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Simvas 5mg Tablet

Written By Dr. Syeda Aafia, MBA, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 01 Jan 2026 | 09:03 PM (IST)
Simvas 5mg Tablet belongs to a group of medicines called statins. It is used to lower cholesterol and triglycerides and reduce the risk of heart disease. Cholesterol is a fatty substance that builds up in your blood vessels and causes narrowing, which may lead to a heart attack or stroke.
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General Information

The content is shown in English
Simvas 5mg Tablet image
Simvas 5mg Tablet image

Product introduction

Simvas 5mg Tablet is usually taken in the evening, with or without food. However, taking it with food may reduce the chances of nausea. Take it regularly for maximum benefit. Most people with high cholesterol and triglycerides do not feel ill, but stopping the medicine may increase cholesterol and triglyceride levels, making the condition worse and increasing the risk of heart disease and stroke.


It is important to have your cholesterol levels checked regularly. This medicine is only one part of the treatment program, which should also include a healthy diet, regular exercise, smoking cessation, moderation of alcohol intake, and weight reduction. You can eat normally while taking this medicine, but try to avoid foods that are high in fat.


Common side effects of Simvas 5mg Tablet include upper respiratory infections, headache, abdominal pain, constipation, and nausea. These are usually mild and temporary. Consult your doctor if they persist. Inform your doctor if you notice any yellowing of your eyes or get repeated or unexplained muscle pains.


Simvas 5mg Tablet should not be used in individuals with severe liver disease. Also, pregnant and breastfeeding women should not take this medicine as it may harm the baby. Diabetic patients should monitor their blood sugar levels while taking this medicine, as it may lead to an increase in blood sugar levels.

Uses of Simvas Tablet

Benefits of Simvas Tablet

Prevention of heart attack and stroke
High levels of cholesterol can cause your blood vessels to narrow (atherosclerosis) and put you at risk of having a stroke or heart disease. Lowering the amount of this fat reduces the chances of this happening and helps you remain healthier for longer. Keep taking this medicine even if you feel well.

Side effects of Simvas Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Simvas
  • Constipation
  • Headache
  • Upper respiratory tract infection
  • Abdominal pain
  • Nausea

How to use Simvas Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Simvas 5mg Tablet may be taken with or without food.

How Simvas Tablet works

Simvas 5mg Tablet is a lipid-lowering medication (statin). It works by blocking an enzyme (HMG-CoA-reductase) that is required in the body to make cholesterol. It thus lowers "bad" cholesterol (LDL) and triglycerides, raising the level of "good" cholesterol (HDL).

All substitutes for Simvas 5mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Simvas 5mg Tablet should be taken in the evening after dinner and before sleeping.
  • Take this medicine along with regular exercise and a low-fat diet to lower levels of fat in the blood.
  • Inform your doctor if you experience fatigue, muscle weakness, or muscle pain.
  • Your doctor may check your liver function before starting the treatment and regularly thereafter. Inform your doctor if you notice signs of liver problems, such as stomach pains, unusually dark urine, or yellowing of skin or eyes.
  • Inform your doctor if you have kidney disease, liver disease, or diabetes before starting treatment with this medicine. If you are diabetic, monitor your blood sugar level regularly as Simvas 5mg Tablet may cause an increase in your blood sugar level.
  • Do not take Simvas 5mg Tablet if you are pregnant, planning a pregnancy, or breastfeeding.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Simvas 5mg Tablet
Pregnancy

Pregnancy

UNSAFE
Simvas 5mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

UNSAFE
Simvas 5mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Simvas 5mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Simvas 5mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Simvas 5mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Simvas 5mg Tablet is not recommended in patients with severe liver disease and active liver disease.

Interaction with drugs

Taking Simvas with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Atazanavir (Oral Route)

Do not consume Simvastatin with Atazanavir. Atazanavir may raise blood levels of Simvastatin.
Life-threatening

Ciclosporin (Oral Route)

Do not consume Simvastatin with Ciclosporin. If concurrent use is essential, watch out for symptoms such as decreased blood pressure, headache or swelling. Please consult your doctor. Ciclosporin may raise blood levels of Simvastatin.
Life-threatening

Ciclosporin (Injection Route)

Do not consume Simvastatin with Ciclosporin. If concurrent use is essential, watch out for symptoms such as decreased blood pressure, headache or swelling. Please consult your doctor. Ciclosporin may raise blood levels of Simvastatin.
Life-threatening

Clarithromycin (Oral Route)

Do not consume Simvastatin with Clarithromycin. If Clarithromycin is essential, your doctor may temporarily stop Simvastatin. Clarithromycin may raise blood levels of Simvastatin.
Life-threatening

Clarithromycin (Injection Route)

Do not consume Simvastatin with Clarithromycin. If Clarithromycin is essential, your doctor may temporarily stop Simvastatin. Clarithromycin may raise blood levels of Simvastatin.

Frequently asked questions

Cholesterol is a type of fat present in your blood. Total cholesterol is determined by the total amount of LDL and HDL cholesterol in the body. LDL cholesterol is called “bad” cholesterol. Bad cholesterol can build up in the walls of your blood vessels and slow or obstruct blood flow to your heart, brain, and other organs. This can cause heart disease and stroke. HDL cholesterol is called “good” cholesterol as it prevents the bad cholesterol from building up in the blood vessels. High levels of triglycerides are also harmful to you.
Yes, Simvas 5mg Tablet is safe to use if used as prescribed by the doctor and if the doctor's instructions are followed. The side effects of this medicine are few and do not occur in everyone.
Simvas 5mg Tablet is a medicine that helps lower bad cholesterol and fats like triglycerides in your blood. It also helps raise good cholesterol. It is usually taken along with a healthy diet and regular exercise. It works by slowing down the amount of cholesterol made by your liver. This helps prevent cholesterol from building up in your blood vessels, which can lower your risk of heart problems like heart attacks and strokes.
Simvas 5mg Tablet is generally taken once a day, preferably in the evening after dinner. Try taking this medicine at the same time every day to help remember when to take it.
You may need to take Simvas 5mg Tablet for life or for as long as directed by your doctor. The cholesterol levels will be maintained only till you are taking Simvas 5mg Tablet. Stopping Simvas 5mg Tablet without starting a different treatment may increase your cholesterol levels again. This medicine has only a few side effects and is usually considered safe if taken as directed by the doctor.
Simvas 5mg Tablet is used to decrease your blood cholesterol levels. Therefore, to seek the best results of this medicine, you should avoid foods which are high in calories like fried food and junk food. It is recommended to eat a low-fat and low-cholesterol diet. Be sure to follow all the exercise and dietary recommendations made by your doctor or dietician.
No, it is not advised to take alcohol with Simvas 5mg Tablet. This is because the risk of developing liver problems increases if you drink alcohol while taking this medicine. Moreover, there is a significant increase in the triglyceride levels if Simvas 5mg Tablet is taken along with alcohol. This can further lead to liver damage and also worsen some of the side effects such as muscle pain, muscle weakness and tenderness. People with liver problems are therefore advised not to take Simvas 5mg Tablet without consulting their doctor. They must also refrain from consuming alcohol while taking this medicine to get maximum benefit.

Fact Box

Chemical Class

Delta valerolactones

Habit Forming

No

Therapeutic Class

CARDIAC

Action Class

HMG-CoA Reductase Inhibitors (Statins)

References

  1. Bersot TP. Drug Therapy for Hypercholesterolemia and Dyslipidemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 893-902.
  2. Gotto AM Jr, Opie LH. Lipid-Modifying Antiatherosclerotic Drugs. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 418-19.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1266-67.
  4. Simvastatin [FDA Label]. Cramlington, Northumberland, UK: Merck Sharp & Dohme Ltd.; 2012. [Accessed 20 Apr. 2020]. (online) Available from:
  5. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Simvastatin. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
  7. Simvastatin [Drug Label]. Whitehouse Station, NJ: Merck & Co. Inc.; 2012. [Accessed 25 Jul. 2024] (online) Available from:
  8. Simvastatin [FDA Label]. Goa, India: Micro labs Ltd.; 2023. [Accessed 22 Feb. 2025]. (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Micro Labs Ltd
Address: Mamring Namthang Road, Namchi-737132, Sikkim || 27, RACE COURSE ROAD, BANGALORE-560 001, INDIA || Plot no 37 (CA) 147-151 , 279-281 ,Ground Mezzanine , 1st & 2nd Floor K.I.A.D.B JIgani Bomasandra , Link Road, Bangalore - 562106, India

Vendor Details

Country of origin: India
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