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Composition for SUMITREX

Sumatriptan(50 mg)

food interaction for SUMITREX

alcohol interaction for SUMITREX

pregnancy interaction for SUMITREX

lactation interaction for SUMITREX

It can be taken with or without food, but it is better to take Sumitrex 50mg tablet at a fixed time.
Interaction with alcohol is unknown. Please consult your doctor.
Sumitrex 50mg tablet may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Sumitrex 50mg tablet is probably safe to use during breastfeeding. Please consult your doctor.


Sumatriptan(50 mg)


Sumitrex 50mg tablet is used in the treatment of acute migraine attacks with or without aura (symptoms shortly before headache). The symptoms of migraine may be caused by a temporary widening of blood vessels in the head.

How it works

Sumitrex 50mg tablet belongs to a class of medications called selective serotonin receptor agonists. It works by narrowing blood vessels in the head, stopping pain signals from being sent to the brain, and blocking the release of certain natural substances that cause pain, nausea, and other symptoms of migraine.

Common side effects

Nausea, Numbness, Burning sensation, Throat tightness, Chest tightness, Disorientation (alteration of mental status), Dizziness, Drowsiness, Shortness of breath, Fatigue, Increased blood pressure, Muscle pain, Sensation of heaviness, Sensory distrubance, Tingling sensation, Sleepiness, Pricking sensation, Vomiting, Cold sensation, Warm sensation, Weakness


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Expert advice for SUMITREX

Take sumatriptan as soon as your headache starts. Do not drive because you may feel sleepy or dizzy while being treated with sumatriptan.
  • If your symptoms do not improve after you take sumitriptan, do not take a second tablet without calling your doctor.
  • Limit alcoholic beverages.
Do not start or continue the sumatriptan tablets and consult your doctor:
  • If you have intolerance to some sugars because this medicine contains lactose (a type of sugar).
  • If you have a kidney or liver problem, or epilepsy.
  • If you are considered to have risk factors for developing heart disease such as a family history of heart disease, diabetes, high blood cholesterol, overweight.
  • If you have symptoms of heart disease, such as chest pains or a feeling of pressure in the chest, shortness of breath, or a history of high blood pressure, heart attack, stroke, high cholesterol, diabetes, or smoking.
  • If you use medicines belonging to the group known as selective serotonin reuptake inhibitors (SSRI).
  • If you are smoking regularly or you are a man over 40 years old or a postmenopausal woman.

Frequently asked questions for SUMITREX


Q. Is sumatriptan safe/addictive/controlled substance?
Sumatriptan is relatively safe if used at prescribed doses for the prescribed duration as advised by your doctor. It is not addictive. It is not a controlled substance.
Q. Is sumatriptan a blood thinner or beta blocker or anti-inflammatory/ NSAIDs?
No, sumatriptan is not a blood thinner or beta blocker or anti-inflammatory/NSAIDs.
Q. Is sumatriptan useful for routine headache or sinus headache / tension headache/ hangover?
No, sumatriptan is not useful for routine headache or sinus headache or tension headache or hangover. It is used in the treatment of acute migraine attacks.
Q. Is sumatriptan available over the counter?
No, sumatriptan is not available without a prescription.
Q. Can I take sumatriptan with acetaminophen (paracetamol), aspirin, diclofenac, or penicillin?
Yes, you can take sumatriptan with acetaminophen (paracetamol), aspirin, diclofenac, or penicillin. Please follow the advice of the doctor regarding their simultaneous use.
Q. Can I take Excedrin (acetaminophen, aspirin, and caffeine) with Imitrex (sumatriptan) for migraine?
There is no evidence of any interaction between Excedrin and Imitrex. But please follow the advice of the doctor regarding their simultaneous use.
Q. Can I take sumatriptan with Advil (ibuprofen), Nyquil (, dextromethorphan, doxylamine, and pseudoephedrine), Tylenol (paracetamol), Sudafed (pseudoephedrine), or Vicodin (acetaminophen and hydrocodone)/ aspirin/ diclofenac/ penicillin?
Yes, you may take sumatriptan with Advil, Nyquil, Tylenol, Sudafed, Vicodin, aspirin, diclofenac, or penicillin. Please consult your doctor before use.
Q. Does sumatriptan cause hair loss, weight gain, or joint pain, rebound headache?
Overdose of sumatriptan may cause hair loss, but it is not known to cause weight gain, or joint pain or rebound headache.
Q. Does sumatriptan affect blood pressure?
Sumatriptan may cause transient increases in blood pressure especially in patients with uncontrolled high blood pressure. Consult your doctor before use.
Q. Does sumatriptan affect birth control?
Sumatriptan is not reported to affect birth control. However, consult your doctor for use.


Content on this page was last updated on 06 November, 2014, by Dr. Varun Gupta (MD Pharmacology)