Sirova 1mg Tablet

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Intas Pharmaceuticals Ltd

Composition for Sirova 1mg Tablet

iconPrescription Required

Primarily used for

Transplant rejection of kidney
1502.51
₹150.25/Tablet
10 tablets in 1 strip
SOLD OUT

Medicine Overview of Sirova Tablet

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Uses of Sirova Tablet

Sirova 1mg Tablet is used in transplant rejection of kidney.
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Side effects of Sirova Tablet

Common

Nausea, Headache, Abdominal pain, Viral infection, Pneumonia, Reduced blood platelets, Increased heart rate, Decreased white blood cell count, Anemia, Urinary tract infection, Diarrhoea, Increased blood pressure, Bacterial infection, Fungal infection, Constipation, Herpes virus infection.

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How to use Sirova Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It can be taken with or without food, but it is better to take Sirova 1mg Tablet at a fixed time.

How Sirova Tablet works

Sirova 1mg tablet suppresses the activity of body's immune system and prevents rejection of the transplanted organ.

In Depth Information on Sirova Tablet

Expert advice for Sirova Tablet

  • You may be frequently monitored for renal function during concomitant administration of sirolimus and ciclosporin.
  • Sirolimus increase risk of infection and the risk of developing certain types of cancer (e.g., lymphoma, skin cancer). Seek immediate medical attention if you notice signs of infection (e.g., persistent sore throat, chills, and fever), any changes in the appearance or size of a mole, night sweats, unusual growths or lumps, or unusual tiredness or weakness.
  • Avoid use of live vaccines during treatment as the vaccination may be less effective when taking sirolimus.
  • Use effective methods of contraception during sirolimus therapy and for 12 weeks after sirolimus has been stopped.
  • Consult your doctor if you develop any liver problems, kidney problems, high cholesterol or triglycerides, low blood platelet levels, diabetes or high blood sugar, or lung or breathing problems or if you are considered to be at high risk for rejection, such as if you had a previous transplant that was lost to rejection.
  • Limit the exposure to sunlight and UV light by covering your skin with clothing and using a sunscreen with a high protection factor because of the increased risk for skin cancer, when receiving sirolimus.
  • Take sirolimus at the same time in relation to ciclosporin, and consistently with or without food, as its blood levels will be monitored.
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Warnings
Special precautions for Sirova 1mg Tablet
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Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
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Pregnancy
WEIGH RISKS VS BENEFITS
Sirova 1mg Tablet may be unsafe to use during pregnancy.

Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
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Lactation
CAUTION
Sirova 1mg Tablet is probably usafe to use during lactation.
Limited human data suggests that the drug could represent a significant risk to the baby.
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Driving
SAFE
Sirova 1mg Tablet does not usually affect your ability to drive.
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Kidney
SAFE
Sirova 1mg Tablet is safe to use in patients with kidney dis
ease. No dose adjustment of Sirova 1mg Tablet is recommended.
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Liver
There is no data available. Please consult doctor before consuming the drug.
Severely interacts with other drugs like
Zathrin Redimix Suspension, Pratham 200mg Suspension, Azifine 200mg Suspension, Azibig - 100 Suspension

Patient Concerns

Frequently asked questions for Sirova 1mg Tablet

Frequently asked questions for Sirolimus

Sirova is not dialyzable to significant extent. i.e. it will not be eliminated after dialysis.
Sirova is not a calcineurin inhibitor, but it has a similar suppressive effect on the immune system
Sirova is a cytotoxic agent
The Sirova-eluting stent is a metal stent coated with 140 µg/cm2 of Sirova blended with synthetic polymers. After stent implantation, Sirova is slowly released causing localized inhibition of growth of smooth muscle cells in the wall of the blood vessel in which it is implanted over a period of about 1 month
Sirova causes hair loss
Sirova alters certain body pathways to increase lipid/fat synthesis by the liver, thereby causing hyperlipidemia.
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