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MD (Pharmacology), MBBS
Last updated:
19 Nov 2019 | 06:23 PM (IST)
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Takfa 0.5 Capsule


Overview

Introduction

Takfa 0.5 Capsule is a medicine known as an immunosuppressant. It is used along with other medicines to prevent your body rejecting a new organ (such as liver, kidney or heart) after transplant. It works by weakening your body’s immune system, so it does not attack the new organ.

Takfa 0.5 Capsule is used with other medicines to prevent rejection. The amount you take and how often you take it depends on the type of transplant you have, your body weight and what other medicines you are taking. Follow your doctor’s instructions carefully. You should take it on an empty stomach, at least one hour before or two hours after a meal. Take this medicine regularly to get the most benefit and keep taking it, even if you feel well. If you stop taking it, you may increase the chances of rejecting your transplanted organ.

Takfa 0.5 Capsule has many potential side effects. It can cause or worsen diabetes and kidney and liver problems. These need urgent medical attention. Other common side effects include nausea, stomach pain, diarrhea and difficulty sleeping. If these or other side effects do not go away or get worse, tell your doctor. Because it lowers your immune system, you may also catch more infections than usual.

Before taking this medicine, tell your doctor if you have kidney, liver or heart problems, diabetes or high blood pressure. Also let your doctor know what other medications you are taking, especially for infections, pain and arthritis. These and others may affect, or be affected by, this medicine. You should limit your exposure to the sun and UV (ultraviolet) light while taking it because immunosuppressants could increase your risk of skin cancer.

Both men and women using this medicine should use effective birth control to prevent pregnancy. This medicine is not normally recommended during pregnancy or while breastfeeding unless it is clearly needed. Before and during treatment you will need frequent medical tests to monitor your progress, and your blood pressure will need to be checked often.

Side effects of Takfa Capsule

Common
  • Diarrhea
  • Increased glucose level in blood
  • Increased thirst
  • Kidney damage
  • Liver damage
  • Nausea
  • Stomach pain
  • Insomnia (difficulty in sleeping)

How to use Takfa Capsule

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Takfa 0.5 Capsule is to be taken empty stomach.

How Takfa Capsule works

Takfa 0.5 Capsule is an immunosuppressant. It works by suppressing your body’s immune response following transplant of an organ (eg. liver, kidney, heart). This helps your body to accept the new organ as if it were your own.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Takfa 0.5 Capsule.
Pregnancy
CONSULT YOUR DOCTOR
Takfa 0.5 Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Takfa 0.5 Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Takfa 0.5 Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Takfa 0.5 Capsule should be used with caution in patients with kidney disease. Dose adjustment of Takfa 0.5 Capsule may be needed. Please consult your doctor.
Liver
CAUTION
Takfa 0.5 Capsule should be used with caution in patients with liver disease. Dose adjustment of Takfa 0.5 Capsule may be needed. Please consult your doctor.

What if you forget to take Takfa Capsule?

If you miss a dose of Takfa 0.5 Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Takfa 0.5 Capsule
₹22.88/Capsule
Pangraf 0.5 Capsule
Panacea Biotec Ltd
₹22.47/Capsule
save 2%
Vingraf 0.5 Capsule
Emcure Pharmaceuticals Ltd
₹19.79/Capsule
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₹24.22/Capsule
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Prograf 0.5mg Capsule
Astellas Pharma Inc
₹22.47/Capsule
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Quick Tips

  • Takfa 0.5 Capsule is used to prevent organ rejection in transplant patients.
  • It may take 3 to 4 months for the medication to work. Keep taking it as prescribed.
  • Your doctor may get regular blood tests done to check the levels of blood cells in your blood. Inform your doctor if you experience unexplained bruising or bleeding, sore throat, mouth ulcers, fever, or general illness. 
  • Your doctor may monitor your kidney function regularly. Drink 8 to 10 glasses of water per day to help with your kidney function.
  • Do not stop taking Takfa 0.5 Capsule without talking to your doctor first.

Interaction with Drugs

Taking Takfa with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Rotasiil, Rotarix, RotaTeq
LIFE-THREATENING
LIFE-THREATENING
Brand(s): Abhay M, Measles, M-Vac
LIFE-THREATENING
Brand(s): Rubella
LIFE-THREATENING

Patient Concerns

arrow
I am having dry eyes so what' drops to put
Dr. Pushkar Mani
Diabetes Specialist
REFRESH TEARS 0.5% 1 drop in both eye ,
Difficulty in excretory, and rejection of stool.
Dr. Aanchal Maheshwari
Ayurveda
take triphala churan 1 spoon at night wioth abhyarishtam 20 ml mixed with water
arrow
Do you have any questions related to Takfa 0.5 Capsule ?

User Feedback


FAQs

Q. Who should not take Takfa?

Patients who are allergic to it or have a weak immune system, high blood pressure and kidney failure should avoid Takfa. This medicine should also be avoided in pregnant or breast-feeding women, and in people who plan to receive any live vaccines (e.g. MMR vaccine). It should also be avoided in patients who have an increased risk of skin cancer.

Q. What should I tell my doctor before taking Takfa?

Inform your doctor if you are pregnant, have allergies, long-term infection, high blood sugar, or high blood pressure. You should also inform your doctor if you have high blood potassium levels or a weakened immune system. Make your doctor aware in case you have a history of any medication, have recently received or are scheduled to receive a live vaccine.

Q. Which vaccines should not be taken while taking Takfa?

You should avoid taking any live vaccines while taking Takfa. These may include vaccinations for measles, mumps, rubella, BCG (TB vaccine), yellow fever, chicken pox and typhoid. You should also avoid taking polio drops (by mouth) or flu vaccine (through nose).

Q. Is Takfa an antibiotic?

Yes, Takfa is a type of antibiotic which belongs to a group called macrolides. It is mostly used after organ transplantation. This medicine’s immune-suppressing property helps prevent organ rejection after kidney, heart, or liver transplant.

Q. What should I be aware of before I start taking Takfa?

As this medicine suppresses the immune system, hence there is always an increased risk of infection. Moreover, Takfa can in some cases increase the risk of some kind of cancers like skin and lymph gland cancer (lymphoma). It can lower the ability of your immune system to fight infections. Consult your doctor before you start taking this medication and in case you notice any symptoms of infections like fever, sweats or chills, cough or flu-like symptoms, muscle aches, warm, red, or painful areas on your skin.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1822.
  2. Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 972.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1305-309.
  4. Tacrolimus monohydrate. Camberley, Surrey: Sandoz Limited; 2010 [revised 27 Mar. 2017]. [Accessed 23 Jan. 2019] (online) Available from:External Link
  5. Drugs.com.Tacrolimus. [Accessed 06 Apr. 2019] (online) Available from:External Link
  6. Tacrolimus. Princeton, New Jersey: Sandoz Inc; 2009. [Accessed 06 Apr. 2019] (online) Available from:External Link
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed 06 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
A licensed pharmacy from your nearest location will deliver Takfa 0.5 Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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