Siroboon 1 Tablet is used for prevention of organ rejection in transplant patients. It regulates the body’s immune response, so the body can accept the new organ.

Siroboon 1 Tablet must be taken in a dose and duration as per the prescription. It can be taken with or without food but make sure to take it at about the same time every day. An overdose of this medicine may have serious side effects on the body.

Common side effects of this medicine include edema, increased blood lipid level, high blood pressure, abdominal pain, diarrhea, headache, fever, urinary tract infection, anemia, nausea, joint pain, and thrombocytopenia. If any of the side effects persist or bother you, consult the doctor immediately. Inform the doctor immediately if you experience any allergic reactions such as rash, shortness of breath, coughing, swelling, etc.

Before taking this medicine, it is important to consult your doctor if you have any ongoing medication for any underlying disease. Pregnant and breastfeeding women must inform the doctor prior to the initiation of this treatment. During the treatment, your doctor may advise you for some laboratory tests to know the effects of the medicine in the body. If you notice signs of infection, any changes in the appearance or size of a mole, unusual growths or lumps, or unusual tiredness or weakness during the treatment, you must consult the doctor immediately.

Uses of Siroboon Tablet

Prevention of kidney transplant rejection

Benefits of Siroboon Tablet

In Prevention of kidney transplant rejection

Siroboon 1 Tablet is used with other medications to prevent kidney transplant rejection. Rejection usually happens due to attack by the immune system of the person receiving the transplanted organ on the transplant itself, in people who are receiving kidney transplants. This medicine reduces the activity of a person's own immune system and prevents any such rejection.

Side effects of Siroboon Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Siroboon

Nausea
Increased blood lipid level
Low blood platelets
Headache
Abdominal pain
Fever
Anemia (low number of red blood cells)
Urinary tract infection
Diarrhea
High blood pressure
Joint pain
Edema (swelling)

How to use Siroboon Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Siroboon 1 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Siroboon Tablet works

Siroboon 1 Tablet is an immunosuppressant. It works by suppressing your body’s immune response following transplant of an organ (eg. liver, kidney, heart). This helps your body to accept the new organ as if it were your own.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Siroboon 1 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Siroboon 1 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Siroboon 1 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

SAFE

Siroboon 1 Tablet does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Siroboon 1 Tablet is safe to use in patients with kidney disease. No dose adjustment of Siroboon 1 Tablet is recommended.

Liver

CAUTION

Siroboon 1 Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Siroboon 1 Tablet may be needed. Please consult your doctor.
Dose adjustment is not recommended in patients with mild to moderate liver disease.

What if you forget to take Siroboon Tablet?

If you miss a dose of Siroboon 1 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Siroboon 1 Tablet

₹140.1/Tablet

Siromus 1mg Tablet

Zydus Cadila

₹169.5/tablet

21% costlier

Rapacan 1mg Tablet

Eris Lifesciences Ltd

₹263.2/tablet

88% costlier

Siropan 1mg Tablet

Panacea Biotec Pharma Ltd

₹230.4/tablet

64% costlier

Sirova 1mg Tablet

Intas Pharmaceuticals Ltd

₹189.1/tablet

35% costlier

Rocas 1mg Tablet

Emcure Pharmaceuticals Ltd

₹124.17/tablet

11% cheaper

View all substitutes

Quick tips

Siroboon 1 Tablet is used to prevent organ rejection following a kidney transplant operation.
Avoid grapefruit juice while you are on treatment with this medicine. This is because a chemical in grapefruit juice increases the amount of Siroboon 1 Tablet in your bloodstream. This makes side-effects more likely.
There is a possibility of a slight increase in the risk of skin cancer with Siroboon 1 Tablet. Do not use sunbeds, and avoid strong sunlight or use a sun cream with a high sun protection factor (SPF of at least 15).
If you have diabetes mellitus, this medicine may affect your blood sugar levels. Monitor your sugar level regularly and report any extreme changes to your doctor.

Fact Box

Chemical Class

Macrolide Lactams

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Immunosuppressant- mTOR inhibitors

Interaction with drugs

Taking Siroboon with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Natalizumab (Oral Route) Life-threatening

Long-term concurrent use may increase the risk of certain brain infections. Do not consume Natalizumab with Sirolimus.

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route) Life-threatening

Concomitant use may cause lethal infections. Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) should not be used while undergoing treatment with Sirolimus or for up to 6... More

Enzalutamide (Oral Route) Severe

Enzalutamide may reduce blood levels of Sirolimus. Do not consume Sirolimus with Enzalutamide. If concurrent use is essential, your doctor may monitor your treatment and adjust th... More

Cholera Vaccine (Inactivated) (Oral Route) Severe

Concomitant use may cause lethal infections. Cholera Vaccine (Inactivated) should not be used while undergoing treatment with Sirolimus or for up to 6 months after stopping Siroli... More

Carbamazepine (Oral Route) Severe

Carbamazepine may reduce blood levels of Sirolimus. Do not consume Sirolimus with Carbamazepine. If concurrent use is essential, your doctor may monitor your treatment and adjust ... More

View all drug interactions

Patient concerns

Heavy Skin Problem With Kidney Transplant Patient

Dr. Souvik Sardar

Dermatology

need a clinical examination of the problem. post clear and focused PICTURES of the problem else visit a dermatologist nearby

Kidney transplant done on 27 the October 2016. Kindly advice about diet after transplant.

Shikha Mishra

Dietetics/Nutrition

Kidney diet should be planned under doctor's guidance so consult where u are going for treatment

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Krensky AM, Bennett WM, Vincenti F. Immunosuppressants, Tolerogens, and Immunostimulants. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1012-13.
Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 972-73.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1267-68.
Sirolimus. Sandwich, Kent: Pfizer Limited; 2001 [revised Oct. 2018]. [Accessed 23 Jan. 2019] (online) Available from:
Sirolimus. Philadelphia, Pennsylvania: Wyeth Pharmaceuticals Inc; 1999. [Accessed 06 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 06 Apr. 2019] (online) Available from:
Sirolimus [Product Description]. Ahmedabad, Gujarat: La Renon Heathcare Pvt. Ltd. [Accessed 06 Apr. 2024] (online) Available from:

Marketer details

Name: Kachhela Medex Pvt Ltd

Address: Shop No. 335, 3rd Floor, Sandesh Dawa Bazar Near Haj House, Ganjipeth, Nagpur 440018

Country of origin: India

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