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Composition for SYBIL


food interaction for SYBIL

alcohol interaction for SYBIL

pregnancy interaction for SYBIL

lactation interaction for SYBIL

It can be taken with or without food, but it is better to take Sybil 375mg tablet at a fixed time.
Interaction with alcohol is unknown. Please consult your doctor.
Sybil 375mg tablet is probably safe to use during pregnancy.
Either animal studies have shown no adverse effect on the fetus, but there is no human studies or animal studies have shown an adverse effect that was not confirmed in human studies. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.




Sybil 375mg tablet is used in the treatment of bacterial infections of the skin, abdominal area and female reproductive organs.

How it works

Sybil 375mg tablet is a combination of two antibiotics of the penicillin class, ampicillin and sulbactam. Ampicillin works by inhibiting the proteins that help in the synthesis of bacterial cell wall (outer coating of bacteria) thus killing it. However, some bacteria produce an enzyme called as beta-lactamase that destroys the ampicillin. Sulbactam inhibits the enzyme and thus protects ampicillin. This results in increased anti-bacterial action against those bacteria.

Common side effects

Fungal infection, Jaundice, Convulsion, Flatulence, Altered laboratory test values, Injection site pain, Vomiting, Facial swelling, Bleeding, Chest pain, Blood clot in the legs, Rash, Difficulty in urination, Swelling, Itching, Nausea, Skin redness, Hepatitis (viral infection of liver), Abdominal pain, Headache, Sore throat, Diarrhoea, Fatigue


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Expert advice for SYBIL

  • Sultamicillin is given as a drip (intravenous infusion) or as an injection directly into a vein or into a muscle. It is made up by the doctor, or nurse using water for injections or a suitable infusion fluid.
  • Do not take sultamicillin if you are allergic to it or to any other content in the medicine.
  • Do not take sultamicillin if you have liver disease or cholestatic jaundice; or viral infections.
  • Avoid using sultamicillin if you are pregnant or planning to become pregnant or breast-feeding.

Frequently asked questions for SYBIL


Q.Is sultamicillin an antibiotic/sulfa drug?
Sultamicillin is an antibiotic drug. It is not a sulfa drug.
Q.Is available or sold over the counter?
No. Sultamicillin is a prescription drug. It is not available or sold over the counter.
Q.What is sultamicillin used for?
Sultamicillin is used for the treatment of bacterial infections of the abdomen, skin and female genital tract. It is not indicated for the treatment of cough, cold or throat infections.
Q.Is sultamicillin safe?
Sultamicillin is relatively safe if used as recommended. In case of any side-effects, consult your doctor.


Content on this page was last updated on 21 July, 2016, by Dr. Varun Gupta (MD Pharmacology)