Medicine Overview of Topotec Injection
Fatigue, Nausea, Vomiting, Hair loss, Low blood platelets, Anemia (low number of red blood cells), Infection, Decreased white blood cell count (neutrophils), Fever, Mucosal inflammation, Weakness, Diarrhoea, Decreased white blood cell count, Decreased appetite, Abdominal pain, Constipation.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Topotec 2.5mg Injection is an anti-cancer medication. It is an inhibitor of topoisomerase, an enzyme important for replication of genetic material (DNA) in the cancer cells. Thus it stops the growth and multiplication of cancer cells.
In Depth Information on Topotec Injection
- Before you take topotecan, inform your doctor if have /are being treated for kidney disease.
- If you are undergoing a surgery including dental surgery, do inform your doctor that you are being treated with topotecan.
- Do not drive or operate machinery as topotecan may cause tiredness, drowsiness or weakness.
- Take precautions while using topotecan as it may cause severe diarrhea requiring hospitalization.
- You should get your blood count monitored regularly to check for any signs of serious infections.
- Stop using topetecan and immediately report any pulmonary symptoms indicative of interstitial lung disease (e.g. cough, fever, dyspnoea and/or hypoxia).
- Tell your doctor if you are or planning to become pregnant or are breastfeeding.
Topotec Injection related warnings
Interaction with alcohol is unknown. Please consult your doctor.
WEIGH RISKS VS BENEFITS
Topotec 2.5mg Injection is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Topotec 2.5mg Injection is unsafe to use during lactation.
Data suggests that the drug may cause toxicity to the baby, or the mother is suffering from a condition in which breastfeeding is not advisable.
Do not drive unless you are feeling well.
Topotec 2.5mg Injection can make you feel tired and this may affect your ability to drive.
Topotec 2.5mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Topotec 2.5mg Injection may be needed. Please consult your doctor.
Use of Topotec 2.5mg Injection is not recommended in patients with end-stage kidney disease.
Topotec 2.5mg Injection is safe to use in patients with liver disease. No dose adjustment of Topotec 2.5mg Injection is recommended.
If you miss a dose of Topotec 2.5mg Injection, please consult your doctor.
Frequently asked questions about Topotec Injection
Generally Topotec treatment is for 4 cycles of 21 day each, patient is given Topotec for first 5 days of each cycle
Yes, Topotec may cause temporary hair loss
Yes, Topotec may cause flare reaction
The drug may start its action once the infusion is started, however, the complete effect may be assessed only after completion of 4 cycles
Topotec is a vesicant (irritant)
Yes Topotec is effective if used at prescribed doses for the prescribed duration as advised by your doctor
It is a treatment therapy that includes Topotec with or without combination of other drugs in treatment of cancer (Usually ovarian or lung cancer)
Topotec is either administered orally as a capsule or as an intravenous Infusion in the arm over a period of 30 min.
One of the following vendor pharmacies will deliver Topotec 2.5mg Injection: VRS, KAL, INC, MAM, MAX, NDP, OIP, GHR, BGS, TRP, SBA, ARD, HPC, MBP, GPT, ZEL, 4IT, SRG, AWS, RSS, JIV, NTB, EPS, RPP, NNP, PVP, RDH, EMB, OHM, RHL, SVH, BLS, BTM, STA, DYG, IAD, QTM, PMA, BDN, ANT, BMJ, GBL, DGN, KIS, JBT, GTK, PWN, UBL, JVO, SYN, AYM, TFP, PTI, RSA, TSS, MAP, RJH, SJP, RKS, BAL, ADT, VJS, BHM, HBV, P2P, PEN, DPP, NVL, HSP, NWP, BHS, RPI, FGH, 9T9, AYU, RWP, MDH, KHH, AAR, VDH, AAY, MMS, ZPR, BSN, DPL, SPD, PRN, NAS, DVH, 9MM, CHP, LCC, SVS, HTS, ABP, MPC, RHW, AVS, OLT, HEX, LHA, HNP, TOM, BBS, IPL, DHR, USF, BIO, PLT, HAT, GNC, ZVP, DFP, SAF, SGH, SBL, BLE, SGC, JHC, SHD, EQN, SMN, CLT, EVP, RDR, JVN, SWA, DZY, UMP, NXG, RUS, TNH, HIP, PNT, SDM, MDO, QLF, KMC, DAO, HMP, GTC, GPP, BHP, AMR, AGT, SLN, HGI, MSD, BAP, WHL, PPR, ESY, LMS, JSL, KHC, SCH, WSI, THP, ATP, MAK, HZF, ENP, DHP, SWP, MLC, VNS, ATL, OWP, NVY, SSA, SHC