Tenfoclear 300mg Tablet

Reviewed By Dr. Mekhala Chandra, MD, MBBS

Last updated on 17 Dec 2025 | 04:35 PM (IST)

Tenfoclear 300mg Tablet is used in the treatment of chronic hepatitis B virus (HBV) infection. It is also used to treat HIV infection in combination with other anti-HIV medicines. It prevents the multiplication of viruses in human cells. This stops the virus from producing new viruses and clears up your infection.

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₹1274 MRP ₹1394.089% off

Tenfoclear 300mg Tablet is currently sold out

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TenoHEP Tablet

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Tenfoclear 300mg Tablet

bottle of 30 tablets

₹1274

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Same composition

TenoHEP Tablet

bottle of 30 tablets

Tenofovir disoproxil fumarate (300mg)

by Zydus Cadila

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General Information

Contains

Tenofovir disoproxil fumarate (300mg)

Marketer

Abbott

Storage

Store below 30°C

The content is shown in English

Product introduction

Tenfoclear 300mg Tablet is not a cure for HIV/AIDS and only helps to decrease the amount of HIV in your body. This helps to lower your risk of getting HIV-related complications and improves your lifespan. It may also be used to prevent HIV infection in some people at high risk. This medicine may be taken with or without food. It is used in combination with other anti-HIV medicines. Taking these medicines regularly at the right time greatly increases their effectiveness and reduces the chances of HIV becoming resistant to them. It is important not to miss doses and to keep taking them until your doctor tells you it is safe to stop.

Common side effects of this medicine include nausea, vomiting, diarrhea, flatulence, trouble sleeping, headache, and rash. These are usually not serious but inform your doctor if they bother you or will not go away. It can also increase the risk of bone loss (osteoporosis) if you take it for a long time. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor. Some people may put on weight while taking medicines to treat HIV/AIDS.

Before taking it, tell your doctor if you have any liver or kidney disease or bone problems. While taking it, you may need regular blood tests to check your blood counts, liver function, and kidney function. Since this medicine may cause dizziness or sleepiness, do not drive until you know how it affects you. Pregnant or breastfeeding mothers should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes, if you are HIV positive. Talk to your doctor about safe ways like condoms to prevent HIV transmission during sex.

Uses of Tenfoclear Tablet

Benefits of Tenfoclear Tablet

Treatment of HIV infection
Tenfoclear 300mg Tablet, when used in combination with other anti-HIV medicines, prevents the HIV virus from multiplying in your body. It helps control the infection and makes your immune system work better. This lowers your chances of getting complications such as new infections and improves your quality of life. This medicine is always taken in combination with other antiretroviral medicines.

It is not a cure of HIV or AIDS and should not be used to prevent HIV after accidental exposure to a risk. It is important that you take this medicine as prescribed, following the dosage recommended by your doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of your combination of medicines and reduces the chances of your HIV infection becoming resistant to antiretroviral medicines. However, taking this medicine will not prevent you from passing HIV to other people.

Side effects of Tenfoclear Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tenfoclear

Diarrhea
Nausea
Rash
Weakness
Vomiting
Fatigue
Abdominal pain
Increased transaminase level in blood
Decreased phosphate level in blood
Pain
Dizziness
Depression
Insomnia (difficulty in sleeping)
Fever
Itching

How to use Tenfoclear Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tenfoclear 300mg Tablet may be taken with or without food.

How Tenfoclear Tablet works

Tenfoclear 300mg Tablet is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

All substitutes for Tenfoclear 300mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

You have been prescribed Tenfoclear 300mg Tablet for the treatment of chronic hepatitis B virus (HBV) infection.
In combination with other medicines, it is used for the treatment of HIV infections.
Take it with food, as this increases the absorption of the medicine into the body.
Tenfoclear 300mg Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
You may still develop infections or other illnesses associated with viral infection while taking this medication.
You can also pass on HIV or HBV to others. Don't share needles or personal items that can have blood or body fluids on them.
During treatment and for at least six months after stopping this medicine, regular blood tests are needed to monitor your liver function, level of hepatitis B virus and blood cells in your blood.
You have been prescribed Tenfoclear 300mg Tablet for the treatment of chronic hepatitis B virus (HBV) infection.
In combination with other medicines, it is used for the treatment of HIV infections.
Take it with food, as this increases the absorption of the medicine into the body.
Tenfoclear 300mg Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
You may still develop infections or other illnesses associated with viral infection while taking this medication.
You can also pass on HIV or HBV to others. Don't share needles or personal items that can have blood or body fluids on them.
During treatment and for at least six months after stopping this medicine, regular blood tests are needed to monitor your liver function, level of hepatitis B virus and blood cells in your blood.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Tenfoclear 300mg Tablet. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Tenfoclear 300mg Tablet is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.

Breast feeding

SAFE IF PRESCRIBED

Tenfoclear 300mg Tablet may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving

UNSAFE

Tenfoclear 300mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Tenfoclear 300mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

SAFE IF PRESCRIBED

Tenfoclear 300mg Tablet is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Tenfoclear with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Acyclovir (Oral Route)

Do not consume Tenofovir disoproxil fumarate with Acyclovir. If concurrent use is essential, your doctor may monitor your kidney function closely.

Severe

Acyclovir (Injection Route)

Do not consume Tenofovir disoproxil fumarate with Acyclovir. If concurrent use is essential, your doctor may monitor your kidney function closely.

Severe

Amikacin (Injection Route)

Do not consume Tenofovir disoproxil fumarate with Amikacin. If concurrent use is essential, your doctor may monitor your kidney function closely.

Severe

Amphotericin B (Injection Route)

Do not consume Tenofovir disoproxil fumarate with Amphotericin B. If concurrent use is essential, your doctor may monitor your kidney function closely.

Severe

Amphotericin B (Vaginal Route)

Do not consume Tenofovir disoproxil fumarate with Amphotericin B. If concurrent use is essential, your doctor may monitor your kidney function closely.

Frequently asked questions

Does Tenfoclear 300mg Tablet prevent passing of HIV-1 and HBV to others?

In case of HIV-1 infection, Tenfoclear 300mg Tablet may reduce the risk of passing the virus to others, but the chances of infecting others still persist. However, in case of HBV infection, Tenfoclear 300mg Tablet has not proven to reduce risk of transferring the virus to others. Therefore, the patients of both HIV-1 infection and HBV infection should practice safe sex and should not share dirty needles.

Is Tenfoclear 300mg Tablet safe?

Tenfoclear 300mg Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

How should I take Tenfoclear 300mg Tablet?

You should take Tenfoclear 300mg Tablet in the dose and duration advised by your doctor. Tenfoclear 300mg Tablet works best when taken with meals or just afterwards. However, taking it without food does not reduce its effectiveness. If you have any doubts, consult your doctor.

For how long do I need to take Tenfoclear 300mg Tablet for HBV infection?

Duration of treatment will depend on the severity of HBV infection. You will need to take periodic blood tests to keep a check on the viral load and number of T cells. Your doctor will then decide the duration of the medicine accordingly. In some cases, treatment is required life long.

I vomited after taking Tenfoclear 300mg Tablet. What should I do?

Take another tablet of Tenfoclear 300mg Tablet if you vomit within 1 hour of taking it. If you vomit after more than an hour of taking Tenfoclear 300mg Tablet, then you need not take another tablet. Consult your doctor if you have vomiting every time you take Tenfoclear 300mg Tablet or if the vomiting persists for a longer duration.

What should I do if I forget to take Tenfoclear 300mg Tablet?

If you forget to take Tenfoclear 300mg Tablet within 12 hours of the time you usually take it, you should take Tenfoclear 300mg Tablet with food as soon as possible and resume the normal dosing schedule. If you miss a dose of Tenfoclear 300mg Tablet by more than 12 hours and it is almost time for the next dose, you should not take the missed dose and simply resume the usual dosing schedule.

Fact Box

Chemical Class

6- aminopurines

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Nucleoside/Nucleotide Reverse Transcriptase Inhibitors (NRTIs)

Related lab tests

HIV 1 & 2, Ab Western Blot

HIV 1 And 2 Antibody - Chromatography

HIV 1 And 2 Antibody - ELISA

Hepatitis B (Core) IgM Antibody

Hepatitis B s (Surface) Antigen

Hepatitis C Virus Total Antibody

References

Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 859-60.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1327-28.
Tenofovir disoproxil fumarate. Foster City, CA: Gilead Sciences, Inc; 2001 [revised Jan. 2012]. [Accessed 31 Mar. 2019] (online) Available from:
Tenofovir disoproxil. Limassol, Cyprus: Remedica Ltd.; 2018. [Accessed 24 Jan. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 31 Mar. 2019] (online) Available from:
CiplaMed. Tenofovir Disoproxil Fumarate [Prescriing Informataion]. [Accessed 07 Aug. 2023]. (online) Available from:
Tenofovir disoproxil fumarate [Prescribing Inforamtion]. Indiana, PA: Remedy Repack, Inc.; 2018. [Accessed 07 Aug. 2023]. (online) Available from:

User feedback

Patients taking Tenfoclear 300mg Tablet

Once A Day

100%

What are you using Tenfoclear Tablet for?

Chronic hepatitis B virus (HBV) infection

91%

Others

How much was the improvement?

Average

52%

Poor

36%

Excellent

12%

What were the side-effects while using Tenfoclear 300mg Tablet?

No Side Effect

67%

Headache

33%

How do you take Tenfoclear Tablet?

With or without food

50%

With food

33%

Empty stomach

17%

Please rate Tenfoclear 300mg Tablet on price

Average

50%

Not Expensive

33%

Expensive

17%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Abbott
Address: 16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Tenfoclear 300mg Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Tenfoclear Tablet

Benefits of Tenfoclear Tablet

Side effects of Tenfoclear Tablet

How to use Tenfoclear Tablet

How Tenfoclear Tablet works

All substitutes for Tenfoclear 300mg Tablet

Tenvir Tablet

Reviro 300mg Tablet

Valten 300mg Tablet

TenoHEP Tablet

Teravir Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Acyclovir (Oral Route)

Acyclovir (Injection Route)

Amikacin (Injection Route)

Amphotericin B (Injection Route)

Amphotericin B (Vaginal Route)

Frequently asked questions

Does Tenfoclear 300mg Tablet prevent passing of HIV-1 and HBV to others?

Is Tenfoclear 300mg Tablet safe?

How should I take Tenfoclear 300mg Tablet?

For how long do I need to take Tenfoclear 300mg Tablet for HBV infection?

I vomited after taking Tenfoclear 300mg Tablet. What should I do?

What should I do if I forget to take Tenfoclear 300mg Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

HIV 1 & 2, Ab Western Blot

HIV 1 And 2 Antibody - Chromatography

HIV 1 And 2 Antibody - ELISA

Hepatitis B (Core) IgM Antibody

Hepatitis B s (Surface) Antigen

Hepatitis C Virus Total Antibody

References

User feedback

Patients taking Tenfoclear 300mg Tablet

What are you using Tenfoclear Tablet for?

How much was the improvement?

What were the side-effects while using Tenfoclear 300mg Tablet?

How do you take Tenfoclear Tablet?

Please rate Tenfoclear 300mg Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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