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Danazol

INFORMATION

Uses

Danazol is used in the treatment of endometriosis and benign fibrocystic breast disease.

Common side effects

Nausea, Palpitations, Pleural pain, Liver disorder, Abnormal blood cell count, Abnormal hair growth on a women face and body, Acne, Aggravation of convulsion, Alterations in thyroid hormone levels, Altered libido, Anxiety, Joint pain, Joint swelling, Blood in urine, Breast size decreased, Carpal tunnel syndrome, Clitoromegaly (frequent congenital malformation), Decreased sperm count, Dizziness, Epigastric pain, Fluid retention, Flushing, Glucose intolerance, Hair loss, Headache, Heart attack, Increased appetite, Increased blood pressure, Increased creatine phosphokinase level in blood, Increased intracranial pressure, Irregular menstrual cycle, Lung inflammation, Migraine, Muscle cramp, Muscle twitching, Rash, Skin disorder, Tachycardia, Tremor, Vaginal irritation, Vaginal dryness, Vertigo, Visual impairment, Voice change, Weight gain

AVAILABLE MEDICINE

Expert advice

  • If you are taking danazol to treat endometriosis or fibrocystic breast disease, you should start the medication during a menstrual period.
  • Consult your doctor if you are suffering from any of the following conditions: liver, kidney or heart disease, illness that can worsen by fluid retention, diabetes, polycythemia (an illness in which blood gets thicker), epilepsy, lipid disorder, migraine, and if you have shown marked or persistent androgenic reaction to previous gonadal steroid therapy.
  • Stop taking danazol if you develop virilization (development of male secondary sex characters).
  • Stop taking danazol and seek advice if you experience signs and symptoms of papilledema, headache, visual disturbances, raised intracranial pressure, jaundice or other liver disturbance, thrombosis or thromboembolism.
  • Taking danazol may increase your risk of ovarian cancer. Seek medical advice for necessary precautions.
  • Carry out liver function tests and blood counts at regular intervals of time.
  • Do not drink alcohol while on danazol therapy as it can make you feel sick or short of breath.
  • If you are receiving danazol for more than 6 months, it is important to carry out liver ultrasonography twice in a year.
  • Do not take danazol if you have rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption.

Frequently asked questions

Danazol

Q.Is danazol safe?
Danazol is safe if used at prescribed dose and duration as advised by your doctor

Q.Is danazol a progesterone/steroid/anabolic steroid/contraceptive (birth control)/narcotic?
Danazol is a synthetic steroid having additional progestogenic activity. It is not contraceptive (birth control)/narcotic

Q.Is danazol a controlled substance?
Danazol is not a controlled substance.


Content on this page was last updated on 05 December, 2016, by Dr. Varun Gupta (MD Pharmacology)