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Ruftuf 60mg Tablet 1
Ruftuf 60mg Tablet 2
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Ruftuf 60mg Tablet

Raloxifene (60mg)
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Ruftuf 60mg Tablet is a medicine used in the treatment and prevention of osteoporosis in postmenopausal women. It helps in preventing bone loss that can develop in women after menopause. It makes the bone stronger and lowers the risk of fractures.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 31 Aug 2026 | 11:12 AM (IST)
₹81.7 MRP ₹92.8112% off 
 
 
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General Information

The content is shown in English
Ruftuf 60mg Tablet 1
Ruftuf 60mg Tablet 2

Product introduction

Ruftuf 60mg Tablet can be taken with or without food. Take it regularly and do not stop taking the medicine even if you get better until that doctor tells you it is alright to stop. Along with taking the medicine, exercise regularly to strengthen muscles around the affected joint, and manage your weight. You should also avoid smoking and excessive consumption of alcohol while on treatment with this medicine.

The most common side effects of this medicine include hot flashes, leg cramps, peripheral edema, flu-like symptoms, joint pain, and sweating. If any of these side effects do not resolve with time or get worsen, you should let your doctor know. Your doctor may help with ways to reduce or prevent these symptoms by reducing the dose or prescribing an alternative medicine.

To make sure the medicine is safe for you, before taking this medicine, let your doctor know all the other medicines you are taking. Also tell your doctor if you have any problems with your heart, kidneys, or liver. If you are pregnant or breastfeeding, consult your doctor first before taking this medicine.

Benefits of Ruftuf Tablet

Treatment and prevention of Post menopausal osteoporosis
Osteoporosis is a common condition that weakens bones, making them fragile and more likely to break. It often occurs in women after menopause (end of a woman's menstrual cycles) and is known as post-menopausal osteoporosis. Ruftuf 60mg Tablet helps to keep your bones strong and healthy and reduces the risk of osteoporosis. It also helps maintain bone density and reduces your risk of bone fracture. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.

Side effects of Ruftuf Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ruftuf
  • Leg cramps
  • Hot flashes
  • Peripheral edema
  • Flu-like symptoms
  • Joint pain
  • Sweating

How to use Ruftuf Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ruftuf 60mg Tablet may be taken with or without food.

How Ruftuf Tablet works

Ruftuf 60mg Tablet works like estrogen, a natural female hormone to stop the bone loss that can develop in women after menopause.

Quick tips

  • You have been prescribed Ruftuf 60mg Tablet for the treatment of and prevention of postmenopausal osteoporosis.
  • Consult your doctor immediately if you notice lumps in your breast, sudden weakness, chest pain, vision problems, and pain, swelling, warmth, or redness in one or both legs.
  • Inform your doctor if you are on estrogen therapy.
  • Inform your doctor immediately if you observe bleeding/spotting from the vagina during the treatment.
  • Try to increase body movements and do not restrict yourself at one place or position for a long time while taking Ruftuf 60mg Tablet.
  • Remember to do light exercises such as brisk walking to keep yourself active.
  • Try to include calcium and vitamin D-rich food in your diet like dairy products, green leafy vegetables, egg yolk or simply get it naturally from sunlight.
  • Osteoporosis makes your bones weaker, they may break more easily if you fall. You can try to reduce the risk of falls by wearing well-fitting shoes or slippers and checking your home for hazards such as uneven rugs, trailing wires, and slippery floors.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Ruftuf 60mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Ruftuf 60mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Ruftuf 60mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

SAFE
Ruftuf 60mg Tablet does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Ruftuf 60mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Ruftuf 60mg Tablet is not recommended in patients with severe kidney disease.
Liver

Liver

CAUTION
Ruftuf 60mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
All

Interaction with drugs

Taking Ruftuf with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Cholestyramine (Oral Route)

Do not consume Raloxifene with Cholestyramine.
Severe

Estradiol (Oral Route)

Do not consume Raloxifene with Estradiol. If concurrent use is essential, please consult your doctor.
Severe

Progesterone (Injection Route)

Do not consume Raloxifene with Progesterone. If concurrent use is essential, please consult your doctor. Progesterone may reduce the efficacy of Raloxifene.
Severe

Allylestrenol (Oral Route)

Do not consume Raloxifene with Allylestrenol. If concurrent use is essential, please consult your doctor. Allylestrenol may reduce the efficacy of Raloxifene.
Severe

Conjugated Estrogens (Oral Route)

Do not consume Raloxifene with Conjugated Estrogens. If concurrent use is essential, please consult your doctor. Conjugated Estrogens may reduce the efficacy of Raloxifene.

Frequently asked questions

Ruftuf 60mg Tablet is used to prevent and treat osteoporosis in postmenopausal women. Osteoporosis causes bones to become weak and fragile, increasing the risk of fractures, particularly in the spine and hips. By helping maintain bone strength, Ruftuf 60mg Tablet reduces the risk of bone loss and supports long-term bone health.
Ruftuf 60mg Tablet contains Raloxifene, a selective estrogen receptor modulator (SERM). It acts like estrogen on bones, helping slow bone breakdown and maintain bone density after menopause. Unlike natural estrogen, Raloxifene acts differently in various tissues of the body, allowing it to support bone health while producing different effects in other organs.
Yes, Ruftuf 60mg Tablet can generally be taken with or without food. Choose a time that is convenient for you and take it consistently each day as advised by your doctor.
Osteoporosis is a long-term condition, and treatment with Ruftuf 60mg Tablet may continue for an extended period depending on your bone health and fracture risk. Your doctor will periodically review your treatment and determine how long you should continue taking the medicine.
Ruftuf 60mg Tablet is primarily prescribed for postmenopausal women who have osteoporosis or are at increased risk of developing osteoporosis. Your doctor will assess factors such as age, bone density, fracture history, and overall health before recommending treatment.
Changes in bone density occur gradually. While you may not notice any immediate effects, regular use of Ruftuf 60mg Tablet helps protect bone strength over time. Your doctor may monitor your progress with periodic bone density assessments.
Many individuals taking treatment for osteoporosis may also require adequate Calcium and Vitamin D intake to support bone health. Your doctor can advise whether dietary changes or supplements are needed alongside Ruftuf 60mg Tablet.
Weight-bearing activities such as walking and other doctor-recommended exercises help maintain bone strength and mobility. Combining healthy lifestyle habits with treatment may help improve long-term bone health outcomes.
Remaining inactive for prolonged periods may increase certain health risks and can negatively affect overall mobility and bone health. Staying physically active, where appropriate, may help support circulation, muscle strength, and bone function.
Inform your doctor if you are using hormone replacement therapy or any medicine containing estrogen. Your doctor will determine whether these treatments can be used together and recommend the most appropriate approach for your condition.
A balanced diet rich in Calcium, adequate Vitamin D intake, regular exercise, avoiding smoking, and maintaining a healthy body weight may help support bone strength and complement the benefits of Ruftuf 60mg Tablet.
Your doctor may periodically assess your bone health through bone density scans and routine follow-up visits. These evaluations help determine how well the treatment is working and whether any adjustments are needed.

Fact Box

Chemical Class

Aryl- phenyl ketones

Habit Forming

No

Therapeutic Class

GYNAECOLOGICAL

Action Class

Selective estrogen receptor modulators (SERM)- Osteoporosis

Related lab tests

References

  1. Bikle DD. Agents That Affects Bone Mineral Homoestasis. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 766.
  2. Levin ER, Hammes SR. Estrogens and Progestins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1177-80.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1191-92.
  4. Raloxifene. Indianapolis, Indiana: Eli Lilly and Company; 1997 [revised Jul. 2007]. [Accessed 02 Apr. 2019] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Ajanta Pharma Limited
Address: Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India

Vendor Details

Country of origin: India
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