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Semigaba 50mg Tablet

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 18 Feb 2026 | 05:12 PM (IST)
Semigaba 50mg Tablet is a medicine used to relieve pain caused by nerve damage (neuropathic pain) due to diabetes, shingles (herpes zoster infection), spinal cord injury, or other conditions. It is also used to treat widespread muscle pain and stiffness in people with fibromyalgia.
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General Information

Contains

Pregabalin (50mg)

Marketer

Auxesia Life Sciences Private Limited

Storage

Store below 30°C
The content is shown in English
Semigaba 50mg Tablet image
Semigaba 50mg Tablet image

Product introduction

You can take Semigaba 50mg Tablet with or without food, but it is important to take this medicine at the same time each day to get the most benefit. The exact dose and duration of treatment will depend on your condition and how you respond to it. Your doctor will probably start this medicine at a low dose and increase it gradually. It may take a few weeks for the medicine to work properly. Follow your doctor’s instructions and continue taking it regularly until your doctor advises you to stop. Do not miss any dose, otherwise, your condition may worsen.

The side effects of this medicine are usually mild and go away by themselves. The most common ones are feeling sleepy or dizzy, dryness in the mouth, blurred vision, weight gain, edema (swelling over the whole body), and difficulty in concentrating. Most side effects are not serious and do not need medical attention. Talk to your doctor about potential side effects and ways in which you might prevent or cope with them.

Before taking the medicine you should tell your doctor if you are pregnant, breastfeeding, or planning to become pregnant. Be careful while driving as sleepiness, dizziness, and blurring of vision may be seen as side effects. You should avoid drinking alcohol along with this medicine as it may lead to excessive sleepiness and dizziness.

Uses of Semigaba Tablet

Benefits of Semigaba Tablet

Treatment of Neuropathic pain
Neuropathic pain occurs due to nerve damage and is often felt as burning, tingling, or shooting pain. Semigaba 50mg Tablet reduces this nerve-related pain, leading to better comfort, improved sleep, and enhanced quality of life.
Treatment of Fibromyalgia
Fibromyalgia is a long-term condition that causes widespread muscle pain, tiredness, and sleep problems. Semigaba 50mg Tablet helps relieve the persistent pain and discomfort linked to this condition, improving sleep and making daily activities easier.

Side effects of Semigaba Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Semigaba
  • Weight gain
  • Dryness in mouth
  • Peripheral edema
  • Sleepiness
  • Blurred vision
  • Dizziness

How to use Semigaba Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Semigaba 50mg Tablet may be taken with or without food.

How Semigaba Tablet works

Semigaba 50mg Tablet is an antiepileptic medication. When given for epilepsy, it is believed to work by reducing the abnormal electrical activity in the brain, thus preventing seizures. It is also used to treat nerve and muscle pain where it blocks pain by interfering with pain signals traveling through the damaged nerves and the brain.

All substitutes for Semigaba 50mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Gabawin 50 Tablet

by Icon Life Sciences
₹11.5/tablet
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<h3 class=bodySemiBold>Gabawin 50 Tablet</h3>

Pregaque 50mg Tablet

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₹11.8/tablet
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<h3 class=bodySemiBold>Pregaque 50mg Tablet</h3>

Quick tips

  • Semigaba 50mg Tablet should be taken as per the dose and duration prescribed by your doctor.
  • It may cause sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • It may cause blurring or loss of vision. Inform your doctor immediately if you notice any vision changes.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
  • Do not stop taking the medication suddenly without talking to your doctor as it may worsen your underlying condition.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Semigaba 50mg Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Semigaba 50mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Semigaba 50mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Semigaba 50mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Semigaba 50mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

SAFE IF PRESCRIBED
Semigaba 50mg Tablet is safe to use in patients with liver disease. No dose adjustment is recommended.

Interaction with drugs

Taking Semigaba with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Orlistat (Oral Route)

Watch out for symptoms such as tremors. seizures or impaired coordination and consult your doctor if you experience them. Your doctor may consider separating the administration of Orlistat and Pregabalin. Orlistat may reduce efficacy of Pregabalin.
Moderate

Clozapine (Oral Route)

If concurrent use is essential, watch out for symptoms of Clozapine side effects such as blurred vision, sleepiness, headache, constipation, nausea, dizziness, faintness or fatigue and consult your doctor if you experience them. They may adjust the dose of Clozapine accordingly. Clozapine may raise blood levels of the active form of Pregabalin.
Moderate

Buprenorphine (Injection Route)

If concurrent use is essential, watch out for symptoms of Buprenorphine side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Buprenorphine as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Moderate

Buprenorphine (Oral Route)

If concurrent use is essential, watch out for symptoms of Buprenorphine side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Buprenorphine as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Moderate

Buprenorphine (Transdermal Route)

If concurrent use is essential, watch out for symptoms of Buprenorphine side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Buprenorphine as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.

Frequently asked questions

Semigaba 50mg Tablet belongs to the anticonvulsants class of medicines. It is used to treat seizures. It is also helpful in treating nerve pain (neuropathic pain) which could be due to diabetes, shingles, or injury. It is also used in fibromyalgia (a long-lasting condition that may cause pain, tiredness, muscle stiffness and tenderness as well as difficulty falling or staying asleep. In some cases, your doctor may prescribe this medicine for the treatment of anxiety.
No, Semigaba 50mg Tablet works in different ways for different diseases. In epilepsy, it stops seizures by reducing the abnormal electrical activity in the brain. In chronic pain, it blocks pain messages travelling from brain to spine.
It may take a few weeks to see full benefits while taking Semigaba 50mg Tablet. However, people have experienced relief from pain after a week of starting Semigaba 50mg Tablet.
Duration for the use of Semigaba 50mg Tablet depends on the condition for which you are taking this medicine. If you are taking it for epilepsy, and it is effectively helping you then, you may have to continue it for years. If you are taking it for neuropathic or fibromyalgia pain, it is likely that once your symptoms improve you will have to continue taking it for several months. This will ensure that the problem does not come back. It is advised not to stop taking this medicine without consulting your doctor.
Yes, you should not stop taking Semigaba 50mg Tablet even if you feel fine. If you are taking it for epilepsy and stop its consumption suddenly, you may have seizures that will not stop. Stopping it suddenly may result in withdrawal symptoms and you may experience anxiety, difficulty in sleeping, feeling sick, pain and sweating. These can be prevented if the dose of Semigaba 50mg Tablet is reduced gradually.
Addiction to Semigaba 50mg Tablet is more common in people who take it for unauthorized reasons. Taking Semigaba 50mg Tablet more than the recommended doses or taking it for long periods of time may also cause addiction. In addition to that, any person who has a history of drug abuse should never use Semigaba 50mg Tablet. In case you feel you are becoming physically dependent on Semigaba 50mg Tablet, inform your doctor immediately.
Yes, Semigaba 50mg Tablet and Diazepam can be used together. But, there might be a chance of increased side effects since both these medicines act on the brain to depress excessive activity.
Semigaba 50mg Tablet belongs to the anticonvulsants class of medicines. It is used to treat seizures. It is also helpful in treating nerve pain (neuropathic pain) which could be due to diabetes, shingles, or injury. It is also used in fibromyalgia (a long-lasting condition that may cause pain, tiredness, muscle stiffness and tenderness as well as difficulty falling or staying asleep. In some cases, your doctor may prescribe this medicine for the treatment of anxiety.
No, Semigaba 50mg Tablet works in different ways for different diseases. In epilepsy, it stops seizures by reducing the abnormal electrical activity in the brain. In chronic pain, it blocks pain messages travelling from brain to spine.
It may take a few weeks to see full benefits while taking Semigaba 50mg Tablet. However, people have experienced relief from pain after a week of starting Semigaba 50mg Tablet.
Duration for the use of Semigaba 50mg Tablet depends on the condition for which you are taking this medicine. If you are taking it for epilepsy, and it is effectively helping you then, you may have to continue it for years. If you are taking it for neuropathic or fibromyalgia pain, it is likely that once your symptoms improve you will have to continue taking it for several months. This will ensure that the problem does not come back. It is advised not to stop taking this medicine without consulting your doctor.
Yes, you should not stop taking Semigaba 50mg Tablet even if you feel fine. If you are taking it for epilepsy and stop its consumption suddenly, you may have seizures that will not stop. Stopping it suddenly may result in withdrawal symptoms and you may experience anxiety, difficulty in sleeping, feeling sick, pain and sweating. These can be prevented if the dose of Semigaba 50mg Tablet is reduced gradually.
Addiction to Semigaba 50mg Tablet is more common in people who take it for unauthorized reasons. Taking Semigaba 50mg Tablet more than the recommended doses or taking it for long periods of time may also cause addiction. In addition to that, any person who has a history of drug abuse should never use Semigaba 50mg Tablet. In case you feel you are becoming physically dependent on Semigaba 50mg Tablet, inform your doctor immediately.
Yes, Semigaba 50mg Tablet and Diazepam can be used together. But, there might be a chance of increased side effects since both these medicines act on the brain to depress excessive activity.
Yes, Semigaba 50mg Tablet may cause weight gain because it increases your hunger. Regular physical exercise and a balanced diet with low-calorie food may help you keep your weight stable. Consult a dietician if you have any further concerns to keep your weight stable.

Fact Box

Chemical Class

Gamma amino acid derivative

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Alpha-2 Delta Ligands- Antiepileptic Drugs (AEDs)

References

  1. Stahl SM, editor. Pregabalin. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 557-60.
  2. McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 599.
  3. Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 410.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1149.
  5. Pregabalin. Vega Baja, Puerto Rico: Pfizer Pharmaceuticals LLC; 2009. [Accessed 23 Jan. 2019] (online) Available from:
  6. Pregablin. New York, New York: Pfizer; 2004 [revised Jun. 2011]. [Accessed 22 Mar. 2019] (online) Available from:
  7. Pregabalin. Sandwich, Kent: Pfizer Limited; 2009 [revised July 2018]. [Accessed 22 Mar. 2019] (online) Available from:
  8. Pregabalin. Beverley, Hull: Dr. Reddy's Laboratories (UK) Ltd.; 2015 [revised 01 May 2018]. [Accessed 17 Jun. 2019]. (online) Available from:
  9. National Health Service. Pregabalin; 2018. [Accessed 17 Jun. 2019] (online) Available from:
  10. Lyrica (pregabalin): Frequently asked questions. [Accessed 17 Jun. 2019]. (online) Available from:
  11. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Pregabalin. [Updated 2019 Oct 23]. [Accessed 20 Feb. 2020] (online) Available from:
  12. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
  13. Pregabalin [Package Insert]. Solan, Himachal Pradesh: Torrent Pharmaceuticals Ltd. [Accessed 05 Aug. 2023] (online) Available from:
  14. Pregabalin [Prescribing Information]. India: Alembic Pharmaceuticals Limited; 2023. [Accessed 05 Aug. 2023] (online) Available from:
  15. Pregabalin. Prescribing Information. Viatris Specialty LLC. 2025. [Accessed 10 Sep. 2025] (online) Available from:
  16. Pregabalin [Prescribing Information]. Morgantown, WV: Viatris Specialty LLC; 2025. [Accessed 06 Nov. 2025] (online). Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Auxesia Life Sciences Private Limited
Address: 26/494b, Darshanam Towers. Friends Nagar, Cochin- 682013,Kerala

Vendor Details

Country of origin: India

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