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MRP: Rs. 46.50 for 1 strip(s) (10 tablets each)
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Composition for SELGIN

Selegiline(10 mg)

food interaction for SELGIN

alcohol interaction for SELGIN

pregnancy interaction for SELGIN

lactation interaction for SELGIN

It is better to take Selgin 10 mg tablet with food.
Interaction with alcohol is unknown. Please consult your doctor.
Selgin 10 mg tablet may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Selegiline(10 mg)


Selgin 10 mg tablet is used alone or in combination with levodopa and carbidopa to control the symptoms of Parkinson’s disease (a disorder of the nervous system that causes difficulties with movement, muscle control, and balance).

How it works

Selgin 10 mg tablet belongs to the class of medication called monoamine oxidase-B inhibitor. It prevents the breakdown of a chemical called dopamine (a natural substance that is needed to control movement; also obtained after chemical conversion of levodopa) in the brain. It prolongs the action of levodopa, decreases the dose of levodopa/carbidopa needed to control symptoms, stops the effects of levodopa/carbidopa from wearing off between doses.

Common side effects

Vomiting, Nausea, Nightmare, Constipation, Depression, Diarrhoea, Abdominal pain, Dizziness, Dry mouth, Difficulty in swallowing, Fainting, Flatulence, Heartburn, Insomnia, Sleepiness


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Expert advice for SELGIN

  • Inform the doctor if you are suffering from hypertension, chest pain, palpitation (thumping, pounding or fluttering sensation in the chest), irregular heartbeat (arrhythmia), liver or kidney problems, stomach ulcers, sleep problems, glucose intolerance, and phenylketonuria (an inherited condition in which a special diet must be followed to prevent mental retardation).
  • Inform the doctor if you are being treated for any mental illness or have history of any unusual urges and/or behaviors (such as excessive gambling or excessive sexual behavior).
  • Seek advice if you are planning to undergo any surgery as selegiline may interfere with general anaesthetics.
  • Do not drink alcohol as it may worsen the side effects.
  • Do not drive or operate any machinery if selegiline affects your alertness.
  • At least 14 days should lapse between the discontinuation of selegiline and initiation of treatment with any drug known to interact with selegiline such as moclobemide, rasagiline, antidepressants, etc.

Frequently asked questions for SELGIN


Q. Is selegiline safe?
Selegiline is safe if used at doses and for duration advised by your doctor. 
Q. Is selegiline a stimulant?
Selegiline can stimulate the brain to cause mood changes, anxiety, agitation, hallucinations, confusion, sleep disturbances etc. 
Q. Is selegiline addictive?
Selegiline is not addictive.
Q. Is selegiline a dopamine agonist?
Selegiline is not a dopamine agonist. It enhances the action of dopamine (either natural dopamine or dopamine obtained from conversion of levodopa) in brain by preventing its breakdown.
Q. Does selegiline need to be tapered?
Selegiline needs to be tapered and should not be suddenly stopped as it may cause fever, sweating, stiff muscles, and loss of consciousness if abruptly discontinued. 
Q. Is selegiline neuroprotective?
Selegiline is neuroprotective as it slows the progression of Parkinson's disease.
Q. Does selegiline cause weight loss/weight gain?
Selegiline causes weight loss.


Content on this page was last updated on 24 June, 2016, by Dr. Varun Gupta (MD Pharmacology)