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Triplus Injection 1
Triplus Injection 2
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Triplus Injection

Tramadol (50mg/ml)
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Product Summary :

Triplus Injection is a pain-relieving medicine used to treat moderate to severe pain, including pain after surgery. It acts on the brain and spinal cord to reduce pain signals. It may cause nausea, dizziness, constipation and sleepiness. It should be administered by a healthcare professional and used for the shortest duration necessary.


Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 13 Nov 2026 | 05:42 PM (IST)
₹21.6 MRP ₹23.448% off 
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General Information

The content is shown in English
Triplus Injection 1
Triplus Injection 2

Product introduction

Triplus Injection is a pain-relieving medicine. It is used to manage persistent, moderate to severe chronic pain that requires continuous, around-the-clock treatment.

Triplus Injection is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms.

The most common side effects of this medicine include nausea, constipation, dry mouth, sleepiness, dizziness, and vomiting. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

Before using it, you should let your doctor know if you have problems with your heart, liver, or kidneys. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

If you are pregnant or breastfeeding, it is important to ask the advice of your doctor before taking this medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.

Uses of Triplus Injection

  • Moderate to severe pain

Benefits of Triplus Injection

Moderate to severe pain
Triplus Injection helps to relieve moderate to severe pain in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.
It is given as an injection by a doctor or nurse and should not be self-administered. The dose and duration will be decided by the doctor depending on the condition you are being treated for. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Triplus Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Triplus
  • Nausea
  • Constipation
  • Sleepiness
  • Dizziness
  • Vomiting

How to use Triplus Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Triplus Injection works

Triplus Injection is an opioid pain reliever that acts on the brain and spinal cord to reduce the perception of pain.

Dosage

Triplus Injection is administered by a healthcare professional as an injection into a vein or muscle, or by infusion, depending on the prescribed treatment. The dose and frequency depend on the severity of pain, your age, medical condition and response to treatment. It is usually administered slowly. The doctor may adjust the dose or interval in patients with kidney or liver problems and older adults.

Quick tips

  • Use only for severe acute pain for not more than 5 days.
  • Prolonged use may result in physical and psychological dependence even at recommended dosages.
  • Avoid driving or using machinery if you feel dizzy after taking Triplus Injection.
  • It is better to take with food to avoid an upset stomach.
  • Your doctor may adjust your dose if you have liver or kidney disease.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Triplus Injection may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Triplus Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

UNSAFE
Triplus Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult a doctor immediately if the baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing problems, or limpness.
Driving

Driving

UNSAFE
Triplus Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Triplus Injection may cause side effects such as drowsiness and blurred vision. If this happens, do not drive.
Kidney

Kidney

CAUTION
Triplus Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Triplus Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Triplus with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Selegiline (Oral Route)

Do not consume Selegiline with Tramadol. If essential, watch out for symptoms such as fever, tremors, diarrhea or agitation. Please consult your doctor.
Life-threatening

Tranylcypromine (Oral Route)

Do not consume Tranylcypromine with Tramadol. If Tranylcypromine is essential, ensure a gap of At least 2 weeks between taking Tranylcypromine and Tramadol. Please consult your doctor.
Life-threatening

Naltrexone (Oral Route)

Do not consume Naltrexone with Tramadol; watch out for symptoms such as breathlessness, increased heart rate, or headache. Naltrexone may reduce efficacy of Tramadol.
Severe

Alprazolam (Oral Route)

If concurrent use is essential, watch out for symptoms of Alprazolam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Alprazolam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Severe

Alprazolam (Injection Route)

If concurrent use is essential, watch out for symptoms of Alprazolam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Alprazolam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.

Frequently asked questions

Triplus Injection is used to treat moderate to severe pain, including pain after surgery. It may be prescribed when other pain-relieving medicines are not suitable or do not provide adequate relief. Triplus Injection acts on opioid receptors in the brain and spinal cord and also affects chemical messengers involved in controlling pain signals. These actions help reduce the sensation of pain.
Triplus Injection is administered by a healthcare professional through an injection into a vein or muscle, or by infusion, depending on your condition and the doctor's instructions. Do not attempt to inject it yourself.
When given by injection, Triplus Injection generally starts relieving pain relatively quickly. The time taken can vary depending on the route of administration and individual response.
Yes. Triplus Injection may cause sleepiness, dizziness or blurred vision. Avoid driving, operating machinery or performing activities that require alertness until its effects have worn off.
Inform your doctor if you take sleeping pills, anxiety medicines, sedatives or other medicines that cause sleepiness. Combining these with Triplus Injection may increase the risk of severe sedation and breathing problems.
Yes. Repeated or prolonged use may lead to tolerance, physical dependence or addiction. It should be used only under medical supervision and for the shortest duration necessary. Do not stop prolonged treatment suddenly without medical advice.
Yes. Triplus Injection may cause seizures, although the risk may be higher with excessive doses or certain interacting medicines. Inform your doctor if you have epilepsy or a history of seizures.

Fact Box

Chemical Class

Phenylpropylamine derivative

Habit Forming

Yes

Therapeutic Class

PAIN ANALGESICS

Action Class

Opioids

References

  1. Schumacher MA, Basbaum AI, Way WL. Opioids Analgesics & Antagonists. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 547.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1384-86.
  3. ScienceDirect. Tramadol. [Accessed 02 Apr. 2019] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
  5. Tramadol [Professional Information]. SunPharma 2025. [Accessed 13 Nov. 2026] (online). Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Mediwill Life Sciences
Address: no. 1/1, m. m. lane, cotton pet, 2nd cross, cottonpete, bengaluru-560053, karnataka, india

Vendor Details

Country of origin: India
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