Tilcef 250mg Tablet

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 02 Feb 2026 | 12:47 PM (IST)

Tilcef 250mg Tablet is an antibiotic medicine used to treat bacterial infections in your body. It is effective in infections of the lungs (e.g., pneumonia), ear, throat, nasal sinus, urinary tract, skin, soft tissues, bones, and joints. It is also used to prevent infections during surgery.

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Tilcef 250mg Tablet

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Same composition

Novacef 250 Tablet

strip of 10 tablets

Cefuroxime (250mg)

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General Information

Contains

Cefuroxime (250mg)

Marketer

Bios Lab

Storage

Store below 30°C

The content is shown in English

Product introduction

Tilcef 250mg Tablet can be taken with or without food. Take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you remember to take it. The dose will depend on what you are being treated for and the severity of your condition. Make sure to complete the full course. It will not work for viral infections such as the flu or the common cold. Using any antibiotic when you do not need it can make it less effective for future infections.

The most common side effects of this medicine include rash, vomiting, nausea, and diarrhea. These are usually mild, but let your doctor know if they bother you or last more than a few days.

Before using it, you should tell your doctor if you are allergic to any antibiotics or have any kidney or liver problems. You should also let your doctor know all other medicines you are taking as they may affect, or be affected by, this medicine. Pregnant and breastfeeding mothers should consult their doctor before using it.

Uses of Tilcef Tablet

Treatment of Bacterial infections

Benefits of Tilcef Tablet

Treatment of Bacterial infections
Tilcef 250mg Tablet is a versatile antibiotic medicine that kills the infection-causing bacteria in your body. This medicine is used to treat many different types of infections, such as those of the lungs (pneumonia), ear, abdomen, urinary tract, bones, joints, skin, and soft tissues. This medicine usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better. Stopping it early may make the infection come back and harder to treat.

Side effects of Tilcef Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tilcef

Rash
Vomiting
Allergic reaction
Nausea
Diarrhea

How to use Tilcef Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tilcef 250mg Tablet may be taken with or without food.

How Tilcef Tablet works

Tilcef 250mg Tablet is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall), which is needed for them to survive.

All substitutes for Tilcef 250mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Your doctor has prescribed Tilcef 250mg Tablet to cure your infection and improve your symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect, but it should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.
Discontinue Tilcef 250mg Tablet and inform your doctor immediately if you get a rash, itchy skin, swelling of the face and mouth, or have difficulty breathing.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Tilcef 250mg Tablet. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Tilcef 250mg Tablet is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.

Breast feeding

CAUTION

Tilcef 250mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Avoid prolonged use of Tilcef 250mg Tablet, since it may have possible effects such as rash and diarrhea.

Driving

CONSULT YOUR DOCTOR

It is not known whether Tilcef 250mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
It may cause dizziness in some patients. Patients should be cautious when driving or operating machinery.

Kidney

CAUTION

Tilcef 250mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

SAFE IF PRESCRIBED

Tilcef 250mg Tablet is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Tilcef with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not consume Cholera Vaccine (Inactivated) two weeks before and at least 10 days after consuming Cefuroxime. Please consult your doctor. Cefuroxime may reduce the efficacy of Cholera Vaccine (Inactivated).

Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Cefuroxime may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine. Cefuroxime may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine.

Moderate

Amikacin (Injection Route)

Your doctor may monitor your kidney function regularly.

Moderate

Mycophenolate mofetil (Oral Route)

Your doctor may monitor the effects of Mycophenolate mofetil along with your overall treatment and adjust the doses as per the observations. Mycophenolate mofetil may increase the rate of release of Cefuroxime in the blood.

Moderate

Kanamycin (Injection Route)

Your doctor may monitor your kidney function regularly.

Frequently asked questions

How long does Tilcef 250mg Tablet take to work?

The amount of time Tilcef 250mg Tablet takes to work depends on the type of infection and response of the patient to the medicine. The antibiotic may start working after you take it but for maximum effect it may require some time. Usually, the symptoms of bacterial infections start to decrease in 48 to 72 hours after starting the medication.

How long should you take Tilcef 250mg Tablet?

The duration of therapy with Tilcef 250mg Tablet depends upon the type of infection. It is usually given for 7 days. It ranges from 5 to 10 days and depends on the response of the infection in the patient. Before starting the medication consult a doctor who will prescribe the exact duration of therapy and follow the instructions as given.

Can Tilcef 250mg Tablet treat UTI?

Yes, Tilcef 250mg Tablet can be used to treat urinary tract infection (UTI). But, it is prescribed only in cases of uncomplicated UTIs for 7 to 10 days. The medication is to be prescribed by the doctor only, self-medication is not advised. The severity of the UTI decides the kind of therapy needed to treat it.

Fact Box

Chemical Class

Intermediate spectrum {Second generation cephalosporins}

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Second-Generation Cephalosporins

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 232.
Cefuroxime [EMC SmpC]. Camberley Surrey: Sandoz Limited; 2025. [Accessed 29 Oct. 2025] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
Cefuroxime Axetil [Prescribing Information]. Roorkee, Uttarakhand: Twenty First Century Pharmaceutical Pvt. Ltd.; 2023. [Accessed 29 Oct. 2025] (online) Available from:
Cefuroxime. Indiana, PA: Remedyrepack INC.; 2025. [Accessed Feb 2 2026] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Bios Lab
Address: Bios Lab 206 , Maruti Nandan Complex, 2/10 Bhaktinagar Station Plot, Rajkot – 360 002 (Gujarat) - India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Tilcef 250mg Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Tilcef Tablet

Benefits of Tilcef Tablet

Side effects of Tilcef Tablet

How to use Tilcef Tablet

How Tilcef Tablet works

All substitutes for Tilcef 250mg Tablet

Cefasyn 250 Tablet

Ceftum 250mg Tablet

Cefakind 250 Tablet

Zocef 250 Tablet

Cetil 250 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Cholera Vaccine (Inactivated) (Oral Route)

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Amikacin (Injection Route)

Mycophenolate mofetil (Oral Route)

Kanamycin (Injection Route)

Frequently asked questions

How long does Tilcef 250mg Tablet take to work?

How long should you take Tilcef 250mg Tablet?

Can Tilcef 250mg Tablet treat UTI?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests