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TRUXOFOL 7.5MG/1MG TABLET

Tablet
MRP: Rs. 50 for 1 strip(s) (28 tablets each)
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Composition for TRUXOFOL

Methotrexate(7.5 mg),Folic Acid(1 mg)

food interaction for TRUXOFOL

alcohol interaction for TRUXOFOL

pregnancy interaction for TRUXOFOL

lactation interaction for TRUXOFOL

food
alcohol
pregnancy
lactation
There is no data available. Please consult doctor before consuming the drug.
Truxofol 7.5mg/1mg tablet may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
Taking Methotrxate with alcohol increases the risk of liver damage.
UNSAFE
Truxofol 7.5mg/1mg tablet is highly unsafe to use during pregnancy.
Human and animal studies have shown significant adverse effects on the foetus. Please consult your doctor.
UNSAFE
Truxofol 7.5mg/1mg tablet is probably unsafe to use during breastfeeding. Please consult your doctor.
UNSAFE

SALT INFORMATION for TRUXOFOL

Methotrexate(7.5 mg)

Uses

Methotrexate is used in the treatment of ovarian cancer, head and neck cancer, cervical cancer, testicular cancer., breast cancer, non-Hodgkin lymphoma (NHL), blood cancer, lung cancer, bone cancer and urinary bladder cancer.
It is also used in rheumatoid arthritis, psoriasis (silvery scaly skin rash) and ectopic pregnancy.

How it works

Methotrexate belongs to a class of drugs known as antimetabolites. Methotrexate is referred to as a cytotoxic, most commonly used to stop the growth of cells in tumors. It acts by decreasing the activity of the immune system by blocking several enzymes involved in the immune system,and affects the growth of cancerous cells.

Common side effects

Pain, Shortness of breath, Persistent cough, Increased sensitivity to light, Acne, Frequent urge to urinate, Liver enzyme increased, Abnormal red blood cell function, Allergic reaction, Drowsiness, Difficulty in speaking, Muscle pain, Joint pain, Blood in urine, Blood vessel inflammation, Blurred vision, Boils, Chills, Convulsion, Coordination disorder, Decreased libido, Diabetes, Diarrhoea, Dizziness, Difficulty in urination, Eye irritation, Fever, Hair loss, Headache, Infertility, Intestinal malabsorption, Decreased red blood cell count, Reduced blood platelets, Decreased white blood cell count, Limb swelling, Loss of appetite, Feeling of discomfort, Black and bloody stools, Metabolic disorder, Mood changes, Rash, Skin damage, Skin inflammation, Skin erosion, Skin flakes, Skin ulcer, Sore throat, Steven-johnsons syndrome, Stomach pain, Vaginal irritation, Vaginal swelling, Vaginal ulcers, Fatigue, Weakness, Softening of bones, Yellow discoloration of skin, Yellow discoloration of eye, Thought disorder, Nausea
Folic Acid(1 mg)

Uses

Folic Acid is used in the treatment of iron deficiency anemia and anemia due to chronic kidney disease.

How it works

Folic acid is a component of the B group of vitamins and is necessary for the normal production and maturation of red blood cells.

Common side effects

Shortness of breath, Itching, Rash, Skin redness

SUBSTITUTES for TRUXOFOL

2 Substitutes
Sorted By
RelevancePrice
  • MEXT F 7.5MG/1MG TABLET
    (28 tablets in strip)
    Wallace Pharmaceuticals Pvt Ltd
    Rs. 2.14/tablet
    Tablet
    Rs. 60
    pay 20% more per tablet
  • MEXT F 7.5MG/1MG TABLET
    (24 tablets in strip)
    Wallace Pharmaceuticals Pvt Ltd
    Rs. 1.89/tablet
    Tablet
    Rs. 45.35
    pay 6% more per tablet

Expert advice for TRUXOFOL

Do not take methotrexate:
  • If you are allergic (hypersensitive) to methotrexate or to any of the other ingredients of this medicines.
  • If you are pregnant, planning to become pregnant or are breastfeeding.
  • If you have severe kidney or liver problems such as fibrosis, cirrhosis and recent hepatitis.
  • If you are alcoholic.
Methotrexate should not be taken with food, as it may interact and reduce its absorption. Do not drive or use any tools or machines, if you feel dizzy, tired, have a headache or get blurred vision after taking methotrexate. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, body aches). Methotrexate is not recommended in children other than in cancer chemotherapy.Immediately consult  your doctor if you have upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes), dry cough, shortness of breath, blood in your urine, or little or no urinating.Use birth control to prevent pregnancy while you are using methotrexate, whether you are a man or a woman. Methotrexate use by either parent may cause birth defects.Continue using condoms for at least 90 days after your treatment ends.Women should continue taking effective form of birth control for at least one cycle of ovulation after the treatment ends.

Frequently asked questions for TRUXOFOL

Methotrexate

Q.Is methotrexate a steroid/ chemotherapy/ disease-modifying antirheumatic drugs (DMARD)/ non-steroidal anti-inflammatory drugs (NSAIDs)?
Methotrexate is not a steroid or non-steroidal anti-inflammatory drugs (NSAIDs). It is a chemotherapy drug used in the treatment of different types of cancer and it is also a disease-modifying antirheumatic drugs (DMARD) used in the treatment of severe rheumatoid arthritis

Q.Is methotrexate safe for psoriasis?
Methotrexate belongs to a class of drugs known as antimetabolites used to treat severe, uncontrolled psoriasis. Methotrexate is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Q.Is methotrexate cell cycle specific?
Yes. Methotrexate's chemotherapeutic effects are cell-cycle specific as it inhibits the DNA synthetic phase, i.e. it inhibits the synthesis of DNA (genetic material) of the cells. Hence in cancer treatment, it kills the cancerous cells and reduces the tumor size

Q.Is methotrexate safe/ How long can I take methotrexate for?
Methotrexate is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Q.Is methotrexate a narcotic/ biologic drug?
No. Methotrexate is not a narcotic drug/ biologic drug

Q.Can I take methotrexate with antibiotics (e.g. amoxicillin, Bactrim)/ ibuprofen/ prednisone/ naproxen/ aspirin/ paracetamol?
No. Methotrexate interacts with antibiotics (e.g. amoxicillin, Bactrim), ibuprofen, prednisone, naproxen, aspirin, paracetamol. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required

Q.Can I take methotrexate with a cold?
Always consult your doctor regarding its use if you have any symptoms of infection such as cold

Q.Does methotrexate cause cancer?
Methotrexate belongs to a class of drugs known as antimetabolites. It is used for the treatment of wide range of cancer and tumors. However it may increase the risk of secondary malignancies such as melanoma and other cancers

Q.Does methotrexate cause weight gain/ weight loss/ fatigue/ diarrhea/ acne/ mood swings/ nausea/ infertility?
Methotrexate may cause side effects such as fatigue, diarrhea, acne, mood swings, nausea, and infertility. But it has no known effect on weight gain/ weight loss

Q.Does methotrexate work and what does methotrexate treat?
Methotrexate belongs to a class of drugs known as antimetabolites. Methotrexate is used for the treatment of wide range of cancers or tumors including acute leukemias (a type of blood cancer), non-Hodgkin's lymphoma (a type of cancer of immune system cells that help the body fight infections), soft-tissue (fat, muscle, nerves, fibrous tissues, blood vessels, or deep skin tissues of the body) and osteogenic sarcomas (bone cancer), and solid tumors (cancers) of the breast, lung, head and neck, bladder, cervical, ovarian, choriocarcinoma and testicular carcinoma. It is also used to treat severe, uncontrolled psoriasis (skin condition where scaly patches were formed due to fast growing cells) and rheumatoid arthritis (inflammatory disorder that typically affects the small joints in hands and feet) only if these have not responded to other frontline treatments.

Folic Acid

Q.Does folic acid contain iron?
Folic acid is a component of the B group of vitamins

Q.Can I take folic acid with iron supplement?
It does not contain iron and can be taken with iron supplement

Q.Does vitamin D have folic acid?
Folic acid is a component of the B group of vitamins and it does not have Vitamin D

Q.Is folic acid good for everyone/skin/health/polycystic ovarian syndrome (PCOS)/hair loss/anemia?
Everyone needs folic acid for good health. It is good for skin, hair, polycystic ovarian syndrome (PCOS) and anemia. However, patients should follow the advice of the doctor regarding the use of folic acid

Q.What is Folvite/ Fol123/ Folvite MB tablet used for?
Folvite/ Fol123/ Folvite MB are the trade names for active drug folic acid. Folvite contains only folic acid which is a component of the B group of vitamins. While Fol123/ Folvite MB, in addition to folic acid also has other forms of vitamin B. In addition folic acid is also used for prevention of folate deficiency caused by some medicines (e.g. phenytoin, phenobarbital and primidone used to treat epilepsy), folate deficiency caused by long-term red blood cell damage or kidney dialysis However, patients should follow the advice of the doctor regarding the dose and duration of use of folic acid

Q.How long can I take folic acid for?
Always follow the instructions of doctor regarding the dosage and duration

Q.Does folic acid have side effects increase weight/acidity?
Folic acid may have rare side effect like acidity, while it has no known effect on weight gain

Q.Can I take folic acid with birth control?
Folic acid supplementation does not affect birth control, and can be taken if you are suffering from anemia due to folic acid deficiency However, always follow the advice of the doctor regarding the dose and duration of use of folic acid

Q.Can I take folic acid with methotrexate/warfarin/calcium/metformin/antibiotics?
Folic acid may interact with medicines such as methotrexate/sulfonamide antibiotics (sulfasalazine, cotrimoxazole etc). It has no known effect if taken with warfarin/calcium/ metformin.

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Content on this page was last updated on 12 May, 2014, by Dr. Varun Gupta (MD Pharmacology)