Urdowell 300 Tablet
strip of 10 tablets
₹298
₹337.5
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Same composition
Livetone UD 300mg Tablet
Livetone UD 300mg Tablet
strip of 10 tablets
Ursodeoxycholic Acid (300mg)
by Cipla Ltd
Get by 6pm, Tomorrow
₹330
₹28.1 per tablet

₹281

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₹1200

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General Information

Contains

Ursodeoxycholic Acid (300mg)

Salt Synonyms

Ursodiol

Marketer

Abrowell Pharmaceuticals

Storage

Store below 25°C
The content is shown in English
Urdowell 300 Tablet image
Urdowell 300 Tablet image
Urdowell 300 Tablet image
Urdowell 300 Tablet image

Product introduction

Urdowell 300 Tablet should be swallowed whole after a meal and with a glass of milk or water. The dose will depend on what you are being treated for and your health condition. Take it regularly to get maximum benefit, and keep taking it for as long as prescribed (several months or longer). Keep taking it even if your symptoms disappear.


The most common side effects of Urdowell 300 Tablet are abdominal pain, diarrhea, hair loss, itching, nausea, and rash. Not everyone gets these side effects. If you are worried about them or they do not go away, let your doctor know. They may be able to suggest ways to manage them or prescribe an alternative medicine.


Before taking this medicine, you should tell your doctor if you have an inflammation of the gallbladder or bile ducts, frequent cramp-like pain in your upper abdomen, coughing up blood, or gaining weight rapidly. Using this medicine can reduce or increase the effect of some other medicines, so tell your doctor about all the other medicines you are taking. Pregnant and breastfeeding women should consult their doctor before using this medicine to make sure it is safe for them.

Uses of Urdowell Tablet

Benefits of Urdowell Tablet

Treatment of Gallbladder stones
Urdowell 300 Tablet is a medicine that helps decreases the amount of cholesterol produced by your liver. It helps to break down cholesterol that has formed into “stones” in the gallbladder. It may take several months to completely dissolve the stone, so you need to take the medicine regularly and as long as the doctor has prescribed it for it to be effective. There might be other medicines and certain lifestyle changes that can reduce your cholesterol level and make gallstones less likely, consult with your doctor.
Treatment of Primary biliary cirrhosis
Primary biliary cholangitis is a type of liver disease that gradually gets worse over time. It does not always have symptoms but, over time, it can lead to liver failure. Urdowell 300 Tablet is used to treat this condition and may be used by itself or with other medicines. It can help prevent or delay liver damage in most people, especially if you start taking it in the early stages. Once you start this treatment, you will likely be taking it for the rest of your life. To make the medicine more effective and for general health benefits, you can help yourself by stopping smoking, keeping a healthy weight, and not drinking too much alcohol.

Side effects of Urdowell Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Urdowell
  • Abdominal pain
  • Diarrhea
  • Nausea
  • Rash
  • Hair loss
  • Cough
  • Sinus inflammation
  • Upper respiratory tract infection
  • Urinary tract infection
  • Allergy
  • Chest pain
  • Dyspepsia
  • Abdominal discomfort
  • Headache
  • Itching
  • Back pain
  • Fatigue
  • Flatulence
  • Vomiting
  • Joint pain
  • Joint inflammation
  • Muscle pain
  • Insomnia (difficulty in sleeping)
  • Bronchitis (inflammation of the airways)

How to use Urdowell Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Urdowell 300 Tablet should be taken with or after food.

How Urdowell Tablet works

Urdowell 300 Tablet is a hepatoprotective medication. It works by reducing the amount of cholesterol in the blood and helps dissolve gallbladder stones that are composed mainly of cholesterol. It also improves liver enzymes, protects liver cells from injury caused due to toxic bile acids, and improves liver function.

All substitutes for Urdowell 300 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Ursolid 300mg Tablet

by Leeford Healthcare Ltd
₹31.2/tablet
5% costlier
<h3 class=bodySemiBold>Ursolid 300mg Tablet</h3>

Udinol 300mg Tablet

by Knoll Pharmaceuticals Ltd
₹37.3/tablet
25% costlier
<h3 class=bodySemiBold>Udinol 300mg Tablet</h3>

Udiliv 300 Tablet

by Abbott
₹57.87/tablet
94% costlier
<h3 class=bodySemiBold>Udiliv 300 Tablet</h3>

Actibile 300 Tablet

by Zydus Cadila
₹43/tablet
44% costlier
<h3 class=bodySemiBold>Actibile 300 Tablet</h3>

Ursetor 300 Tablet

by Torrent Pharmaceuticals Ltd
₹41.3/tablet
39% costlier
<h3 class=bodySemiBold>Ursetor 300 Tablet</h3>

Quick tips

  • Urdowell 300 Tablet should be taken after a meal with a glass of milk or water.
  • Eat a healthy diet, exercise regularly, and avoid alcohol intake.
  • Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools.
  • Your doctor may monitor your liver function and bilirubin levels every month for the next 3 months after the start of therapy and every 6 months thereafter.
  • Do not stop taking the medication without talking to your doctor.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Urdowell 300 Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Urdowell 300 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Urdowell 300 Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

SAFE
Urdowell 300 Tablet does not usually affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Urdowell 300 Tablet in patients with kidney disease. Please consult your doctor.
Liver

Liver

CAUTION
Urdowell 300 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Urdowell with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Magaldrate (Oral Route)

Ensure a gap of at least 2 hours between taking Ursodeoxycholic Acid and Magaldrate.
Moderate

Allylestrenol (Oral Route)

Careful consideration is advised when taking Ursodeoxycholic Acid with Allylestrenol. Your doctor may monitor your treatment and adjust the doses as per the observations.
Moderate

Bezafibrate (Oral Route)

Do not consume Ursodeoxycholic Acid with Bezafibrate. If concurrent use is essential, your doctor may monitor the effects of Ursodeoxycholic Acid along with your overall treatment and adjust the doses as per the observations. Bezafibrate may reduce the efficacy of Ursodeoxycholic Acid.
Moderate

Cholestyramine (Oral Route)

Ensure a gap of at least 2 hours between taking Ursodeoxycholic Acid and Cholestyramine. Your doctor may monitor the effects of Ursodeoxycholic Acid. Cholestyramine may reduce blood levels of Ursodeoxycholic Acid.
Moderate

Colesevelam (Oral Route)

Ensure a gap of at least 4 hours between taking Ursodeoxycholic Acid and Colesevelam. Your doctor may monitor your treatment and adjust the doses as per the observations. Colesevelam may reduce blood levels of Ursodeoxycholic Acid.

Frequently asked questions

The suitable timing of taking this medicine might differ depending on your condition. Your doctor might instruct you to take 2 to 3 doses per day and suggest taking the last dose at bedtime. Urdowell 300 Tablet should be taken with water or milk after food. When prescribed for dissolving gallstones, it is usually suggested to be taken once daily at night.
Urdowell 300 Tablet is usually considered to be a safe and effective medicine. However, this medicine may have some common side effects, such as diarrhea. If diarrhea occurs, your doctor may reduce the dose, and if it persists, your treatment may be discontinued. Additionally, using this medicine as a long-term therapy may also affect your liver enzyme levels. To keep a check on this, your doctor will keep monitoring your liver enzyme levels regularly. Despite these minor side effects, this medicine is supposed to be a good alternative to surgery in some patients with gallstones.
Urdowell 300 Tablet acts on the liver and gets concentrated in the bile secreted from the liver. This, as a result, suppresses the synthesis and secretion of cholesterol by the liver, thereby decreasing the cholesterol levels in bile. This medicine also acts by stopping the intestines from absorbing the bile salts and cholesterol. So, the reduced cholesterol saturation in the bile from the liver leads to the gradual dissolving of cholesterol from gallstones, leading to a decrease in size and their eventual dissolution. It also reduces elevated liver enzyme levels by increasing the bile flow through the liver, hence protecting the liver cells.
Yes, there is a chance of weight gain with Urdowell 300 Tablet, but it is not common. The use of Urdowell 300 Tablet can cause weight gain when prescribed in patients with liver disease associated with chronic stasis of bile in the small bile ducts of the liver. In such conditions, bile cannot flow from the liver to the small intestine. Again, the chance of weight gain varies from person to person depending on the disease, so consult your doctor if you experience weight gain.
While taking Urdowell 300 Tablet, avoid taking an antacid preparation without consulting your doctor, as they decrease the effectiveness of Urdowell 300 Tablet. You should also avoid medicines like cholestyramine or colestipol, as they affect the effectiveness of Urdowell 300 Tablet. Ask your doctor about the time gap that should be maintained between Urdowell 300 Tablet and these medicines. Also, avoid taking oral contraceptives, estrogenic hormones, and blood cholesterol-lowering agents such as clofibrate, as they may increase the chances of developing gallstones and act opposite to the Urdowell 300 Tablet.
The suitable timing of taking this medicine might differ depending upon your condition. Your doctor might instruct you to take 2 to 3 doses per day and suggest to take the last dose at bedtime. Urdowell 300 Tablet should be taken with water milk and can be taken with food or after food. When prescribed for dissolving gallstones, it is usually suggested to be taken once daily at night. Ideally, it should be taken at a gap of 6 hours, for example at 8 am, 2 pm and 8 pm.
Urdowell 300 Tablet is usually considered to be a safe and effective medicine. However, this medicine may have some common side effects, such as diarrhea. If diarrhea occurs, your doctor may reduce the dose and if it persists, your treatment may be discontinued. Additionally, using this medicine as a long-term therapy may also affect your liver enzyme levels. To keep a check on this, your doctor will keep monitoring your liver enzyme levels regularly. Despite these minor side effects, this medicine is supposed to be a good alternative to surgery in some patients with gallstones.
Urdowell 300 Tablet acts on the liver and gets concentrated in the bile secreted from the liver. This, as a result, suppresses the synthesis and secretion of cholesterol by the liver, thereby decreasing the cholesterol levels in bile. This medicine also acts by stopping the intestines from absorbing the bile salts and cholesterol. So, the reduced cholesterol saturation in the bile from the liver leads to the gradual dissolving of cholesterol from gallstones, leading to a decrease in size and their eventual dissolution. It also reduces elevated liver enzyme levels by increasing the bile flow through the liver, hence protecting the liver cells.
Yes, there is a chance of weight gain with Urdowell 300 Tablet, but it is not common. The use of Urdowell 300 Tablet can cause weight gain when prescribed in patients with liver disease associated with chronic stasis of bile in small bile ducts of the liver. In such condition, bile cannot flow from the liver to the small intestine. Again, the chance of weight gain varies from person to person depending upon the disease, so consult your doctor if you experience weight gain.
While taking Urdowell 300 Tablet, avoid taking an antacid preparation without consulting your doctor, as they decrease the effectiveness of Urdowell 300 Tablet. You should also avoid medicines like cholestyramine or colestipol as they affect the effectiveness of Urdowell 300 Tablet. So, ask your doctor about the time gap that should be maintained between Urdowell 300 Tablet and these medicines. Also, avoid taking oral contraceptives, estrogenic hormones and blood cholesterol-lowering agents such as clofibrate as they may increase the chances of developing gallstones and act opposite to the Urdowell 300 Tablet.

Fact Box

Chemical Class

Dihydroxy bile acid derivative

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Hepatoprotective Agents

Related lab tests

Liver Function Test

References

  1. Ursodiol [Prescribing Information]. Birmingham, Alabama: Axcan Pharma US, Inc.; 2009. [Accessed 25 Jan. 2019] (online) Available from:
  2. Ursodiol [Prescribing Information]. Bridgewater, New Jersey: Aptalis Pharma US, Inc.; 2013. [Accessed 28 Mar. 2019] (online) Available from:
  3. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Ursodiol. [Updated 2020 Jan 20]. [Accessed 20 Feb. 2020] (online) Available from:
  4. Ursodeoxycholic [Package Insert]. Mumbai, India: Alkem Laboratories Ltd.; 2016. [Accessed 07 Aug. 2023]. (online) Available from:
  5. The Lancet. Gastroenterology and Hepatology. [Accessed 07 Aug. 2023]. (online) Available from:
  6. Ursodeoxycholic Acid [Package Insert]. Hertfordshire, UK: Glenmark Pharmaceuticals Europe Limited; 2019. [Accessed 03 Feb. 2025]. (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Abrowell Pharmaceuticals
Address: 8 ,Phase 1 ,Lotus Park ,Lohegaon,Pune,411015

Vendor Details

Country of origin: India

Lab tests offered by us

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