Author Details
Written By
PhD (Pharmacology), PGDPRA
Reviewed By
MD Pharmacology, MBBS
Last updated
21 Dec 2023 | 03:10 PM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Solonex DT Tablet

Prescription Required
SALT COMPOSITION
Storage
Store below 30°C
arrow
arrow

Product introduction

Solonex DT Tablet is an antibiotic used for the treatment and prevention of tuberculosis (TB) and inactive (latent) TB (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body). It works by killing the bacteria that cause tuberculosis.

Solonex DT Tablet should be used in the dose and duration as advised by your doctor. It is to be taken on an empty stomach. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and increase the side effects too. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned.

Some common side effects of this medicine include tingling and numbness of feet and hand (peripheral neuropathy). Inform your doctor if you notice signs of jaundice, i.e., yellowing of eyes or skin, dark urine, stomach pain, or joint pain. You may also develop hepatitis (viral infection of the liver) or increased liver enzymes as side effects of this medicine. Please consult your doctor, as these side effects require medical attention and need dose modification.

Your doctor may monitor your liver function while on treatment with this medicine. Avoid drinking alcohol as this may have additional adverse effects on the liver. Pregnant or breastfeeding women should consult their doctor before using this medicine.

Uses of Solonex Tablet DT

Benefits of Solonex Tablet DT

In Tuberculosis (TB)

Solonex DT Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It kills and stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Side effects of Solonex Tablet DT

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Solonex

  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Hepatitis (viral infection of liver)
  • Skin rash
  • Lethargy
  • Increased liver enzymes

How to use Solonex Tablet DT

Take this medicine in the dose and duration as advised by your doctor. Dissolve it in a glass of water before taking it. Solonex DT Tablet is to be taken empty stomach.
Avoid Solonex DT Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Solonex Tablet DT works

Solonex DT Tablet is an antibiotic. It works by killing the bacteria that causes tuberculosis.

Safety advice

Alcohol
UNSAFE
Consuming alcohol while taking Solonex DT Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
Solonex DT Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Solonex DT Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Solonex DT Tablet may cause side effects which could affect your ability to drive.
Solonex DT Tablet can cause fits, mental health problems and optic neuritis (inflammation of the optic nerve that may cause loss of vision.) This may affect your driving ability.
Kidney
SAFE IF PRESCRIBED
Solonex DT Tablet is safe to use in patients with kidney disease. No dose adjustment of Solonex DT Tablet is recommended.
However, talk to your doctor if you have any underlying kidney disease.
Liver
CAUTION
Solonex DT Tablet should be used with caution in patients with liver disease. Dose adjustment of Solonex DT Tablet may be needed. Please consult your doctor.
Use of Solonex DT Tablet is not recommended in patients with severe liver disease.

What if you forget to take Solonex Tablet DT?

If you miss a dose of Solonex DT Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Your doctor has prescribed Solonex DT Tablet to cure your infection and improve symptoms.
  • It is best taken on an empty stomach.
  • You must also take a vitamin B6 supplement while on Solonex DT Tablet.
  • Tell your doctor immediately if you experience vision changes, loss of appetite, tiredness, stomach pain, nausea or vomiting, yellow skin or eyes or dark-colored urine.

Fact Box

Chemical Class
Nicotinic acid derivatives
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Mycolic acid inhibitors- INH

Interaction with drugs

Taking Solonex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Eurolam, Alwel, Tenzo
Serious
Brand(s): Antep, C Lep, Ametol
Serious
Brand(s): Equblam, Raipox, Equiliser
Serious
Brand(s): Risure
Serious

Patient concerns

arrow
Sir,I'm a tb patient ,doctor give me medicine,but i don't know how i take this medicine ,before meal or after meal please help me This is my medicine Solonex 300 mg R cin 600mg Pyzina 1500mg combutol 1000mg Pyridoxin 40mg
Dr. Pushkar Mani
Physician
That u have to ask ur and also u visit dots centre for tuberculosis tratment
My 7 months child diagnosed with woofing cough.Doctor prescribed Solonex DT half tab for 30 days Health Ok drops 2.5 ml at morning Montemac L at evening Is this prescription is good for him.
Dr. Gopal Bansilal Samdani
Paediatrics
Please share contents of medicine you are takingPlease share the blood reports you have done which suggest this diagnosis.
arrow

User feedback


FAQs

Q. Is Solonex DT Tablet an antibiotic?

Solonex DT Tablet is an antibiotic used in the prevention and treatment of tuberculosis or TB (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body)

Q. Is Solonex DT Tablet chemotherapy/chemotherapy drug?

Solonex DT Tablet is a primary antibiotic used for treatment of tuberculosis. Do not confuse it with chemotherapy or chemo drugs used for the treatment of cancer

Q. Is Solonex DT Tablet bacteriostatic or bactericidal?

Solonex DT Tablet is a bacteriostatic antibiotic. It stops or suppresses growth of tuberculosis causing bacteria by interfering with the formation of protective outer covering (cell wall) which is essential for their growth

Q. Is Solonex DT Tablet safe?

Yes. Solonex DT Tablet is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Q. Is Solonex DT Tablet a MAOI?

Solonex DT Tablet has very weak inhibitory activity on enzymes monoamine oxidases (MAO); however it is not used as a monoamine oxidase inhibitor (MAOI)

Q. Is Solonex DT Tablet a sulfa drug?

No. The chemical structure and mechanism of action of Solonex DT Tablet is different from sulfa drugs

Q. Is Solonex DT Tablet an inducer or inhibitor?

Solonex DT Tablet is an inhibitor (decreases activity) of an important liver enzyme system that is responsible for the final processing and elimination of several drugs from the body

Q. Can I take isoniazid with ibuprofen/Benadryl/Nyquil/Aleve/Mucinex/amoxicillin?

There no known serious drug interactions of isoniazid with ibuprofen, paracetamol (trade name: Tylenol), naproxen (trade name: Aleve), amoxicillin or any active drug present in Nyquil or Mucinex. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects

Q. Does Solonex DT Tablet cause weight loss/weight gain/hair loss/diarrhea/affect menstruation?

Changes in body weight (gain/loss), hair loss, diarrhea or changes in menstruation are not among the known side effects of Solonex DT Tablet. You may experience few of these side effects while on multi drug (including Solonex DT Tablet) treatment for tuberculosis

Q. Does Solonex DT Tablet cause acne/make you tired/cause constipation?

You may experience unusual tiredness, constipation or acne while on treatment with Solonex DT Tablet. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects

Q. Does Solonex DT Tablet affect birth control?

Solonex DT Tablet has no known interaction with commonly used oral contraceptives (birth control pills). However, multidrug treatment for tuberculosis contains active drug rifampin that decreases the effectiveness of oral contraceptives and hampers birth control.

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1555-558.
  2. Chambers HF, Deck DH. Antimycobacterial Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 824-25.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 741-42.
  4. Isoniazid. Nottingham, Nottinghamshire: Boots Contract Manufacturing; 2015. [Accessed 01 Apr. 2019] (online) Available from:External Link
  5. Drugs.com. Isoniazid. [Accessed 01 Apr. 2019] (online) Available from:External Link
  6. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 29 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Macleods Pharmaceuticals Pvt Ltd
Address: Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Country of origin: India

NOT FOR SALE
We do not facilitate sale of this product at present

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.