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Rexnip Tablet

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 17 Jan 2026 | 04:41 PM (IST)
Rexnip Tablet is a pain-relieving medicine. It is taken to treat inflammatory conditions, including joint disorders such as rheumatoid arthritis, postoperative painful conditions, fever, and period pain.
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General Information

The content is shown in English
Rexnip Tablet image
Rexnip Tablet image

Product introduction

Rexnip Tablet should be taken with food. This will prevent you from getting an upset stomach. In general, you should try to use the smallest amount necessary to control your symptoms, for the shortest possible time. You should take this medicine regularly while you need it. Try not to miss doses, as this will make the medicine less effective.


Some common side effects of this medicine include diarrhea, nausea, and vomiting. If any of these side effects do not resolve with time or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.


To make sure Rexnip Tablet is safe for you, let your doctor know if you have any medical conditions or disorders. You should also tell your doctor all the other medicines you are using or taking. Rexnip Tablet is not recommended for use in pregnant or lactating women and patients with kidney or liver diseases.


Note: As per the Ministry of Health and Family Welfare, Rexnip Tablet is banned for children under 12 years of age.

Uses of Rexnip Tablet

Benefits of Rexnip Tablet

Treatment of Fever
Rexnip Tablet is also used to reduce a high temperature (fever). It works by blocking the release of certain chemical messengers that cause fever. It may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor.
Pain relief
Rexnip Tablet is used to treat aches and pains. It blocks chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis, and muscle aches. This medicine is very widely used and very rarely causes side effects if taken at the right dosage.

Take it as it is prescribed to get the most benefit. Do not take more or longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time.

Side effects of Rexnip Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Rexnip
  • Increased liver enzymes
  • Vomiting
  • Nausea
  • Diarrhea

How to use Rexnip Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rexnip Tablet should be taken with or after food.

How Rexnip Tablet works

Rexnip Tablet is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).

Quick tips

  • Take it with food or milk to prevent an upset stomach.
  • Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
  • Inform your doctor if you have a history of heart disease or stroke.
  • Avoid consuming alcohol while taking Rexnip Tablet as it can increase your risk of stomach problems.
  • Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Rexnip Tablet. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Rexnip Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

UNSAFE
Rexnip Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Rexnip Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

SAFE IF PRESCRIBED
Rexnip Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.
Use of Rexnip Tablet is not recommended in patients with severe kidney disease.
Liver

Liver

UNSAFE
Rexnip Tablet is unsafe to use in patients with liver disease and should be avoided.

Interaction with drugs

Taking Rexnip with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Tacrolimus (Oral Route)

If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Frequently asked questions

Rexnip Tablet is not an antibiotic, it belongs to the class of medicines known as non-steroidal anti-inflammatory drugs (NSAIDs; pain-relieving drugs) which help in relieving pain associated with various conditions.
Rexnip Tablet and paracetamol belong to the same class of medicines known as non-steroidal anti-inflammatory drugs (NSAIDs; pain-relieving drugs). Taking the two medicines together is not advisable as it may increase the potential for gastric ulceration and bleeding. However, please consult your doctor before using the two medicines together.
Rexnip Tablet is safe to use if taken at the prescribed dose and duration advised by your doctor.
Rexnip Tablet can be taken for a headache only when advised by your doctor.
No, Rexnip Tablet is not banned in India. However, as per the Ministry of Health and Family Welfare, Rexnip Tablet is banned for children under 12 years of age.
No, Rexnip Tablet is not safe to be used in pregnancy, especially in the last three months. There have been reports of kidney failure in newborn babies if the mother was taking Rexnip Tablet in the late stage of pregnancy. Consult your doctor before taking any medicine during pregnancy.

Fact Box

Chemical Class

Diphenylethers

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

NSAID's-Non-Selective COX 1&2 Inhibitors (Others)

Related lab tests

References

  1. Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 509p. 992.
  2. Nimesulide [Summary of Product Characteristics]. [Accessed 05 May 2025] (online) Available from:
  3. Nimesulide. Jerusalem: Rafa Laboratories Ltd.; 2012 [Accessed 17 Jan 2026] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sebert Lifesciences
Address: Plot No-414 , 1St Floor, Phase-1, Industrial Area, Panchkula, Haryana

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Rexnip Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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