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Nimesulide is used to treat acute pain, osteoarthritis (pain and swelling of joints due to degeneration) and pain during periods.

How it works

Nimesulide belongs to a class of medications called non-steroidal anti-inflammatory drugs (NSAIDs) which works by blocking the production of prostaglandins (a chemical associated with pain) thereby relieving pain and inflammation.

Common side effects

Nausea, Rash, Abnormal blood cell count, Anemia, Constipation, Diarrhoea, Dizziness, Shortness of breath, Gastritis, Hypersensitivity reaction, Increased blood pressure, Swelling, Increased sweating, Itching, Liver enzyme increased, Vomiting


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Expert advice

Do not take this medicine:
  • if you are allergic to Nimesulide, or any of the other ingredients of this medicine.
  • if you have or had gastric ulceration/bleeding in the past.
Do not consume more than one pain-relieving medication at a time.Caution is advised with the use of Nimesulide if you have bleeding disorder. Nimesulide may cause infertility in women, and should not be consumed by women planning to become pregnant This medicine should not be given to a child under 12 years of age.
Treatment with Nimesulide should be of short duration and discontinued if it is of no help.

Frequently asked questions


Q. Is Nimesulide an antibiotic?
No, Nimesulide is non-steroidal anti-inflammatory drug (NSAIDs; pain-relieving drug) which relieves acute pain in conditions like joint pain and period pain. However, it may be used with antibiotics to relieve pain associated with certain infections.
Q. Can I take Nimesulide with paracetamol or ibuprofen?
Nimesulide, paracetamol and ibuprofen are non-steroidal anti-inflammatory drugs (NSAIDs; pain-relieving drugs). Taking two NSAID drugs together is not advisable as it may increase the potential for gastric ulceration and bleeding.
Q. Does Nimesulide contain aspirin or sulphur?
No. Nimesulide is a non-steroidal anti-inflammatory drug (NSAIDs; pain-relieving drug) doesn’t contain aspirin or sulphur.
Q. Is Nimesulide safe?
Nimesulide is safe at prescribed dose and duration as advised by your doctor.

Content on this page was last updated on 18 October, 2016, by Dr. Varun Gupta (MD Pharmacology)