Side Effects of Tri Zyromet G are Hypoglycemia (low blood sugar level), Nausea, Taste change, Diarrhoea, Stomach pain, Headache, Edema (swelling), Weight gain, Blurred vision, Bone fracture, Respiratory tract infection.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tri-Zyromet G1 Tablet is to be taken with food. Tri-Zyromet G1 Tablet may cause stomach upset if taken empty stomach.
Tri-Zyromet G1 Tablet is a combination of three antidiabetic medicines: Glimepiride, Metformin and Pioglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Pioglitazone is a thiazolidinedione which further increases insulin sensitivity.
Taking pioglitazone with alcohol may affect blood glucose levels in patients with diabetes.
WEIGH RISKS VS BENEFITS
Tri-Zyromet G1 Tablet may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Tri-Zyromet G1 Tablet is probably safe to use during lactation.
Limited human data suggests that the drug does not represent a significant risk to the baby. Monitor the breastfed baby’s blood sugar during treatment with Tri-Zyromet G1 Tablet
Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.
Tri-Zyromet G1 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Tri-Zyromet G1 Tablet may be needed. Please consult your doctor. Use of Tri-Zyromet G1 Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Tri-Zyromet G1 Tablet should be used with caution in patients with liver disease. Dose adjustment of Tri-Zyromet G1 Tablet may be needed. Please consult your doctor. Use of Tri-Zyromet G1 Tablet is not recommended in patients with severe liver disease.