Romiset Injection
Prescription Required
View available alternative with same salt composition
Product introduction
Romiset Injection is used in the treatment of chronic immune thrombocytopenia in patients who have had an insufficient response to other treatments like corticosteroids, immunoglobulins, or splenectomy.
Romiset Injection is given by your doctor or nurse, who will make sure you get the right amount. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen.
The most common side effects are headache, joint pain, insomnia, muscle pain, pain in extremity, abdominal pain, indigestion, and paresthesia (tingling or pricking sensation). Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It can also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can make dizziness worse.
Before getting this medicine, you should let your doctor know if you have or had a blood clot, bleeding problems, or have liver or kidney problems. Let your doctor also know about all other medications you are taking as some may affect or be affected by this medicine.
Uses of Romiset Injection
- Chronic idiopathic thrombocytopenia
- Chronic immune thrombocytopenia
Benefits of Romiset Injection
In Chronic immune thrombocytopenia
Chronic immune thrombocytopenia is a condition of low levels of platelets in our blood. Platelets are those cells that help in clotting and control bleeding. Romiset Injection helps in controlling bleeding by speeding up blood clotting. It helps to prevent excessive loss of blood, stops bleeding and enhances the healing process. It is given by a doctor or nurse and should not be self-administered.
Side effects of Romiset Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Romiset
- Headache
- Joint pain
- Dizziness
- Insomnia (difficulty in sleeping)
- Muscle pain
- Pain in extremities
- Abdominal pain
- Indigestion
- Paresthesia (tingling or pricking sensation)
How to use Romiset Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Romiset Injection works
Romiset Injection is a thrombopoietin receptor agonist. It works in the same way as thrombopoietin (TPO). It helps in increasing platelet production through activation of the thrombopoietin receptor.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Romiset Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
The safety of Romiset Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding
SAFE IF PRESCRIBED
Romiset Injection may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving
CAUTION
Romiset Injection may affect your driving ability if your blood sugar becomes too low or too high. Monitor your blood glucose and avoid driving if affected.
Kidney
CONSULT YOUR DOCTOR
There is limited data available on the use of Romiset Injection in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited data available on the use of Romiset Injection in patients with liver disease.
What if you forget to take Romiset Injection?
If you missed a dose of Romiset Injection, consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Romiset Injection
₹3294/Injection
Romy Injection
Intas Pharmaceuticals Ltd
₹4109.06/injection
21% costlier
Augplat 250mcg Injection
Zydus Cadila
₹3843/injection
13% costlier
Quick tips
- Romiset Injection is used to increase the number of platelets (cells that help the blood to clot) in order to decrease the risk of bleeding in adults.
- Your platelet level will be checked for at least 2 weeks after you finish your treatment with Romiset Injection.
- Inform your doctor if you have or have ever had a blood clot, bleeding problems, any type of cancer that affects your blood cells. Also, tell your doctor if you have had your spleen removed.
- You may experience joint or muscle pain as a result of this medication. Ask your healthcare provider if you may take mild pain medicine to relieve this.
- Avoid sun exposure. Wear SPF 15 (or higher) sunblock and protective clothing.
- Continue to avoid activities that may cause injury and bleeding during your treatment with Romiset Injection.
Fact Box
Chemical Class
Peptides
Habit Forming
No
Therapeutic Class
BLOOD RELATED
Action Class
Thrombopoietin Receptor Agonists (TPO-RAs)
Interaction with drugs
Taking Romiset with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Your doctor may monitor your platelet count frequently along with your overall treatment and adjust the doses as per the observations.
Concurrent use may increase blood platelet c
Your doctor may monitor your platelet count frequently along with your overall treatment and adjust the doses as per the observations.
Concurrent use may increase blood platelet c
Your doctor may monitor your platelet count frequently along with your overall treatment and adjust the doses as per the observations.
Concurrent use may increase blood platelet c
Your doctor may monitor your platelet count frequently along with your overall treatment and adjust the doses as per the observations.
Concurrent use may increase blood platelet c
Your doctor may monitor your platelet count frequently along with your overall treatment and adjust the doses as per the observations.
Concurrent use may increase blood platelet c
Patient concerns
FAQs
What is Romiset Injection used for?
Romiset Injection is used to raise low platelet counts in adults and in children one year and older with immune thrombocytopenia (ITP) who did not respond enough to treatments like steroids, immunoglobulins, or spleen removal. It is also used once to improve survival after high‑dose radiation exposure (acute radiation syndrome).
Is Romiset Injection used to make platelet counts normal?
No, the goal is to keep platelets around 50,000 per microliter to reduce bleeding risk. Romiset Injection should not be used to “normalize” platelet counts because very high platelet levels can increase the risk of blood clots.
Who should not receive Romiset Injection?
There are no listed absolute contraindications of the Romiset Injection, but it must not be used for low platelets due to myelodysplastic syndrome (MDS) or causes other than immune thrombocytopenia (ITP), and clinicians will evaluate risks in people with active serious clots or liver disease due to clot risks.
Can Romiset Injection stop working suddenly?
Yes, in some people, Romiset Injection may stop working due to the development of neutralizing antibodies or other factors. If platelet counts don’t improve after four weeks at the highest dose, treatment is usually stopped and other causes for low platelets are investigated.
What are the serious side effects of Romiset Injection?
Serious side effects of Romiset Injection include signs of blood clots (leg swelling/pain, chest pain, sudden breathlessness, sudden weakness, trouble speaking, severe headache), heavy bleeding or new bruising, severe belly pain (possible portal vein thrombosis), or severe allergic reactions (swelling, hives, breathing trouble). Seek immediate medical attention if you experience any of these symptoms.
How often are blood tests required during and after Romiset Injection treatment?
Weekly platelet counts and complete blood counts are needed while the Romiset Injection dose is being adjusted, then monthly once platelet count stabilizes. After stopping this medicine, weekly platelet counts are needed for at least two weeks because platelets can drop below previous levels (“rebound”).
Does liver disease change the risks with Romiset Injection?
Portal vein thrombosis (a clot in a liver vein) has been reported in people with or without chronic liver disease who are receiving Romiset Injection. Clinicians weigh risks carefully in liver disease and avoid targeting normal platelet counts.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Romiplostim [FDA Label]. Thousand Oaks, CA: Amgen Inc.; 2008. [Accessed 05 Feb. 2020] (online) Available from:
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1233-34.
- Romiplostim [EMC SmPC]. Cambridge, UK: Amgen Ltd.; 2013 [revised Jan. 2018]. [Accessed 05 Feb. 2020] (online) Available from:
- Romiplostim [Presscribing Information]. Thousand Oaks, California: Amgen Inc.; 2021. [Accessed 25 Jul. 2024] (online) Available from:
Marketer details
Name: Alkem Laboratories Ltd
Address: Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Country of origin: India
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₹3294
Inclusive of all taxes
MRP₹3392.8 3% OFF
1.0 Injection in 1 vial
SOLD OUT
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