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Sinopil 2mg Tablet

Lacidipine (2mg)
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Sinopil 2mg Tablet is a medicine used to treat high blood pressure (hypertension). It belongs to a class of medicines known as calcium channel blocker which helps to lower blood pressure and reduce the workload of the heart. This helps prevent heart attacks and strokes.

Written By Dr. Mayank, Pharm.D,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 19 Sep 2025 | 03:30 PM (IST)
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Sinopil 2mg Tablet image
Sinopil 2mg Tablet image

Product introduction

Sinopil 2mg Tablet also helps to prevent the buildup of plaque (cholesterol deposit) in your arteries wall. It may be prescribed alone or along with other medicines. The dose depends on your blood pressure levels and the severity of your condition. You can take it at any time of the day, with or without food, but it is best to take it at the same time each day. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight, and eating a healthy diet will also help control your blood pressure. Follow your doctor’s advice while taking this medicine.

The most common side effects include nausea, fatigue, abdominal pain, edema, dizziness, flushing, headache, itching, rash, erythema, and palpitations. Consult your doctor if any of these bother you, or do not go away.

Before taking it, let your doctor know if you have any liver, kidney, or heart problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking, especially those used to treat high blood pressure or heart conditions. You should have your blood pressure checked regularly to make sure that this medicine is working properly.

Benefits of Sinopil Tablet

Hypertension (high blood pressure)
Sinopil 2mg Tablet is a calcium channel blocker. It works by relaxing the blood vessels so that blood can flow more easily around your body. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. Take regularly, as prescribed for this medicine to be most effective, even if you feel better.

Side effects of Sinopil Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sinopil
  • Edema (swelling)
  • Dizziness
  • Palpitations
  • Abdominal pain
  • Headache
  • Nausea
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Rash
  • Itching
  • Frequent urge to urinate
  • Erythema (skin redness)

How to use Sinopil Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sinopil 2mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Sinopil Tablet works

Sinopil 2mg Tablet is a calcium channel blocker. It regulates the blood pressure by relaxing the blood vessels and reducing the pressure on them, thereby making it easier for the heart to pump more blood throughout the body. In this way, it normalizes the blood pressure in patients with high blood pressure.

Quick tips

  • A sudden drop in your blood pressure may occur, especially when you first start taking Sinopil 2mg Tablet. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • It can cause ankle or foot swelling. To reduce the swelling, raise your legs while you are sitting down. Talk to your doctor if it does not go away.
  • It may cause dizziness. Do not drive or perform any activity that requires mental focus until you know how Sinopil 2mg Tablet affects you. 
  • Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding. 
  • You have been prescribed Sinopil 2mg Tablet to improve your blood pressure and/or to reduce the number and severity of angina attacks.
  • Lowering blood pressure reduces the chance of future heart attack and stroke.
  • Take it at the same time every day to help you remember to take it.
  • A sudden drop in your blood pressure may occur, especially when you first start taking Sinopil 2mg Tablet. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • It can cause ankle or foot swelling. To reduce the swelling, raise your legs while you are sitting down. Talk to your doctor if it does not go away.
  • It may cause dizziness. Do not drive or perform any activity that requires mental focus until you know how Sinopil 2mg Tablet affects you. 
  • Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding. 

Safety advice

Alcohol

Alcohol

CAUTION
Caution is advised when consuming alcohol with Sinopil 2mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Sinopil 2mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Sinopil 2mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving

Driving

UNSAFE
Sinopil 2mg Tablet may cause side effects which could affect your ability to drive.
Kidney

Kidney

SAFE IF PRESCRIBED
Sinopil 2mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Sinopil 2mg Tablet may not be needed in these patients. Please consult your doctor.
Liver

Liver

CAUTION
Sinopil 2mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Sinopil 2mg Tablet may be needed. Please consult your doctor.

Interaction with drugs

Taking Sinopil with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Estradiol (Oral Route)

Do not use Estradiol with Lacidipine, especially if you have heart disease. If concurrent use is essential, talk to your doctor and monitor your blood pressure regularly.
Moderate

Progesterone (Oral Route)

Do not use Progesterone with Lacidipine, especially if you have heart disease. If concurrent use is essential, talk to your doctor and monitor your blood pressure regularly.
Moderate

Progesterone (Natural Micronized) (Oral Route)

Do not use Progesterone (Natural Micronized) with Lacidipine, especially if you have heart disease. If concurrent use is essential, talk to your doctor and monitor your blood pressure regularly.
Moderate

Carbamazepine (Oral Route)

Your doctor may monitor your treatment and adjust the doses as per the observations. Carbamazepine may reduce blood levels of Lacidipine.
Moderate

Cilostazol (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Frequently asked questions

Sinopil 2mg Tablet is a medicine used to treat high blood pressure. It belongs to a group of medicines which block the calcium channels in the blood vessel. It works by relaxing the blood vessels in patients with high blood pressure. This widens the diameter of the blood vessels which helps the blood to pass through them more easily.
No, do not stop taking Sinopil 2mg Tablet on your own, as it may worsen your condition. You should take the medicine in the dose and duration advised by your doctor.
Avoid eating grapefruit (chakotra) or drinking grapefruit juice while taking Sinopil 2mg Tablet. Take a low sodium and low fat diet, and adhere to the lifestyle changes as advised by your doctor.
Sinopil 2mg Tablet may be taken with or without food, but it is better to take it at a fixed time everyday. This reduces the chances of missing doses and also helps to maintain a consistent level of medicine in your body.
Sinopil 2mg Tablet can cause ankle or foot swelling. Raise your legs while you are sitting down. Talk to your doctor if it does not go away.
Yes. Sinopil 2mg Tablet can cause dizziness as a side effect. If you experience dizziness sit or lie down until the symptoms pass. However, this is temporary and usually goes away as the treatment continues. Also, avoid alcohol intake during the course of treatment as it may worsen the dizziness.

Fact Box

Chemical Class

Dihydropyridines derivatives

Habit Forming

No

Therapeutic Class

CARDIAC

Action Class

Calcium Channel Blockers- Dihydropyridines (DHP)

Related lab tests

References

  1. Opie LH, Krum H, Victor RG, et al. Antihypertensive Therapies. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 244.
  2. Lacidipine. Beverley, Hull: Dr. Reddy's Laboratories (UK) Ltd.; 2014 [revised 04 Mar. 2019]. [Accessed 19 Mar. 2019] (online) Available from:
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Glaxo SmithKline Pharmaceuticals Ltd
Address: Dr. Annie Besant Road, Mumbai - 400 030

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Sinopil 2mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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