Soloflox 400mg Tablet

Lomefloxacin (400mg)

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Soloflox 400mg Tablet is an antibiotic, used in the treatment of bacterial infections. It is also used in treating infections of the urinary tract, nose, throat, skin and soft tissues and lungs (pneumonia). It cures the infection by stopping the further growth of the causative microorganisms.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 19 Sep 2025 | 03:31 PM (IST)

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Gurgaon

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General Information

Contains

Lomefloxacin (400mg)

Marketer

Kopran Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Soloflox 400mg Tablet should be used in the dose and duration as advised by your doctor. It may be taken with or without food, preferably at a fixed time. Avoid taking antacids containing aluminum or magnesium within 2 hours before or 2 hours after you take this medicine. Taking antacids, sucralfate, or vitamin or mineral supplements too close to a dose of this medicine, can greatly decrease the effects of the antibiotic. Do not skip any doses and finish the full course of treatment even if you feel better. You should not take a double dose to make up for a missed dose. Simply take the next dose as planned.

You may have a headache, dizziness, nausea, and constipation as side effects of this medicine. These are usually temporary and resolves on its own, but please consult your doctor if it bothers you or persists for a longer duration. Diarrhea may also occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.

You should not take this medicine if you are allergic to any of its ingredients. Special care should be taken in people with kidney problems while taking this medicine.

Uses of Soloflox Tablet

Bacterial infections

Benefits of Soloflox Tablet

Bacterial infections
Soloflox 400mg Tablet is an antibiotic medicine which can be used to treat many different infections caused by bacteria. It stops the growth of the bacteria causing the infection and clears the infection. Take it for as long as prescribed by the doctor and avoid skipping doses. This will make sure that all bacteria are killed and they do not become resistant.

Side effects of Soloflox Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Soloflox

Headache
Dizziness
Nausea
Constipation
Diarrhea

How to use Soloflox Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Soloflox 400mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Soloflox Tablet works

Soloflox 400mg Tablet is an antibiotic medicine to be taken by mouth. It works by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents the bacterial cells from dividing and repairing, thereby killing them.

Quick tips

Your doctor has prescribed Soloflox 400mg Tablet to cure your infection and improve symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better.
Discontinue Soloflox 400mg Tablet and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Your doctor has prescribed Soloflox 400mg Tablet to cure your infection and improve symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better.
Discontinue Soloflox 400mg Tablet and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
Inform your doctor if you are pregnant or planning to conceive or breastfeeding.

Safety advice

Alcohol

SAFE

Consuming alcohol with Soloflox 400mg Tablet does not cause any harmful side effects.

Pregnancy

CONSULT YOUR DOCTOR

Soloflox 400mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Soloflox 400mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

SAFE

Soloflox 400mg Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Soloflox 400mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Soloflox 400mg Tablet may be needed. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Soloflox 400mg Tablet in patients with liver disease. Please consult your doctor.

Interaction with drugs

Taking Soloflox with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not consume Cholera Vaccine (Inactivated) two weeks before and at least 10 days after consuming Lomefloxacin. Please consult your doctor. Lomefloxacin may reduce the efficacy of Cholera Vaccine (Inactivated).

Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Lomefloxacin may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine. Lomefloxacin may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine.

Moderate

Mycophenolate mofetil (Oral Route)

Your doctor may monitor the effects of Mycophenolate mofetil along with your overall treatment and adjust the doses as per the observations. Lomefloxacin may reduce blood levels of Mycophenolate mofetil.

Moderate

Zolmitriptan (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Lomefloxacin may raise blood levels of Zolmitriptan.

Moderate

Acenocoumarol (Oral Route)

Your doctor may frequently monitor your blood clotting time and adjust the dose of Acenocoumarol accordingly.

Frequently asked questions

Can the use of Soloflox 400mg Tablet increase the risk of muscle damage?

Yes, use of Soloflox 400mg Tablet is known to increase the risk of muscle damage, commonly in the ankle (achilies tendon). Muscle damage can happen in people of all ages who take Soloflox 400mg Tablet. Inform your doctor if you feel any kind of muscle pain while using this medicine.

Fact Box

Chemical Class

Fluoroquinolone

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Bacterial DNA Replication Inhibitors- Quinolones/ Fluroquinolones

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 794-95.
PubChem. Lomefloxacin. [Accessed 01 Apr. 2019] (online) Available from:
ScienceDirect. Lomefloxacin. [Accessed 01 Apr. 2019] (online) Available from:
Lomefloxacin. Jan. 2005. [Accessed 01 Apr. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 01 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Kopran Ltd
Address: Parijat House, 1076, Dr. E. Moses Road, Worli, Mumbai - 400 018, Maharashtra (India).

Vendor Details

Country of origin: India

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Why we need a prescription?

Soloflox 400mg Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Soloflox Tablet

Benefits of Soloflox Tablet

Side effects of Soloflox Tablet

How to use Soloflox Tablet

How Soloflox Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Cholera Vaccine (Inactivated) (Oral Route)

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Mycophenolate mofetil (Oral Route)

Zolmitriptan (Oral Route)

Acenocoumarol (Oral Route)

Frequently asked questions

Can the use of Soloflox 400mg Tablet increase the risk of muscle damage?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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