Themibuprine 100mg Patch
Prescription Required
Product introduction
Themibuprine 100mg Patch is used to treat moderate to severe pain and drug dependence/addiction to opioids. It helps prevent withdrawal symptoms that may be caused due to withdrawal of other opioids.
Your doctor will explain how to use Themibuprine 100mg Patch. Follow the instructions carefully to get the most benefit. The dose and duration will depend on what you are using it for and how well it helps your symptoms. Use it regularly and do not discontinue using it until the doctor tells you it is alright to stop.
The most common side effects of this medicine include constipation, dizziness, drowsiness, headache, and nausea. You may have side effects more often when you start your treatment or when your dose is increased. Usually, the side effects will slowly go away as your body gets used to it. If they are severe or do not go away, you should remove your patch and contact your doctor.
Before using the medicine, you should tell your doctor if you have any other illnesses or disorders. It may also affect, or be affected by some other drugs you are using. Let your doctor know all the other medicines you are taking or using to make sure it is safe for you. Pregnant and breastfeeding women should consult their doctors first before using the medicine.
Uses of Themibuprine Patch
- Opioid (Morphine) dependence
- Moderate to severe pain
Side effects of Themibuprine Patch
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Themibuprine
- Headache
- Back pain
- Drowsiness
- Vomiting
- Insomnia (difficulty in sleeping)
- Dizziness
- Abdominal pain
- Weakness
- Sweating
- Constipation
- Withdrawal syndrome
- Infection
- Vertigo
- Inflammation of the nose
- Chills
- Flu-like symptoms
- Nausea
How to use Themibuprine Patch
Use this medicine in dose and duration as advised by your doctor. Check the label before use. Make sure the skin is clean and dry. Remove the protective liner of the patch. Do not touch the sticky side. With sticky side down, place the patch evenly onto the skin.
How Themibuprine Patch works
Themibuprine 100mg Patch is a opioid partial agonist. It prevents withdrawal symptoms in patients who stop taking opioid drugs by producing similar effects to these drugs. It also provides pain relief by acting on specific receptors in the brain that change how your body feels and responds to pain.
Safety advice
Alcohol
No interaction found/established
Pregnancy
CONSULT YOUR DOCTOR
Themibuprine 100mg Patch may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Themibuprine 100mg Patch is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
No interaction found/established
Kidney
CAUTION
Themibuprine 100mg Patch should be used with caution in patients with severe kidney disease. Dose adjustment of Themibuprine 100mg Patch may be needed. Please consult your doctor.
Liver
CAUTION
Themibuprine 100mg Patch should be used with caution in patients with severe liver disease. Dose adjustment of Themibuprine 100mg Patch may be needed. Please consult your doctor.
Consider the use of an alternate analgesic that may permit more flexibility with the dosing in patients with severe hepatic impairment.
Consider the use of an alternate analgesic that may permit more flexibility with the dosing in patients with severe hepatic impairment.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Themibuprine 100mg Patch should be used as advised by the doctor.
- You should change the patch every 7 days and apply a new patch to a new site.
- Do not expose the patches to a heat source.
- Avoid drinking alcohol or taking other medicines that can cause drowsiness.
- It has a high potential for abuse, misuse, or addiction even at normal doses.
- Discontinue the medicine and inform your doctor if you experience difficulty breathing.
- Do not stop taking Themibuprine 100mg Patch without talking to your doctor first as it may cause a worsening of symptoms.
- Take it at the same time every day to help you remember to take it.
- To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
- Use caution while driving or doing anything that requires concentration as Themibuprine 100mg Patch can cause dizziness and sleepiness.
- Avoid drinking alcohol or taking other medicines that can cause drowsiness.
- Discontinue the medicine and inform your doctor if you experience difficulty breathing.
- Do not stop taking Themibuprine 100mg Patch without talking to your doctor first as it may cause a worsening of symptoms.
- Your doctor may get regular blood tests to check for liver function while taking this medicine.
Fact Box
Chemical Class
Phenanthrenes Derivatives
Habit Forming
.
Therapeutic Class
NEURO CNS
Action Class
Opioids- Partial agonist
Interaction with drugs
Taking Themibuprine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Naltrexone may reduce efficacy of Buprenorphine.
Do not consume Naltrexone with Buprenorphine; watch out for symptoms such as breathlessness, increased heart rate, or headache.
Concurrent use may cause increased sleepliness, slow breathing, and even death.
If concurrent use is essential, watch out for symptoms of Diazepam side effects such as drowsiness,
Concurrent use may cause increased sleepliness, slow breathing, and even death.
If concurrent use is essential, watch out for symptoms of Diazepam side effects such as drowsiness,
Concurrent use may cause increased sleepliness, slow breathing, and even death.
If concurrent use is essential, watch out for symptoms of Alprazolam side effects such as drowsines
Concurrent use may cause increased sleepliness, slow breathing, and even death.
If concurrent use is essential, watch out for symptoms of Diazepam side effects such as drowsiness,
Patient concerns
FAQs
What is Themibuprine 100mg Patch used for?
Themibuprine 100mg Patch is used to relieve severe pain when other pain medicines did not work well enough or cannot be tolerated. This medicine is not used for minor pain or pain that only sometimes occurs. It should not be used to treat pain that you only have once in a while or "as needed". It is also used to treat opioid use disorder.
How to use Themibuprine 100mg Patch?
Themibuprine 100mg Patch should be applied to a clean, dry, rash-free, hairless, or nearly hairless area of skin on the upper chest, back, or arm, or side of the chest. Only use water to clean the area of skin prior to application because other substances (such as soaps, oils, or gels) may alter the absorption of the drug. Discard used patches carefully and out of reach of children or pets. Keep in mind that the skin is not the same everywhere on your body. Be sure to place the patch according to instructions from your doctor.
What precautions are to be taken while using Themibuprine 100mg Patch?
Do not use the skin patch if it has been cut or damaged. Never wear more than 1 patch at a time unless your doctor has told you to. Do not apply the patch to parts of the body that is irritated, broken, cut, or damaged. Do not wear the skin patch on a part of your body where your child could reach or remove the patch from your skin. Avoid allowing children to watch you put on a skin patch. Never tell a child that this skin patch is a "bandage."
What should I avoid while using Themibuprine 100mg Patch?
Avoid sources of heat while wearing the patch. Do not use a heating pad or electric blanket, tanning bed, or sauna. Avoid sunlight, hot bath water, and vigorous activity. Heat can increase the amount of the medicine you absorb through your skin and may cause an overdose or death.
Can I use one patch over another for better effect?
If you’re using more than one patch at a time, never place one patch on top of another. The entire sticky side needs to be in direct contact with your skin. It is advisable to always consult your doctor in case you have any doubts regarding the usage of this medicine.
I am not able to stick Themibuprine 100mg Patch onto my skin, can I use tape to stick?
If in case you are unable to stick the patch onto your skin do not use any dressing or tape. Talk to your doctor or pharmacist for advice.
Can I take bath or shower while using Themibuprine 100mg Patch?
Yes, you can have showers and even go swimming while using Themibuprine 100mg Patch but not for a long period of time. Check the patch is still on properly afterward and dry the area around the patch carefully. If your patch is missing, put another patch on a different part of your body and put the old patch back in the packet it came in. Use it as per your doctor's advice.
I feel dizzy when I get up from a sitting position or when I walk down the stairs. Is it due to Themibuprine 100mg Patch?
This medicine may cause a severe lowering of blood pressure, or a sudden drop in blood pressure when going from sitting to standing, especially if you are taking medications for high blood pressure. Talk to your doctor who might change your dosage.
When to consult the doctor?
Seek immediate medical help if you have shallow breathing, chest pain, fast heart rate, seizure, a light-headed feeling (like you might pass out), blisters, swelling, or severe irritation where the patch was worn, nausea, vomiting, loss of appetite or liver problems like upper stomach pain, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Can I use Themibuprine 100mg Patch during pregnancy?
If you use Themibuprine 100mg Patch while you are pregnant, your baby could become dependent on the medicine. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.
Can I use Themibuprine 100mg Patch while breastfeeding?
Themibuprine 100mg Patch can pass into breast milk and may cause breathing problems or at times or life-threatening problems in a breastfeeding baby. Ask your doctor in detail about all the risks.
How to safely store Themibuprine 100mg Patch?
As with most medications, Themibuprine 100mg Patch should be stored at room temperature. Store it in a secure location where it will not be exposed to excessive heat, moisture or direct sunlight. Keep it out of reach of children. Make sure that any leftover portion is disposed of safely.
Is Themibuprine 100mg Patch an opiate/ opiate blocker/ controlled substance/ pain killer/ addictive?
Themibuprine 100mg Patch belongs to a class of medications called opioid partial agonist-antagonists, which is used to relieve pain. It is a controlled substance and an addictive drug. Consult your doctor for alternate drug if you experience addiction
Does Themibuprine 100mg Patch block opiates?
Yes. Themibuprine 100mg Patch block opiates
Can Themibuprine 100mg Patch cause depression?
Themibuprine 100mg Patch is not known to cause depression. If you experience such side effects, please consult your doctor.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Schumacher MA, Basbaum AI, Way WL. Opioids Analgesics & Antagonists. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 546-47.
- Yaksh TL, WallaceIn MS. Opioids, Analgesia, and Pain Management. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 510.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 165-67.
- Drugs.com. Buprenorphine. [Accessed 02 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
Marketer details
Name: Themis Medicare Ltd
Address: 11/12, Udyog Nagar, S. V. Road, Goregaon (W), Mumbai- 400104.
Country of origin: India
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