Upwardz 20mg Tablet

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TTK Healthcare Ltd

Composition for Upwardz 20mg Tablet

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Potentiallyunsafewith
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Alcohol
160
₹40.0/Tablet
4 tablets in 1 strip
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Medicine Overview of Upwardz Tablet

uses

Uses of Upwardz Tablet

Upwardz 20mg Tablet is used in the treatment of erectile dysfunction and pulmonary hypertension.
It is also used in erectile dysfunction with benign prostatic hyperplasia (enlarged prostate).
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Side effects of Upwardz Tablet

Common

Headache, Nausea, Nasopharyngitis, Flushing (sense of warmth in the face, ears, neck and trunk), Dyspepsia, Muscle pain, Back pain, Pain in extremity.

uses

How to use Upwardz Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It can be taken with or without food, but it is better to take Upwardz 20mg Tablet at a fixed time.

How Upwardz Tablet works

Upwardz 20mg tablet is a phosphodiesterase (PDE-5) inhibitor. It works in erectile dysfunction by increasing blood flow to the penis by relaxing the muscles in penile blood vessels. It works in pulmonary hypertension by relaxing the blood vessels in the lungs to allow blood to flow more easily.

In Depth Information on Upwardz Tablet

Expert advice for Upwardz Tablet

  • Upwardz helps to have and maintain an erection, but it will not produce the erection without sexual stimulation.
  • It should be taken just when you need it and one to half hour before sexual intercourse.
  • It can be taken with or without food.
  • You should not use if you have recently taken nitrates. Nitrates are commonly used in angina (chest pain).
  • Inform your doctor if the erection does not subside within two hours after sexual intercourse.
  • Inform your doctor if you experience any eye sight change while taking Upwardz.
  • Do not take Upwardz if you recently had a stroke, a heart attack or if you have severe liver disease or very low blood pressure (<90/50 mmHg).
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Warnings
Special precautions for Upwardz 20mg Tablet
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Alcohol
CAUTION
Tadalafil can lower blood pressure, and combining it with alcohol may further increase this effect.
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Pregnancy
PROBABLY SAFE
Upwardz 20mg Tablet is probably safe to use during pregnancy.

Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
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Lactation
No information is available on the use of Upwardz 20mg Table
t during lactation. Please consult your doctor.
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Driving
Upwardz 20mg Tablet may make you feel dizzy, sleepy, tired,
or decrease alertness. If this happens, do not drive.
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Kidney
CAUTION
Upwardz 20mg Tablet should be used with caution in patients
with kidney disease. Dose adjustment of Upwardz 20mg Tablet may be needed. Please consult your doctor.
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Liver
CAUTION
Upwardz 20mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Upwardz 20mg Tablet may be needed. Please consult your doctor.

Use of Upwardz 20mg Tablet is not recommended in patients with severe liver disease.
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Severely interacts with other drugs like
Myonit Injection, Glynit 2.6mg Tablet, Zynicor 5mg Tablet, New GTN 6.4mg Tablet

Missed Dosageuses

If you miss a dose of Tadalafil, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Patient Concerns

Frequently asked questions for Upwardz 20mg Tablet

Frequently asked questions for Tadalafil

No, Upwardz is not an addictive drug. However, some people may develop an emotional or psychological dependence on the medicine. Always take the medicine for the duration as suggested by your doctor.
Q. Can I take Upwardz with prednisone?
Upwardz, when taken with prednisone, may cause low blood pressure. Please consult your doctor for the change of dose regimen or an alternative drug of choice that may be required when the two medicines are to be used together.
Upwardz is safe when used strictly as advised by your doctor and for approved conditions like erectile dysfunction and pulmonary arterial hypertension. However, there are some very common side effects that you may experience with Upwardz like a headache, flushing, nasal congestion, dyspepsia, back pain, muscle pain, and pain in extremity.
Q. Is Upwardz better than sildenafil?
Both Upwardz and sildenafil belong to the same group of drugs called phosphodiesterase 5 inhibitors, used for the treatment of erectile dysfunction and pulmonary arterial hypertension. However, Upwardz has a slow onset of action with less efficacy but works for a much longer time and is safer than sildenafil.
Upwardz should only be taken only for the time period as advised by your doctor.
Q. Can I take Upwardz with losartan?
Yes, Upwardz can be taken with losartan. However, there could be an excessive fall in blood pressure when taken together and you can experience symptoms like dizziness, lightheadedness, fainting, flushing, headache, or an increased heart rate. So, special caution must be taken when taking them together and inform your doctor if you experience any of these symptoms.
Upwardz can be taken in patients with high blood pressure. However, if you are on medicines for high blood pressure, taking Upwardz along with them can cause a significant fall in blood pressure which could be harmful. Upwardz is absolutely contraindicated in patients taking nitrates. Inform your doctor before taking them together.
Q. Can I take Upwardz with antibiotics?
Upwardz can be taken safely with antibiotics. However, it is degraded in the body by an enzyme known as CYP3A4 and a dose adjustment may be needed when it is used with drugs which can affect the activity of this enzyme. Antibiotics like erythromycin, clarithromycin, ketoconazole and itraconazole can decrease the action of this enzyme and increase Upwardz levels in the blood. Antibiotics like rifampicin increase the action of this enzyme causing an increased breakdown of Upwardz and decrease its efficacy.
No, Upwardz has no known effect on sperm count. It is a medication used for erectile dysfunction, not to increase sperm count.
No, Upwardz is not known to affect ejaculation. It is used for the treatment of erectile dysfunction.
Like any other drug, Upwardz does have an expiry date and should not be used beyond that. Please check the package insert for the same.
Yes, Upwardz works very effectively for the treatment of erectile dysfunction and pulmonary arterial hypertension when taken strictly as advised by your doctor.
Generally, the effect of Upwardz lasts from 24 to 36 hours, however, the effect may vary from patient to patient. As it works for a long duration, its action may last for more than one day. Some patients call it a weekend pill which is when taken on Friday night, the effect may last until Sunday morning. So it is preferred over sildenafil and verdanafil by some patients.
No, Upwardz is not a steroid. It is a phosphodiesterase enzyme inhibitor and is used for treating erectile dysfunction.
Both Upwardz and sildenafil belong to the same group of drugs called phosphodiesterase 5 inhibitors, used for the treatment of erectile dysfunction and pulmonary arterial hypertension. However, Upwardz has a slow onset of action with less efficacy but works for a much longer time and is safer than sildenafil.
No, Upwardz is not a life long medicine. It should be taken only for a duration as advised by the doctor.
Upwardz is a prescription drug and should only be taken for the appropriate indication as prescribed by a doctor as it may be associated with many side effects. Also, it is available only on prescription by a doctor.
Q. Can I take Upwardz with tamsulosin?
When taken together, these drugs may produce an additive blood-pressure-lowering effect. Dose needs to be titrated carefully. Consult your doctor before taking them together.
Q. Can I take Upwardz with lisinopril?
Yes, Upwardz can be taken with lisinopril. However, there could be an excessive fall in blood pressure when taken together and you can experience symptoms like dizziness, lightheadedness, fainting, flushing, headache, or an increased heart rate. So, special caution must be taken when taking them together and inform your doctor if you experience any of these symptoms.
Q. Can I take Upwardz with metoprolol?
Yes, Upwardz can be taken with metoprolol. However, there could be an excessive fall in blood pressure when taken together and you can experience symptoms like dizziness, lightheadedness, fainting, flushing, headache, or an increased heart rate. So, special caution must be taken when taking them together and inform your doctor if you experience any of these symptoms.
Upwardz is not a cure for erectile dysfunction. It only helps in erection by relaxing penile smooth muscles and increasing blood flow.
No, Upwardz is not known to increase the size of the penis.
Upwardz can lower the blood pressure but does not have a significant effect. However, when used along with other medications which lower blood pressure, it can have an additional effect which can be harmful. Talk to your doctor in case you are taking blood pressure lowering medicines and you are also advised to take Upwardz.
Upwardz is not known to have any effect on testosterone levels. However, if your testosterone levels are low, then Upwardz may not be useful in treating erectile dysfunction.
Q. Can I take Upwardz with sildenafil?
Both Upwardz and sildenafil are phosphodiesterase inhibitors and act by dilating the blood vessels. Using them together would not give any additional benefit, rather they may cause a severe fall in blood pressure and a prolonged painful erection. Therefore, these two drugs should not be taken together.
Q. Can I take Upwardz when I am also taking bisoprolol?
Yes, Upwardz can be taken with bisoprolol. However, there could be an excessive fall in blood pressure when they are taken together and you can experience symptoms like dizziness, lightheadedness, fainting, flushing, headache, or an increased heart rate. So, special caution must be taken when taking both the drugs together and inform your doctor if you experience any of these symptoms.
Q. What will be the effect of using ibuprofen with Upwardz?
Yes,Upwardz can be taken with ibuprofen. It is used by many patients to relieve the headache caused by Upwardz. No drug-drug interactions or any harmful effects have been reported when they are used together.
Yes, there have been some reports where the patients have given the history of nose bleed (epistaxis) after taking Upwardz. Other drugs from the same class have also shown to cause nose bleeds in some patients.
Q. What is the difference between Upwardz and L-arginine?
Upwardz is used for the treatment of erectile dysfunction. It works by releasing nitrous oxide (NO) which relaxes the smooth muscles of the blood vessels and dilates them. L-arginine is an amino acid which is involved in the synthesis of nitric oxide (NO). So, it has been suggested that L-arginine can help in the treatment of erectile dysfunction. However, there is no regulatory approval for its use as of now.
Q. Are Upwardz and avanafil same?
No, Upwardz and avanafil are not same drugs but they belong to the same class of phosphodiesterase-5 (PDE5) inhibitors used for the treatment of erectile dysfunction. Upwardz is also used in the treatment of pulmonary arterial hypertension in lower doses. Upwardz is seen to be more efficacious, better tolerated and longer acting than avanafil. However, avanafil starts to show its effect faster than Upwardz.
Q. How is Upwardz different from vardenafil?
Both Upwardz and vardenafil are phosphodiesterase-5 (PDE5) inhibitors used in the treatment of erectile dysfunction (ED). Upwardz is also used in the treatment of pulmonary arterial hypertension in lower doses. Upwardz starts to act in 20 minutes but the action remains for almost 36 hours whereas vardenafil starts to act in 10 minutes and acts for almost 10 hours, respectively. Upwardz is less effective than vardenafil but safer.
Q. Is it safe to take Upwardz with amlodipine?
Yes, Upwardz can be taken with amlodipine. However, there could be an excessive fall in blood pressure they are when taken together and you can experience symptoms like dizziness, lightheadedness, fainting, flushing, headache, or an increased heart rate. So, special caution must be taken and inform your doctor if you experience any of these symptoms.
Q. Is it safe to take Upwardz with propranolol?
Yes, Upwardz can be taken with propranolol. However, there could be an excessive fall in blood pressure they are when taken together and you can experience symptoms like dizziness, lightheadedness, fainting, flushing, headache, or an increased heart rate. So, special caution must be taken and inform your doctor if you experience any of these symptoms.
Q. Can I take Upwardz when I am also taking atenolol for controlling my blood pressure?
Yes, Upwardz can be taken with atenolol. However, there could be an excessive fall in blood pressure they are when taken together and you can experience symptoms like dizziness, lightheadedness, fainting, flushing, headache, or an increased heart rate. So, special caution must be taken and inform your doctor if you experience any of these symptoms.
Q. Is it safe to take Upwardz when I am also taking fluconazole?
Upwardz can be taken with fluconazole, however, a dose adjustment would be needed before taking them together. Upwardz is metabolized (degraded) by an enzyme known as CYP3A4. Fluconazole decreases the working of this enzyme causing increased blood levels of Upwardz and higher chances of having side effects.
Q. Is Upwardz safe to use in patients with glaucoma?
Yes, Upwardz can be used by patients with glaucoma. But you must inform your doctor before using this medicine. It has been found to increase the intraocular pressure in animals whereas the same is not seen in humans. However, other medicines of this class have been reported to cause increase intraocular pressure in healthy human beings.
Q. Is it safe to take Upwardz with dapoxetine?
Yes, Upwardz can be safely taken with dapoxetine. Upwardz is useful for treating erectile dysfunction and dapoxetine is for premature ejaculation. A fixed dose combination of these medicines is available which is useful in patients suffering from both erectile dysfunction and premature ejaculation. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Can I use Upwardz with nitroglycerin?
Use of Upwardz is not recommended in patients taking nitrates like nitroglycerin as their combined use can cause a severe fall in blood pressure, which can also result in death. It is advisable to keep a time gap of 24 hours between the intake of Upwardz and any nitrate substance.
Q. What is the benefit of taking Upwardz with finasteride?
Yes, Upwardz can be taken along with finasteride. This combination is beneficial in the treatment of benign prostatic hyperplasia (BPH). Finasteride is also known to cause erectile dysfunction as one of its side effects and Upwardz can be used for the treatment of this problem along with finasteride.
Upwardz can be taken with grapefruit juice, however, a dose adjustment would be needed before taking them together. Upwardz is metabolized (degraded) by an enzyme known as CYP3A4. Grapefruit juice decreases the working of this enzyme, increases blood levels of Upwardz leading to higher chances of side effects.
Q. Can I take Upwardz with tramadol?
Yes, Upwardz can be taken with tramadol. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. How safe is it to use Upwardz with paracetamol?
Yes, Upwardz can be taken with paracetamol. It is used by many patients to relieve a headache caused by Upwardz. No drug-drug interactions or any harmful effects have been reported when they are used together.
No, Upwardz is not a nitrate. It belongs to a group of medicines called phosphodiesterase 5 inhibitors used for the treatment of erectile dysfunction.
Q. Is Upwardz a controlled substance?
Upwardz is not a controlled substance. It's a prescription medicine and is available on providing a valid prescription by a doctor.
Q. Is Upwardz a blood thinner?
No, Upwardz is not a blood thinner. It belongs to a group of medicines called phosphodiesterase 5 inhibitors used for the treatment of erectile dysfunction.
Q. Is Upwardz a prescription medicine?
Yes, Upwardz is a prescription medicine. It is available for providing a valid prescription by a doctor.
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