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Seroflo 250 Multihaler

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 13 Apr 2026 | 10:23 AM (IST)
Seroflo 250 Multihaler is a combination of two medicines that opens the airways and makes it easier to breathe. It is used in the treatment of asthma (wheezing and shortness of breath) and chronic obstructive pulmonary disorder (a lung disorder in which the flow of air to the lungs is blocked).
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The content is shown in English
Seroflo 250 Multihaler image
Seroflo 250 Multihaler image

Product introduction

Your doctor will tell you how often you need to use your inhaler. The effect of this medicine may be noticeable after a few days but will only reach its maximum after a few weeks. This medicine must be used regularly to be effective, so go on taking it even if you don't have any symptoms. That means it’s doing its job. If you stop taking it your asthma and chronic obstructive pulmonary disorder (COPD) may get worse. It should not be used to relieve sudden asthma attacks. If an asthma attack occurs, use your quick-relief inhaler (reliever). To get the benefit from this medicine you need to make sure you get your inhaler technique right, otherwise, it does not work as well.

The most common side effects are nausea, vomiting, respiratory tract infection, fungal infections in the mouth, headache, hoarseness of voice, sore throat, cough, musculoskeletal (bone, muscle, or joint) pain, and increased heart rate. If you get there, do not stop taking it but do talk to your doctor. You can help prevent some of these symptoms by rinsing your mouth and throat with water or brushing your teeth after using your inhaler. There are other, rarer side effects that can be serious. Talk to your doctor if you're worried about them. In general, you should be trying to avoid situations that make your asthma worse (your triggers) and try not to smoke.

Ask your doctor whether it’s safe to take this medicine if you're pregnant or breastfeeding. Before taking it, you should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.

Benefits of Seroflo Multihaler

Treatment of Asthma
Seroflo 250 Multihaler can help prevent the onset of an asthma attack if it is taken before exercise or exposure to some “triggers”. These may include house dust, pollen, pets and cigarette smoke. This medicine will allow you to exercise more freely without worrying about getting symptoms such as wheezing, coughing and shortness of breath. It allows you to live your life more freely without worrying so much about things that set off your symptoms.
Treatment of Chronic obstructive pulmonary disease (COPD)
Seroflo 250 Multihaler helps the airways in your lungs stay open. It relaxes the muscles of these airways. This makes it easier for air to get in and out. It will relieve symptoms such as tightness in your chest, shortness of breath, wheezing and coughing and help you carry out your daily activities more easily. This medicine is safe and effective. It usually starts to work within a few minutes and the effects can last up to several hours. Do not stop using it unless you are advised to by your doctor.

Side effects of Seroflo Multihaler

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Seroflo
  • Cough
  • Upper respiratory tract infection
  • Nasopharyngitis (inflammation of the throat and nasal passages)
  • Sinus inflammation
  • Stomach discomfort
  • Fungal infection of oropharynx
  • Voice change
  • Headache
  • Aggressive behavior
  • Dryness in mouth

How to use Seroflo Multihaler

Check the label for directions before use. Hold the multihaler by the base and open the mouth piece cover. Slide the knob until you a hear a click. Place the mouthpiece between your lips and breath in deeply. Remove the multihaler and hold your breath for 10 seconds. Afterwards, rinse your mouth thoroughly with water and spit it out.

How Seroflo Multihaler works

Seroflo 250 Multihaler is a combination of two medicines: Salmeterol and Fluticasone Propionate. Salmeterol is a long-acting bronchodilator which works by relaxing the muscles in the airways and widens the airways. Fluticasone Propionate is a steroid. It works by stopping the release of certain chemical messengers that cause inflammation (swelling) of the airways. Together, they make breathing easier.

Quick tips

  • This medicine is for inhalation only. The tablet should not be swallowed.
  • It should be taken at the same time each day.
  • It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing. 
  • Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
  • Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat.
  • Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using.
  • Your doctor may regularly monitor your  blood potassium level as low oxygen level in the blood (hypoxia) and medicines such as Seroflo 250 Multihaler can lower blood potassium level.
  • Only miniscule amounts of Seroflo 250 Multihaler may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Seroflo 250 Multihaler. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Seroflo 250 Multihaler during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Seroflo 250 Multihaler should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

UNSAFE
Seroflo 250 Multihaler may cause side effects that could affect your ability to drive.
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

Seroflo 250 Multihaler is an inhalation medication that helps in reducing symptoms associated with obstructive airway diseases like asthma and chronic obstructive pulmonary disease (COPD).
Seroflo 250 Multihaler contains salmeterol, a long-acting beta-2-adrenergic agonist and fluticasone, a corticosteroid. Salmeterol relaxes bronchial smooth muscles causing bronchodilation and fluticasone reduces inflammation.
Seroflo 250 Multihaler is a controller medication to be used on a regular basis as prescribed by the doctor. It does not help to relive the sudden worsening of respiratory symptoms.
Yes, it contains steroids that are effective in improving breathing difficulty due to COPD and asthma. Inhaled corticosteroids have a lower side effect profile as compared to steroid injections and tablets.
Some individuals taking Seroflo 250 Multihaler may experience an increase in heart rate. If this occurs, one should contact his/her doctor immediately.
The most common side effects of Seroflo 250 Multihaler are upper respiratory infection, headache, throat irritation, hoarseness and voice changes, dizziness, nausea, and vomiting.
Seroflo 250 Multihaler is not at all addictive. It is a very effective and useful medicine for people suffering from breathing difficulties due to asthma and COPD.
No, you should not take Seroflo 250 Multihaler more frequently than recommended by your doctor. It will increase the risk of side effects rather than providing additional therapeutic benefits. However, if you feel the symptoms are not relieved by the given doses, consult the doctor for reevaluation.
The missed dose can be taken as soon as possible. If it is time for the next dose, take the scheduled dosing and skip the missed dose.
Seroflo 250 Multihaler is a breath actuated inhaler (BAI), hence it is very easy to use. It overcomes the issue of patient coordination of actuation with inhalation. Refer to its leaflet or speak to your doctor to understand how to use the inhaler.
Seroflo 250 Multihaler may cause an increase in blood sugar levels, hence the blood sugar levels should be cautiously monitored. Consult your doctor for further information.
Always use the Seroflo 250 Multihaler in the right way. If any worsening of symptoms or side effects occurs, inform your doctor about it. Rinse your mouth with water after using the inhaler every time. Maintain good oral hygiene.
Seroflo 250 Multihaler should be stored at room temperature, away from heat and direct light. It should be kept away from the reach of children and pets.

Fact Box

Habit Forming

No

Therapeutic Class

RESPIRATORY
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User feedback

Twice A Day
47%
Once A Day
47%
Thrice A Day
7%
Asthma
67%
Chronic obstructive pulmonary disease (COPD)
22%
Others
11%
Excellent
83%
Average
17%
No Side Effect
100%
With food
50%
With or without food
50%
Expensive
100%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India
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