Tignus 50mg Injection

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 25 Nov 2025 | 03:05 PM (IST)

Tignus 50mg Injection is an antibiotic that fights bacteria. It is used to treat severe infections of the body like skin, intra-abdominal infections, and community-acquired bacterial pneumonia. It works by killing the bacteria that cause these problems. But, it will not treat a viral infection.

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required

Cold stored

Stored between 2-8°C

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Tigecycline (50mg)

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General Information

Contains

Tigecycline (50mg)

Marketer

Stenhill Labs

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Tignus 50mg Injection is commonly used to treat critically ill patients admitted to the hospital. This medicine is given by drip or by direct injection into a vein by a doctor or a nurse. The dose will depend on what type of infection you have, where it is in the body, and how serious it is. You should have your injections at the same time each day to get the most benefit and you should keep on taking this medicine for as long as you are prescribed it, even if your symptoms quickly improve. If you stop taking it too early the infection may return or worsen.

Some people may develop side effects like headache, vomiting, nausea, increased liver enzymes, stomach pain, and diarrhea. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or do not go away. It may also cause dizziness, so do not drive or do anything that requires mental focus.

Before starting treatment with this medicine, you should tell your doctor if you are pregnant, breastfeeding, or suffering from any liver problems or if you are allergic to any antibiotic. While using it, you may be advised blood tests to monitor your liver function.

Uses of Tignus Injection

Severe bacterial infections

Benefits of Tignus Injection

Severe bacterial infections
Tignus 50mg Injection works by killing bacteria which can cause serious infections. It is used to treat many different types of bacterial infections such as infections of the lungs (pneumonia), stomach, and skin. It is given by a doctor or nurse into a vein and should not be self-administered. Tignus 50mg Injection usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Tignus Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tignus

Headache
Vomiting
Nausea
Increased liver enzymes
Stomach pain
Diarrhea

How to use Tignus Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Tignus Injection works

Tignus 50mg Injection is an antibiotic. It stops bacterial growth by preventing synthesis of essential proteins required by bacteria to carry out vital functions.

All substitutes for Tignus 50mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Tignus 50mg Injection is an antibiotic that is usually only given in the hospital for serious infections.
Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
It may cause dizziness. Don't drive or do anything that requires mental focus until you know how Tignus 50mg Injection affects you.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Your doctor has prescribed Tignus 50mg Injection to cure your infection and improve symptoms.
It should be taken on an empty stomach.
Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
It may cause dizziness. Don't drive or do anything that requires mental focus until you know how Tignus 50mg Injection affects you.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
It can lower the efficacy of birth control pills. Use an alternative method of contraception ( condom, diaphragm, spermicide) while taking this medication.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Do not take antacids or medicines containing zinc or iron at least 2 hours before or 6 hours after taking Tignus 50mg Injection.
Discontinue Tignus 50mg Injection and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.

Safety advice

Alcohol

SAFE

Consuming alcohol with Tignus 50mg Injection does not usually cause any harmful side effects.

Pregnancy

CONSULT YOUR DOCTOR

Tignus 50mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Tignus 50mg Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Tignus 50mg Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Tignus 50mg Injection is safe to use in patients with kidney disease. No dose adjustment is recommended.

Liver

CAUTION

Tignus 50mg Injection should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Tignus with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Tretinoin (Oral Route)

Do not consume Tretinoin with Tigecycline.

Severe

Isotretinoin (Oral Route)

Do not consume Isotretinoin with Tigecycline.

Severe

Acitretin (Oral Route)

Do not consume Acitretin with Tigecycline.

Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Tigecycline may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine. Tigecycline may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine.

Moderate

Bemiparin (Injection Route)

If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and consult your doctor if you experience them. They may adjust the doses as per the observations.

Frequently asked questions

How long does Tignus 50mg Injection takes to work?

Usually, Tignus 50mg Injection starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.

Can the use of Tignus 50mg Injection cause diarrhea?

Yes, the use of Tignus 50mg Injection can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If diarrhea persists, talk to your doctor about it.

Fact Box

Chemical Class

Tetracyclines

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Bacterial Protein Synthesis Inhibitors- Tetracyclines

Related lab tests

Complete Blood Count

References

MacDougall C, Chambers HF. Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1521-26.
Chambers HF, Deck DH. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidiones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 798.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1339-142.
ScienceDirect. Tigecycline. [Accessed 29 Mar. 2019] (online) Available from:
Tigecycline. Philadelphia, PA: Wyeth Pharmaceuticals Inc.; 2005. [Accessed 29 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Stenhill Labs
Address: Plot No. 463 Industrial Area Phase-1, Panchkula Chandigarh

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Tignus 50mg Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Tignus Injection

Benefits of Tignus Injection

Side effects of Tignus Injection

How to use Tignus Injection

How Tignus Injection works

All substitutes for Tignus 50mg Injection

Tigi 50mg Injection

Zutig 50 Injection

Tiganex 50mg Injection

Tigene Injection

Tigebest 50mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tretinoin (Oral Route)

Isotretinoin (Oral Route)

Acitretin (Oral Route)

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Bemiparin (Injection Route)

Frequently asked questions

How long does Tignus 50mg Injection takes to work?

Can the use of Tignus 50mg Injection cause diarrhea?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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